Bjarne Winther Kristensen
Clinical Professor
Department of Clinical Medicine
Blegdamsvej 3
2200 København N.
Kristensen Group
Ole Maaløes Vej 5
2200 København N.
Member of:
Pathology
Invasion of primary glioma- and cell line-derived spheroids implanted into corticostriatal slice cultures
Aaberg-Jessen, C., Nørregaard, A., Christensen, K., Pedersen, C. B., Andersen, C. & Kristensen, Bjarne Winther, 2013, In: International Journal of Clinical and Experimental Pathology. 6, 4, p. 546-60 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
Overexpression of TIMP-1 and Sensitivity to Topoisomerase Inhibitors in Glioblastoma Cell Lines
Aaberg-Jessen, C., Fogh, L., Sørensen, M. D., Halle, B., Brünner, N. & Kristensen, Bjarne Winther, Jan 2019, In: Pathology oncology research : POR. 25, 1, p. 59-69 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Global immune fingerprinting in glioblastoma patient peripheral blood reveals immune-suppression signatures associated with prognosis
Alban, T. J., Alvarado, A. G., Sorensen, M. D., Bayik, D., Volovetz, J., Serbinowski, E., Mulkearns-Hubert, E. E., Sinyuk, M., Hale, J. S., Onzi, G. R., McGraw, M., Huang, P., Grabowski, M. M., Wathen, C. A., Ahluwalia, M. S., Radivoyevitch, T., Kornblum, H. I., Kristensen, Bjarne Winther, Vogelbaum, M. A. & Lathia, J. D., 2 Nov 2018, In: JCI Insight. 3, 21Research output: Contribution to journal › Journal article › Research › peer-review
Intrakraniale meningeomer
Andersen, M. S., Pedersen, C. B., Mathiesen, T., Poulsgaard, L., Kristensen, Bjarne Winther, Halle, B. & Poulsen, F. R., 21 Jan 2019, In: Ugeskrift for Laeger. 181, 4, p. V07180489Research output: Contribution to journal › Journal article › Research › peer-review
Cardiac leiomyosarcoma, a case report
Andersen, R. E., Kristensen, Bjarne Winther & Gill, S., 2013, In: International Journal of Clinical and Experimental Pathology. 6, 6, p. 1197-9 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tumor-associated microglia and macrophages in the glioblastoma microenvironment and their implications for therapy
Andersen, R. S., Anand, A., Harwood, D. S. L. & Kristensen, Bjarne Winther, 2021, In: Cancers. 13, 17, 26 p., 4255.Research output: Contribution to journal › Review › Research › peer-review
Non-Hodgkin-lymfom i larynx
Andriychuk, A. & Kristensen, Bjarne Winther, 18 Oct 2010, In: Ugeskrift for Laeger. 172, 42, p. 2901-2 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
Myeloid-Derived Suppressor Cell Subsets Drive Glioblastoma Growth in a Sex-Specific Manner
Bayik, D., Zhou, Y., Park, C., Hong, C., Vail, D., Silver, D. J., Lauko, A., Roversi, G., Watson, D. C., Lo, A., Alban, T. J., McGraw, M., Sorensen, M., Grabowski, M. M., Otvos, B., Vogelbaum, M. A., Horbinski, C., Kristensen, B. W., Khalil, A. M., Hwang, T. H. & 3 others, , Aug 2020, In: Cancer Discovery. 10, 8, p. 1210-1225 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
TLR4 in glioblastoma-when cancer stem cells ignore "danger signals"
Beier, C. P. & Kristensen, Bjarne Winther, 2017, In: Stem Cell Investigation. 4, p. 66Research output: Contribution to journal › Journal article › Research › peer-review
Aberrant neuronal differentiation is common in glioma but is associated neither with epileptic seizures nor with better survival
Beier, C. P., Rasmussen, T., Dahlrot, R. H., Tenstad, H. B., Aarø, J. S., Sørensen, M. F., Heimisdóttir, S. B., Sørensen, M. D., Svenningsen, P., Riemenschneider, M. J., Beier, D. & Kristensen, Bjarne Winther, 8 Oct 2018, In: Scientific Reports. 8, 1, p. 14965Research output: Contribution to journal › Journal article › Research › peer-review
The metabotropic glutamate receptor agonist 1S,3R-ACPD stimulates and modulates NMDA receptor mediated excitotoxicity in organotypic hippocampal slice cultures
Blaabjerg, M., Kristensen, Bjarne Winther, Bonde, C. & Zimmer, J., 13 Apr 2001, In: Brain Research. 898, 1, p. 91-104 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
Widespread inflammation in CLIPPERS syndrome indicated by autopsy and ultra-high-field 7T MRI
Blaabjerg, M., Ruprecht, K., Sinnecker, T., Kondziella, D., Niendorf, T., Kerrn-Jespersen, B. M., Lindelof, M., Lassmann, H., Kristensen, Bjarne Winther, Paul, F. & Illes, Z., Jun 2016, In: Neurology: Neuroimmunology & Neuroinflammation. 3, 3, p. e226Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glioneuronal tumor with ATRX alteration, kinase fusion and anaplastic features (GTAKA): a molecularly distinct brain tumor type with recurrent NTRK gene fusions
Bogumil, H., Sill, M., Schrimpf, D., Ismer, B., Blume, C., Rahmanzade, R., Hinz, F., Cherkezov, A., Banan, R., Friedel, D., Reuss, D. E., Selt, F., Ecker, J., Milde, T., Pajtler, K. W., Schittenhelm, J., Hench, J., Frank, S., Boldt, H. B., Kristensen, B. W. & 32 others, , 2023, In: Acta Neuropathologica. 145, p. 667–680Research output: Contribution to journal › Journal article › Research › peer-review
GDNF and neublastin protect against NMDA-induced excitotoxicity in hippocampal slice cultures
Bonde, C., Kristensen, Bjarne Winther, Blaabjerg, M., Johansen, T. E., Zimmer, J. & Meyer, M., 18 Dec 2000, In: NeuroReport. 11, 18, p. 4069-73 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
Sodium fluorescein shows high surgeon-reported usability in glioblastoma surgery
Bömers, J. P., Danielsen, M. E., Schulz, M. K., Halle, B., Kristensen, Bjarne Winther, Sørensen, M. D., Poulsen, F. R. & Pedersen, C. B., Dec 2020, In: Journal of the Irish Colleges of Physicians and Surgeons. 18, 6, p. 344-348 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
D-2-hydroxyglutarate regulates human brain vascular endothelial cell proliferation and barrier function
Cao, C., Zhang, L., Sorensen, M. D., Reifenberger, Guido, Kristensen, Bjarne Winther, McIntyre, T. M. & Lin, F., 2023, In: Journal of Neuropathology and Experimental Neurology. 82, 11, p. 921-933 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
CD133 identifies perivascular niches in grade II-IV astrocytomas
Christensen, K., Schrøder, H. D. & Kristensen, Bjarne Winther, Nov 2008, In: Journal of Neuro-Oncology. 90, 2, p. 157-70 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
CD133+ niches and single cells in glioblastoma have different phenotypes
Christensen, K., Schrøder, H. D. & Kristensen, Bjarne Winther, Aug 2011, In: Journal of Neuro-Oncology. 104, 1, p. 129-43 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
Immunohistochemical expression of stem cell, endothelial cell, and chemosensitivity markers in primary glioma spheroids cultured in serum-containing and serum-free medium
Christensen, K., Aaberg-Jessen, C., Andersen, C., Goplen, D., Bjerkvig, R. & Kristensen, Bjarne Winther, May 2010, In: Neurosurgery. 66, 5, p. 933-47 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
Tumorstamceller i gliomer--et mål for fremtidig behandling?
Christensen, K., Schrøder, H. D. & Kristensen, Bjarne Winther, 15 Sep 2008, In: Ugeskrift for Laeger. 170, 38, p. 2968-70 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
Dual time-point FDG PET/CT and FDG uptake and related enzymes in lymphadenopathies: preliminary results
Christlieb, S. B., Strandholdt, C. N., Olsen, B. B., Mylam, K. J., Larsen, T. S., Nielsen, A. L., Rohde, M., Gerke, O., Olsen, K. E., Møller, M. B., Kristensen, Bjarne Winther, Abildgaard, N., Alavi, A. & Høilund-Carlsen, P. F., Sep 2016, In: European Journal of Nuclear Medicine and Molecular Imaging. 43, 10, p. 1824-36 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
Characterization of the TNF and IL-1 systems in human brain and blood after ischemic stroke
Clausen, B. H., Wirenfeldt, M., Høgedal, S. S., Frich, L. H., Nielsen, H. H., Schrøder, H. D., Østergaard, K., Finsen, B., Kristensen, Bjarne Winther & Lambertsen, K. L., 5 Jun 2020, In: Acta neuropathologica communications. 8, 1, p. 81Research output: Contribution to journal › Journal article › Research › peer-review
Cell therapy centered on IL-1Ra is neuroprotective in experimental stroke
Clausen, B. H., Lambertsen, K. L., Dagnæs-Hansen, F., Babcock, A. A., von Linstow, C. U., Meldgaard, M., Kristensen, Bjarne Winther, Deierborg, T. & Finsen, B., May 2016, In: Acta Neuropathologica. 131, 5, p. 775-91 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
Conditional ablation of myeloid TNF increases lesion volume after experimental stroke in mice, possibly via altered ERK1/2 signaling
Clausen, B. H., Degn, M., Sivasaravanaparan, M., Fogtmann, T., Andersen, M. G., Trojanowsky, M. D., Gao, H., Hvidsten, S., Baun, C., Deierborg, T., Finsen, B., Kristensen, Bjarne Winther, Bak, S. T., Meyer, M., Lee, J., Nedospasov, S. A., Brambilla, R. & Lambertsen, K. L., 7 Jul 2016, In: Scientific Reports. 6, p. 29291Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The presence of TIM-3 positive cells in WHO grade III and IV astrocytic gliomas correlates with isocitrate dehydrogenase mutation status
D. Sørensen, M., Nielsen, O., Reifenberger, G. & Kristensen, Bjarne Winther, 2021, In: Brain Pathology. 31, 3, 20 p., e12921.Research output: Contribution to journal › Journal article › Research › peer-review
Posttreatment Effect of MGMT Methylation Level on Glioblastoma Survival
Dahlrot, R. H., Larsen, P., Boldt, H. B., Kreutzfeldt, M. S., Hansen, S., Hjelmborg, J. B. & Kristensen, Bjarne Winther, 1 Jul 2019, In: Journal of Neuropathology and Experimental Neurology. 78, 7, p. 633-640 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
A population-based study of low-grade gliomas and mutated isocitrate dehydrogenase 1 (IDH1)
Dahlrot, R. H., Kristensen, Bjarne Winther, Hjelmborg, J., Herrstedt, J. & Hansen, S., Sep 2013, In: Journal of Neuro-Oncology. 114, 3, p. 309-17 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
A population-based study of high-grade gliomas and mutated isocitrate dehydrogenase 1
Dahlrot, R. H., Kristensen, Bjarne Winther, Hjelmborg, J., Herrstedt, J. & Hansen, S., 2013, In: International Journal of Clinical and Experimental Pathology. 6, 1, p. 31-40 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Novel approaches for quantifying protein biomarkers in gliomas: benefits and pitfalls
Dahlrot, R. H., Sørensen, M. D., Rosager, A. M., Hellwege, S., Bangsø, J. A., Rosenberg, T., Petterson, S. A., Klitkou, J., Fosmark, S., Hansen, S. & Kristensen, Bjarne Winther, Jul 2014, In: CNS oncology. 3, 4, p. 287-98 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Clinical value of CD133 and nestin in patients with glioma: a population-based study
Dahlrot, R. H., Hansen, S., Jensen, S. S., Schrøder, H. D., Hjelmborg, J. & Kristensen, Bjarne Winther, 2014, In: International Journal of Clinical and Experimental Pathology. 7, 7, p. 3739-51 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
Prognostic value of Musashi-1 in gliomas
Dahlrot, R. H., Hansen, S., Herrstedt, J., Schrøder, H. D., Hjelmborg, J. & Kristensen, Bjarne Winther, Dec 2013, In: Journal of Neuro-Oncology. 115, 3, p. 453-61 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prognostic role of Ki-67 in glioblastomas excluding contribution from non-neoplastic cells
Dahlrot, R. H., Bangsø, J. A., Petersen, J. K., Rosager, A. M., Sørensen, M. D., Reifenberger, G., Hansen, S. & Kristensen, Bjarne Winther, 2021, In: Scientific Reports. 11, 17918.Research output: Contribution to journal › Journal article › Research › peer-review
What is the clinical value of cancer stem cell markers in gliomas?
Dahlrot, R. H., Hermansen, S. K., Hansen, S. & Kristensen, Bjarne Winther, 2013, In: International Journal of Clinical and Experimental Pathology. 6, 3, p. 334-48 15 p.Research output: Contribution to journal › Review › Research › peer-review
Intermittent, low dose carbon monoxide exposure enhances survival and dopaminergic differentiation of human neural stem cells
Dreyer-Andersen, N., Almeida, A. S., Jensen, P., Kamand, M., Okarmus, J., Rosenberg, T., Friis, S. D., Martínez Serrano, A., Blaabjerg, M., Kristensen, Bjarne Winther, Skrydstrup, T., Gramsbergen, J. B., Vieira, H. L. A. & Meyer, M., 2018, In: PLoS One. 13, 1, p. e0191207Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expression of GDNF and its receptors in glioblastoma
Ewald, J. D., Knudsen, A. M. & Kristensen, Bjarne Winther, 2022, In: Neuro-Oncology. 24, 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
Alternative lengthening of telomeres is the major telomere maintenance mechanism in astrocytoma with isocitrate dehydrogenase 1 mutation
Ferreira, M. S. V., Sørensen, M. D., Pusch, S., Beier, D., Bouillon, A., Kristensen, Bjarne Winther, Brümmendorf, T. H., Beier, C. P. & Beier, F., Mar 2020, In: Journal of Neuro-Oncology. 147, 1, p. 1-14 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
APNG as a prognostic marker in patients with glioblastoma
Fosmark, S., Hellwege, S., Dahlrot, R. H., Jensen, K. L., Derand, H., Lohse, J., Sørensen, M. D., Hansen, S. & Kristensen, Bjarne Winther, 2017, In: PLoS One. 12, 6, p. e0178693Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Redefining germline predisposition in children with molecularly characterized ependymoma: a population-based 20-year cohort
Foss-Skiftesvik, J., Stoltze, U. K., Hansen, Thomas van Overeem, Ahlborn, L. B., Sørensen, E., Ostrowski, Sisse Rye, Kullegaard, S. M. A., Laspiur, A. O., Melchior, L. C., Scheie, David, Kristensen, Bjarne Winther, Skjøth, Jane, Schmiegelow, Kjeld, Wadt, Karin Anna Wallentin & Mathiasen, René, 2022, In: Acta Neuropathologica Communications. 10, 123.Research output: Contribution to journal › Journal article › Research › peer-review
Shift of microRNA profile upon orthotopic xenografting of glioblastoma spheroid cultures
Halle, B., Thomassen, M., Venkatesan, R., Kaimal, V., Marcusson, E. G., Munthe, S., Sørensen, M. D., Aaberg-Jessen, C., Jensen, S. S., Meyer, M., Kruse, T. A., Christiansen, H., Schmidt, S., Mollenhauer, J., Schulz, M. K., Andersen, C. & Kristensen, Bjarne Winther, Jul 2016, In: Journal of Neuro-Oncology. 128, 3, p. 395-404 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Ny behandling af gliomer rettet mod specifikt mikro-RNA
Halle, B., Andersen, C., Schulz, M. K. & Kristensen, Bjarne Winther, 5 Mar 2012, In: Ugeskrift for Laeger. 174, 10, p. 630-3 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
Convection-enhanced delivery of an anti-miR is well-tolerated, preserves anti-miR stability and causes efficient target de-repression: a proof of concept
Halle, B., Marcusson, E. G., Aaberg-Jessen, C., Jensen, S. S., Meyer, M., Schulz, M. K., Andersen, C. & Kristensen, Bjarne Winther, Jan 2016, In: Journal of Neuro-Oncology. 126, 1, p. 47-55 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Estimation of Tumor Volumes by 11C-MeAIB and 18F-FDG PET in an Orthotopic Glioblastoma Rat Model
Halle, B., Thisgaard, H., Hvidsten, S., Dam, J. H., Aaberg-Jessen, C., Thykjær, A. S., Høilund-Carlsen, P. F., Schulz, M. K., Andersen, C. & Kristensen, Bjarne Winther, Oct 2015, In: Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 56, 10, p. 1562-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Comparison of 5-aminolevulinic acid and sodium fluorescein for intraoperative tumor visualization in patients with high-grade gliomas: a single-center retrospective study
Hansen, R. W., Pedersen, C. B., Halle, B., Korshoej, A. R., Schulz, M. K., Kristensen, Bjarne Winther & Poulsen, F. R., 4 Oct 2019, (E-pub ahead of print) In: Journal of Neurosurgery. p. 1-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Drug Repurposing Screen Reveals Glioblastoma Cell Line Susceptibility to Statins
Harwood, Dylan Scott Lykke, Michaelsen, Signe Regner, Mundt, F. & Kristensen, Bjarne Winther, 2021, In: Neuro-Oncology. 23, S6, p. 77-78 2 p.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Proposal of a new grading system for meningioma resection: the Copenhagen Protocol
Haslund-Vinding, Jeppe Lohfert, Skjøth, Jane, Poulsgaard, L., Fugleholm, Kåre, Larsen, Christian Mirian, Maier, A. D., Santarius, T., Poulsen, F. R., Meling, T., Bartek, J. J., Förander, P., Larsen, V. A., Kristensen, Bjarne Winther, Scheie, David, Law, Ian, Ziebell, M. & Mathiesen, Tiit Illimar, 2022, In: Acta Neurochirurgica. 164, p. 229-238Research output: Contribution to journal › Journal article › Research › peer-review
A 4-miRNA signature to predict survival in glioblastomas
Hermansen, S. K., Sørensen, M. D., Hansen, A., Knudsen, S., Alvarado, A. G., Lathia, J. D. & Kristensen, Bjarne Winther, 2017, In: PLoS One. 12, 11, p. e0188090Research output: Contribution to journal › Journal article › Research › peer-review
Inconsistent immunohistochemical expression patterns of four different CD133 antibody clones in glioblastoma
Hermansen, S. K., Christensen, K. G., Jensen, S. S. & Kristensen, Bjarne Winther, Apr 2011, In: Journal of Histochemistry and Cytochemistry. 59, 4, p. 391-407 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
MicroRNA biomarkers in glioblastoma
Hermansen, S. K. & Kristensen, Bjarne Winther, Aug 2013, In: Journal of Neuro-Oncology. 114, 1, p. 13-23 11 p.Research output: Contribution to journal › Review › Research › peer-review
MiR-21 expression in the tumor cell compartment holds unfavorable prognostic value in gliomas
Hermansen, S. K., Dahlrot, R. H., Nielsen, B. S., Hansen, S. & Kristensen, Bjarne Winther, Jan 2013, In: Journal of Neuro-Oncology. 111, 1, p. 71-81 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
miR-21 Is Linked to Glioma Angiogenesis: A Co-Localization Study
Hermansen, S. K., Nielsen, B. S., Aaberg-Jessen, C. & Kristensen, Bjarne Winther, Feb 2016, In: Journal of Histochemistry and Cytochemistry. 64, 2, p. 138-48 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 245405291
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Microglia-Secreted Factors Enhance Dopaminergic Differentiation of Tissue- and iPSC-Derived Human Neural Stem Cells
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Tumor-associated microglia and macrophages in the glioblastoma microenvironment and their implications for therapy
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Expression, prognostic significance and therapeutic implications of PD-L1 in gliomas
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