Bjarne Winther Kristensen
Clinical Professor
Department of Clinical Medicine
Blegdamsvej 3
2200 København N.
Kristensen Group
Ole Maaløes Vej 5
2200 København N.
Member of:
Pathology
- 2019
Frameless stereotactic neuronavigated biopsy: A retrospective study of morbidity, diagnostic yield, and the potential of fluorescence: A single-center clinical investigation
Æbelø, A. M., Noer, V. R., Schulz, M. K., Kristensen, Bjarne Winther, Pedersen, C. B. & Poulsen, F. R., Jun 2019, In: Clinical Neurology and Neurosurgery. 181, p. 28-32 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
Hypofyseadenom
Møller, M. W., Andersen, M. S., Glintborg, D., Pedersen, C. B., Halle, B., Kristensen, Bjarne Winther & Poulsen, F. R., 13 May 2019, In: Ugeskrift for Laeger. 181, 20, V05180331.Research output: Contribution to journal › Review › Research › peer-review
Nonhypoxic pharmacological stabilization of Hypoxia Inducible Factor 1α: Effects on dopaminergic differentiation of human neural stem cells
Hey, S. M., Jensen, P., Ryding, M., Martínez Serrano, A., Kristensen, Bjarne Winther & Meyer, M., Feb 2019, In: European Journal of Neuroscience. 49, 4, p. 497-509 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
Intrakraniale meningeomer
Andersen, M. S., Pedersen, C. B., Mathiesen, T., Poulsgaard, L., Kristensen, Bjarne Winther, Halle, B. & Poulsen, F. R., 21 Jan 2019, In: Ugeskrift for Laeger. 181, 4, p. V07180489Research output: Contribution to journal › Journal article › Research › peer-review
Overexpression of TIMP-1 and Sensitivity to Topoisomerase Inhibitors in Glioblastoma Cell Lines
Aaberg-Jessen, C., Fogh, L., Sørensen, M. D., Halle, B., Brünner, N. & Kristensen, Bjarne Winther, Jan 2019, In: Pathology oncology research : POR. 25, 1, p. 59-69 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
Chordoid meningiomas can be sub-stratified into prognostically distinct DNA methylation classes and are enriched for heterozygous deletions of chromosomal arm 2p
Sievers, P., Stichel, D., Hielscher, T., Schrimpf, D., Reinhardt, A., Wefers, A. K., Reuss, D., Jones, D. T. W., Bewerunge-Hudler, M., Hartmann, C., Baumgarten, P., Wirsching, H-G., Winther-Kristensen, B., Brokinkel, B., Ketter, R., Idoate Gastearena, M. A., Lamszus, K., Seiz-Rosenhagen, M., Mawrin, C., Harter, P. N. & 11 others, , Dec 2018, In: Acta Neuropathologica. 136, 6, p. 975-978 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
Global immune fingerprinting in glioblastoma patient peripheral blood reveals immune-suppression signatures associated with prognosis
Alban, T. J., Alvarado, A. G., Sorensen, M. D., Bayik, D., Volovetz, J., Serbinowski, E., Mulkearns-Hubert, E. E., Sinyuk, M., Hale, J. S., Onzi, G. R., McGraw, M., Huang, P., Grabowski, M. M., Wathen, C. A., Ahluwalia, M. S., Radivoyevitch, T., Kornblum, H. I., Kristensen, Bjarne Winther, Vogelbaum, M. A. & Lathia, J. D., 2 Nov 2018, In: JCI Insight. 3, 21Research output: Contribution to journal › Journal article › Research › peer-review
D-2-Hydroxyglutarate Is an Intercellular Mediator in IDH-Mutant Gliomas Inhibiting Complement and T Cells
Zhang, L., Sorensen, M. D., Kristensen, Bjarne Winther, Reifenberger, G., McIntyre, T. M. & Lin, F., 1 Nov 2018, In: Clinical Cancer Research. 24, 21, p. 5381-5391 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Aberrant neuronal differentiation is common in glioma but is associated neither with epileptic seizures nor with better survival
Beier, C. P., Rasmussen, T., Dahlrot, R. H., Tenstad, H. B., Aarø, J. S., Sørensen, M. F., Heimisdóttir, S. B., Sørensen, M. D., Svenningsen, P., Riemenschneider, M. J., Beier, D. & Kristensen, Bjarne Winther, 8 Oct 2018, In: Scientific Reports. 8, 1, p. 14965Research output: Contribution to journal › Journal article › Research › peer-review
Intraoperative low field MRI in transsphenoidal pituitary surgery
Møller, M. W., Andersen, M. S., Pedersen, C. B., Kristensen, Bjarne Winther & Poulsen, F. R., Jul 2018, In: Endocrine Connections. 7, 7, p. 897-906 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Evaluation of the proliferation marker Ki-67 in gliomas: Interobserver variability and digital quantification
Nielsen, L. A. G., Bangsø, J. A., Lindahl, K. H., Dahlrot, R. H., Hjelmborg, J. V. B., Hansen, S. & Kristensen, Bjarne Winther, 9 Jun 2018, In: Diagnostic Pathology. 13, 1, p. 38Research output: Contribution to journal › Journal article › Research › peer-review
High expression of cystine-glutamate antiporter xCT (SLC7A11) is an independent biomarker for epileptic seizures at diagnosis in glioma
Sørensen, M. F., Heimisdóttir, S. B., Sørensen, M. D., Mellegaard, C. S., Wohlleben, H., Kristensen, Bjarne Winther & Beier, C. P., May 2018, In: Journal of Neuro-Oncology. 138, 1, p. 49-53 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
Heterogenic expression of stem cell markers in patient-derived glioblastoma spheroid cultures exposed to long-term hypoxia
Rosenberg, T., Aaberg-Jessen, C., Petterson, S. A. & Kristensen, Bjarne Winther, Apr 2018, In: CNS oncology. 7, 2, p. CNS15Research output: Contribution to journal › Journal article › Research › peer-review
Hereditary spastic paraplegia type 8: Neuropathological findings
Pehrson, C., Hertz, J. M., Wirenfeldt, M., Stenager, E., Wermuth, L. & Kristensen, Bjarne Winther, Mar 2018, In: Brain Pathology. 28, 2, p. 292-294 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
SuperQuant-assisted comparative proteome analysis of glioblastoma subpopulations allows for identification of potential novel therapeutic targets and cell markers
Verano-Braga, T., Gorshkov, V., Munthe, S., Sørensen, M. D., Kristensen, Bjarne Winther & Kjeldsen, F., 6 Feb 2018, In: Oncotarget. 9, 10, p. 9400-9414 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
Tumour-associated microglia/macrophages predict poor prognosis in high-grade gliomas and correlate with an aggressive tumour subtype
Sørensen, M. D., Dahlrot, R. H., Boldt, H. B., Hansen, S. & Kristensen, Bjarne Winther, Feb 2018, In: Neuropathology and Applied Neurobiology. 44, 2, p. 185-206 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
Intermittent, low dose carbon monoxide exposure enhances survival and dopaminergic differentiation of human neural stem cells
Dreyer-Andersen, N., Almeida, A. S., Jensen, P., Kamand, M., Okarmus, J., Rosenberg, T., Friis, S. D., Martínez Serrano, A., Blaabjerg, M., Kristensen, Bjarne Winther, Skrydstrup, T., Gramsbergen, J. B., Vieira, H. L. A. & Meyer, M., 2018, In: PLoS One. 13, 1, p. e0191207Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
Expression and prognostic value of JAM-A in gliomas
Rosager, A. M., Sørensen, M. D., Dahlrot, R. H., Boldt, H. B., Hansen, S., Lathia, J. D. & Kristensen, Bjarne Winther, Oct 2017, In: Journal of Neuro-Oncology. 135, 1, p. 107-117 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Effects of the lysosomal destabilizing drug siramesine on glioblastoma in vitro and in vivo
Jensen, S. S., Petterson, S. A., Halle, B., Aaberg-Jessen, C. & Kristensen, Bjarne Winther, 7 Mar 2017, In: BMC Cancer. 17, 1, p. 178Research output: Contribution to journal › Journal article › Research › peer-review
Shift of microRNA profile upon glioma cell migration using patient-derived spheroids and serum-free conditions
Munthe, S., Halle, B., Boldt, H. B., Christiansen, H., Schmidt, S., Kaimal, V., Xu, J., Zabludoff, S., Mollenhauer, J., Poulsen, F. R. & Kristensen, Bjarne Winther, Mar 2017, In: Journal of Neuro-Oncology. 132, 1, p. 45-54 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
A 4-miRNA signature to predict survival in glioblastomas
Hermansen, S. K., Sørensen, M. D., Hansen, A., Knudsen, S., Alvarado, A. G., Lathia, J. D. & Kristensen, Bjarne Winther, 2017, In: PLoS One. 12, 11, p. e0188090Research output: Contribution to journal › Journal article › Research › peer-review
APNG as a prognostic marker in patients with glioblastoma
Fosmark, S., Hellwege, S., Dahlrot, R. H., Jensen, K. L., Derand, H., Lohse, J., Sørensen, M. D., Hansen, S. & Kristensen, Bjarne Winther, 2017, In: PLoS One. 12, 6, p. e0178693Research output: Contribution to journal › Journal article › Research › peer-review
Expression and prognostic impact of matrix metalloproteinase-2 (MMP-2) in astrocytomas
Ramachandran, R. K., Sørensen, M. D., Aaberg-Jessen, C., Hermansen, S. K. & Kristensen, Bjarne Winther, 2017, In: PLoS One. 12, 2, p. e0172234Research output: Contribution to journal › Journal article › Research › peer-review
Patterns of diagnostic marker assessment in adult diffuse glioma: a survey of the European Confederation of Neuropathological Societies (Euro-CNS)
Woehrer, A., Kristensen, Bjarne Winther, Vital, A. & Hainfellner, J. A., 2017, In: Clinical Neuropathology. 36 (2017), 1, p. 5-14 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
TLR4 in glioblastoma-when cancer stem cells ignore "danger signals"
Beier, C. P. & Kristensen, Bjarne Winther, 2017, In: Stem Cell Investigation. 4, p. 66Research output: Contribution to journal › Journal article › Research › peer-review
Transferrin receptor-1 and ferritin heavy and light chains in astrocytic brain tumors: Expression and prognostic value
Rosager, A. M., Sørensen, M. D., Dahlrot, R. H., Hansen, S., Schonberg, D. L., Rich, J. N., Lathia, J. D. & Kristensen, Bjarne Winther, 2017, In: PLoS One. 12, 8, p. e0182954Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
Migrating glioma cells express stem cell markers and give rise to new tumors upon xenografting
Munthe, S., Sørensen, M. D., Thomassen, M., Burton, M., Kruse, T. A., Lathia, J. D., Poulsen, F. R. & Kristensen, Bjarne Winther, Oct 2016, In: Journal of Neuro-Oncology. 130, 1, p. 53-62 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Dual time-point FDG PET/CT and FDG uptake and related enzymes in lymphadenopathies: preliminary results
Christlieb, S. B., Strandholdt, C. N., Olsen, B. B., Mylam, K. J., Larsen, T. S., Nielsen, A. L., Rohde, M., Gerke, O., Olsen, K. E., Møller, M. B., Kristensen, Bjarne Winther, Abildgaard, N., Alavi, A. & Høilund-Carlsen, P. F., Sep 2016, In: European Journal of Nuclear Medicine and Molecular Imaging. 43, 10, p. 1824-36 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
Conditional ablation of myeloid TNF increases lesion volume after experimental stroke in mice, possibly via altered ERK1/2 signaling
Clausen, B. H., Degn, M., Sivasaravanaparan, M., Fogtmann, T., Andersen, M. G., Trojanowsky, M. D., Gao, H., Hvidsten, S., Baun, C., Deierborg, T., Finsen, B., Kristensen, Bjarne Winther, Bak, S. T., Meyer, M., Lee, J., Nedospasov, S. A., Brambilla, R. & Lambertsen, K. L., 7 Jul 2016, In: Scientific Reports. 6, p. 29291Research output: Contribution to journal › Journal article › Research › peer-review
Shift of microRNA profile upon orthotopic xenografting of glioblastoma spheroid cultures
Halle, B., Thomassen, M., Venkatesan, R., Kaimal, V., Marcusson, E. G., Munthe, S., Sørensen, M. D., Aaberg-Jessen, C., Jensen, S. S., Meyer, M., Kruse, T. A., Christiansen, H., Schmidt, S., Mollenhauer, J., Schulz, M. K., Andersen, C. & Kristensen, Bjarne Winther, Jul 2016, In: Journal of Neuro-Oncology. 128, 3, p. 395-404 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Widespread inflammation in CLIPPERS syndrome indicated by autopsy and ultra-high-field 7T MRI
Blaabjerg, M., Ruprecht, K., Sinnecker, T., Kondziella, D., Niendorf, T., Kerrn-Jespersen, B. M., Lindelof, M., Lassmann, H., Kristensen, Bjarne Winther, Paul, F. & Illes, Z., Jun 2016, In: Neurology: Neuroimmunology & Neuroinflammation. 3, 3, p. e226Research output: Contribution to journal › Journal article › Research › peer-review
Cell therapy centered on IL-1Ra is neuroprotective in experimental stroke
Clausen, B. H., Lambertsen, K. L., Dagnæs-Hansen, F., Babcock, A. A., von Linstow, C. U., Meldgaard, M., Kristensen, Bjarne Winther, Deierborg, T. & Finsen, B., May 2016, In: Acta Neuropathologica. 131, 5, p. 775-91 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
Expression and prognostic value of the WEE1 kinase in gliomas
Music, D., Dahlrot, R. H., Hermansen, S. K., Hjelmborg, J., de Stricker, K., Hansen, S. & Kristensen, Bjarne Winther, Apr 2016, In: Journal of Neuro-Oncology. 127, 2, p. 381-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
miR-21 Is Linked to Glioma Angiogenesis: A Co-Localization Study
Hermansen, S. K., Nielsen, B. S., Aaberg-Jessen, C. & Kristensen, Bjarne Winther, Feb 2016, In: Journal of Histochemistry and Cytochemistry. 64, 2, p. 138-48 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Convection-enhanced delivery of an anti-miR is well-tolerated, preserves anti-miR stability and causes efficient target de-repression: a proof of concept
Halle, B., Marcusson, E. G., Aaberg-Jessen, C., Jensen, S. S., Meyer, M., Schulz, M. K., Andersen, C. & Kristensen, Bjarne Winther, Jan 2016, In: Journal of Neuro-Oncology. 126, 1, p. 47-55 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Establishment and Characterization of a Tumor Stem Cell-Based Glioblastoma Invasion Model
Jensen, S. S., Meyer, M., Petterson, S. A., Halle, B., Rosager, A. M., Aaberg-Jessen, C., Thomassen, M., Burton, M., Kruse, T. A. & Kristensen, Bjarne Winther, 2016, In: PLoS One. 11, 7, p. e0159746Research output: Contribution to journal › Journal article › Research › peer-review
Expression and Prognostic Value of Oct-4 in Astrocytic Brain Tumors
Krogh Petersen, J., Jensen, P., Dahl Sørensen, M. & Kristensen, Bjarne Winther, 2016, In: PLoS One. 11, 12, p. e0169129Research output: Contribution to journal › Journal article › Research › peer-review
Glioma Cells in the Tumor Periphery Have a Stem Cell Phenotype
Munthe, S., Petterson, S. A., Dahlrot, R. H., Poulsen, F. R., Hansen, S. & Kristensen, Bjarne Winther, 2016, In: PLoS One. 11, 5, p. e0155106Research output: Contribution to journal › Journal article › Research › peer-review
Highly Effective Auger-Electron Therapy in an Orthotopic Glioblastoma Xenograft Model using Convection-Enhanced Delivery
Thisgaard, H., Halle, B., Aaberg-Jessen, C., Olsen, B. B., Therkelsen, A. S. N., Dam, J. H., Langkjær, N., Munthe, S., Någren, K., Høilund-Carlsen, P. F. & Kristensen, Bjarne Winther, 2016, In: Theranostics. 6, 12, p. 2278-2291 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
Preferential Iron Trafficking Characterizes Glioblastoma Stem-like Cells
Schonberg, D. L., Miller, T. E., Wu, Q., Flavahan, W. A., Das, N. K., Hale, J. S., Hubert, C. G., Mack, S. C., Jarrar, A. M., Karl, R. T., Rosager, A. M., Nixon, A. M., Tesar, P. J., Hamerlik, P., Kristensen, Bjarne Winther, Horbinski, C., Connor, J. R., Fox, P. L., Lathia, J. D. & Rich, J. N., 12 Oct 2015, In: Cancer Cell. 28, 4, p. 441-455 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
Estimation of Tumor Volumes by 11C-MeAIB and 18F-FDG PET in an Orthotopic Glioblastoma Rat Model
Halle, B., Thisgaard, H., Hvidsten, S., Dam, J. H., Aaberg-Jessen, C., Thykjær, A. S., Høilund-Carlsen, P. F., Schulz, M. K., Andersen, C. & Kristensen, Bjarne Winther, Oct 2015, In: Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 56, 10, p. 1562-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Systemic physiology and neuroapoptotic profiles in young and adult rats exposed to surgery: A randomized controlled study comprising four different anaesthetic techniques
Ibrahim, R. M., Krammer, C. W., Hansen, T. G., Kristensen, Bjarne Winther, Vutskits, L. & Sørensen, J. A., Oct 2015, In: International Journal of Developmental Neuroscience. 45, p. 11-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
High levels of c-Met is associated with poor prognosis in glioblastoma
Petterson, S. A., Dahlrot, R. H., Hermansen, S. K., K A Munthe, S., Gundesen, M. T., Wohlleben, H., Rasmussen, T., Beier, C. P., Hansen, S. & Kristensen, Bjarne Winther, May 2015, In: Journal of Neuro-Oncology. 122, 3, p. 517-27 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Acute hypoxia induces upregulation of microRNA-210 expression in glioblastoma spheroids
Rosenberg, T., Thomassen, M., Jensen, S. S., Larsen, M. J., Sørensen, K. P., Hermansen, S. K., Kruse, T. A. & Kristensen, Bjarne Winther, 2015, In: CNS oncology. 4, 1, p. 25-35 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Chemoresistance and chemotherapy targeting stem-like cells in malignant glioma
Sørensen, M. D., Fosmark, S., Hellwege, S., Beier, D., Kristensen, Bjarne Winther & Beier, C. P., 2015, In: Advances in Experimental Medicine and Biology. 853, p. 111-38 28 p.Research output: Contribution to journal › Review › Research › peer-review
- 2014
Novel approaches for quantifying protein biomarkers in gliomas: benefits and pitfalls
Dahlrot, R. H., Sørensen, M. D., Rosager, A. M., Hellwege, S., Bangsø, J. A., Rosenberg, T., Petterson, S. A., Klitkou, J., Fosmark, S., Hansen, S. & Kristensen, Bjarne Winther, Jul 2014, In: CNS oncology. 3, 4, p. 287-98 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Clinical value of CD133 and nestin in patients with glioma: a population-based study
Dahlrot, R. H., Hansen, S., Jensen, S. S., Schrøder, H. D., Hjelmborg, J. & Kristensen, Bjarne Winther, 2014, In: International Journal of Clinical and Experimental Pathology. 7, 7, p. 3739-51 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
Prognostic value of Musashi-1 in gliomas
Dahlrot, R. H., Hansen, S., Herrstedt, J., Schrøder, H. D., Hjelmborg, J. & Kristensen, Bjarne Winther, Dec 2013, In: Journal of Neuro-Oncology. 115, 3, p. 453-61 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Glioma spheroids obtained via ultrasonic aspiration are viable and express stem cell markers: a new tissue resource for glioma research
Jensen, S. S., Aaberg-Jessen, C., Andersen, C., Schrøder, H. D. & Kristensen, Bjarne Winther, Nov 2013, In: Neurosurgery. 73, 5, p. 868-86; discussion 886Research output: Contribution to journal › Journal article › Research › peer-review
A population-based study of low-grade gliomas and mutated isocitrate dehydrogenase 1 (IDH1)
Dahlrot, R. H., Kristensen, Bjarne Winther, Hjelmborg, J., Herrstedt, J. & Hansen, S., Sep 2013, In: Journal of Neuro-Oncology. 114, 3, p. 309-17 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 245405291
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Microglia-Secreted Factors Enhance Dopaminergic Differentiation of Tissue- and iPSC-Derived Human Neural Stem Cells
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Tumor-associated microglia and macrophages in the glioblastoma microenvironment and their implications for therapy
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Expression, prognostic significance and therapeutic implications of PD-L1 in gliomas
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