Michael Ploug
Group leader
Ploug Group
Ole Maaløes Vej 5
2200 København N.
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68Ga-labeling and in vivo evaluation of a uPAR binding DOTA- and NODAGA-conjugated peptide for PET imaging of invasive cancers
Persson, M., Madsen, J., Østergaard, S., Ploug, Michael & Kjær, Andreas, May 2012, In: Nuclear Medicine and Biology. 39, 4, p. 560-569 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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GPIHBP1 Missense Mutations Often Cause Multimerization of GPIHBP1 and Thereby Prevent Lipoprotein Lipase Binding
Beigneux, A. P., Fong, L. G., Bensadoun, A., Davies, B. S., Oberer, M., Gårdsvoll, Henrik, Ploug, Michael & Young, S. G., 2015, In: Circulation Research. 116, 4, p. 624-632 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A composite role of vitronectin and urokinase in the modulation of cell morphology upon expression of the urokinase receptor
Hillig, T., Engelholm, Lars Henning, Ingvarsen, S., Madsen, Daniel Hargbøl, Gårdsvoll, Henrik, Larsen, J. K., Ploug, Michael, Danø, K., Kjøller, L. & Behrendt, Niels, 30 May 2008, In: Journal of Biological Chemistry. 283, 22, p. 15217-15223 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A disordered acidic domain in GPIHBP1 harboring a sulfated tyrosine regulates lipoprotein lipase
Kristensen, Kristian Kølby, Midtgaard, S. R., Mysling, S., Kovrov, O., Hansen, L. B., Skar-Gislinge, Nicholas, Beigneux, A. P., Kragelund, Birthe Brandt, Olivecrona, G., Young, S. G., Jørgensen, T. J. D., Fong, L. G. & Ploug, Michael, 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 26, p. E6020-E6029 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A lipoprotein lipase (LPL)-specific monoclonal antibody, 88B8, that abolishes the binding of LPL to GPIHBP1
Allan, C. M., Larsson, M., Hu, X., He, C., Jung, R. S., Mapar, A., Voss, C., Miyashita, K., Machida, T., Murakami, M., Nakajima, K., Bensadoun, A., Ploug, Michael, Fong, L. G., Young, S. G. & Beigneux, A. P., Oct 2016, In: Journal of Lipid Research. 57, 10, p. 1889-1898Research output: Contribution to journal › Journal article › Research › peer-review
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A new tagging system for production of recombinant proteins in Drosophila S2 cells using the third domain of the urokinase receptor
Gårdsvoll, Henrik, Hansen, L. V., Jørgensen, Thomas & Ploug, Michael, Apr 2007, In: Protein Expression and Purification. 52, 2, p. 384-94 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A protein of capillary endothelial cells, GPIHBP1, is crucial for plasma triglyceride metabolism
Young, S. G., Song, W., Yang, Y., Birrane, G., Jiang, H., Beigneux, A. P., Ploug, Michael & Fong, L. G., 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 36, 12 p., e2211136119.Research output: Contribution to journal › Journal article › Research › peer-review
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A region in urokinase plasminogen receptor domain III controlling a functional association with alpha5beta1 integrin and tumor growth
Chaurasia, P., Aguirre-Ghiso, J., Liang, O. D., Gardsvoll, H., Ploug, Michael & Ossowski, L., 26 May 2006, In: The Journal of Biological Chemistry. 281, 21, p. 14852-63 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
A soluble form of the glycolipid-anchored receptor for urokinase-type plasminogen activator is secreted from peripheral blood leukocytes from patients with paroxysmal nocturnal hemoglobinuria
Ploug, Michael, Eriksen, J., Plesner, T., Hansen, N. E. & Danø, K., 1 Sep 1992, In: European Journal of Biochemistry. 208, 2, p. 397-404 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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ANGPTL4: a new mode in the regulation of intravascular lipolysis
Ploug, Michael, 2022, In: Current Opinion in Lipidology. 33, 2, p. 112-119Research output: Contribution to journal › Journal article › Research › peer-review
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ANGPTL4 inactivates lipoprotein lipase by catalyzing the irreversible unfolding of LPL's hydrolase domain
Kristensen, Kristian Kølby, Leth-Espensen, K. Z., Young, S. G. & Ploug, Michael, 2020, In: Journal of Lipid Research. 61, 9, p. 1253Research output: Contribution to journal › Journal article › Research › peer-review
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ANGPTL4 sensitizes lipoprotein lipase to PCSK3 cleavage by catalyzing its unfolding
Winther, Anne-Marie Lund, Kumari, Anni, Young, S. G. & Ploug, Michael, 2021, In: Journal of Lipid Research. 62, 2 p., 100071.Research output: Contribution to journal › Comment/debate › Research
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Administration of Recombinant Soluble Urokinase Receptor Per Se Is Not Sufficient to Induce Podocyte Alterations and Proteinuria in Mice
Cathelin, D., Placier, S., Ploug, Michael, Verpont, M., Vandermeersch, S., Luque, Y., Hertig, A., Rondeau, E. & Mesnard, L., 2014, In: Journal of the American Society of Nephrology. 25, 8, p. 1662-1668 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Altered expression of the urokinase receptor homologue, C4.4A, in invasive areas of human esophageal squamous cell carcinoma
Hansen, L. V., Laerum, O. D., Illemann, M., Nielsen, B. S. & Ploug, Michael, 15 Feb 2008, In: International Journal of Cancer. Supplement. 122, 4, p. 734-41 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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An enzyme-linked immunosorbent assay for measuring GPIHBP1 levels in human plasma or serum
Miyashita, K., Fukamachi, I., Nagao, M., Ishida, T., Kobayashi, J., Machida, T., Nakajima, K., Murakami, M., Ploug, Michael, Beigneux, A. P., Young, S. G. & Nakajima, K., Jan 2018, In: Journal of Clinical Lipidology. 12, 1, p. 203-210 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Autoantibodies against GPIHBP1 as a Cause of Hypertriglyceridemia
Beigneux, A. P., Miyashita, K., Ploug, M., Blom, J. D., Ai, M., Linton, M. F., Khovidhunkit, W., Dufour, R., Garg, A., McMahon, M. A., Pullinger, C. R., Sandoval, N. P., Hu, X., Allan, C. M., Larsson, M., Machida, T., Murakami, M., Reue, K., Tontonoz, P., Goldberg, I. J. & 5 others, , 27 Apr 2017, In: New England Journal of Medicine. 376, 17, p. 1647-1658 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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C4.4A IS A PROGNOSTIC INDICATOR IN NON-SMALL CELL LUNG CANCER PATIENTS WITH ADENOCARCINOMAS
Jacobsen, B., Muley, T., Meister, M., Dienemann, H., Christensen, I. J., Santoni Rugiu, Eric, Laerum, O. D. & Ploug, Michael, 2011, In: Journal of Thoracic Oncology.Research output: Contribution to journal › Journal article › Research › peer-review
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C4.4A as a biomarker for poor prognosis in non-small cell lung cancer patients with adenocarcinomas
Jacobsen, B., Muley, T., Meister, M., Dienemann, H., Christensen, I. J., Santoni Rugiu, Eric, Laerum, O. D. & Ploug, Michael, 2011, In: European Journal of Cancer.Research output: Contribution to journal › Journal article › Research › peer-review
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C4.4A as a biomarker in pulmonary adenocarcinoma and squamous cell carcinoma
Jacobsen, B., Kriegbaum, M. C., Santoni Rugiu, Eric & Ploug, Michael, 10 Oct 2014, In: World Journal of Clinical Oncology. 5, 4, p. 621-32 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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C4.4A er en ny biomarkør i ikke-småcellet lungekræft
Kriegbaum, M. C., Jacobsen, B., Santoni-Rugiu, E. & Ploug, Michael, 2012, In: Best Practice Onkologie. 2, 5, p. 58-61Research output: Contribution to journal › Review › Research
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C4.4A gene ablation is compatible with normal epidermal development and causes modest overt phenotypes
Kriegbaum, M. C., Jacobsen, B., Fuchtbauer, A., Hansen, Gert Helge, Christensen, I. J., Friis, Carsten, Persson, M., Engelholm, Lars Henning, Madsen, A. N., Di Meo, I., Lund, I. K., Holst, Birgitte, Kjær, Andreas, Laerum, O. D., Fuchtbauer, E. & Ploug, Michael, 12 May 2016, In: Scientific Reports. 6, 25833.Research output: Contribution to journal › Journal article › Research › peer-review
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C4.4A som biomarkør for solid tumorvækst og dårlig prognose i patienter med lungeadenokarcinom
Jacobsen, B., Santoni-Rugiu, E. & Ploug, Michael, 2014, In: Best Practice Onkologie. 4, p. 32-35Research output: Contribution to journal › Review › Research
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CL-11 circulates in serum as functionally distinct isoforms
Sutta, A., Leemans, N. N., Ploug, Michael, Rosbjerg, A., del Agua Villa, C., Pérez-Alós, L., Cyranka, L., Vincek, A. S., de Garay, T., Rivera, K. & Bayarri-Olmos, R., 2024, In: FASEB Journal. 38, 5, e23543.Research output: Contribution to journal › Journal article › Research › peer-review
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Carbohydrate as covalent crosslink in human inter-alpha-trypsin inhibitor: a novel plasma protein structure
Jessen, T. E., Faarvang, K. L. & Ploug, Michael, 28 Mar 1988, In: FEBS Letters. 230, 1-2, p. 195-200 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cell-induced potentiation of the plasminogen activation system is abolished by a monoclonal antibody that recognizes the NH2-terminal domain of the urokinase receptor
Rønne, Elsebeth, Behrendt, Niels, Ellis, V., Ploug, Michael, Danø, K. & Høyer-Hansen, G., 19 Aug 1991, In: FEBS Letters. 288, 1-2, p. 233-6 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 33978213
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Protein-binding RNA aptamers affect molecular interactions distantly from their binding sites
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Structure of the lipoprotein lipase-GPIHBP1 complex that mediates plasma triglyceride hydrolysis
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180
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IRDye800CW labeled uPAR-targeting peptide for fluorescence-guided glioblastoma surgery: Preclinical studies in orthotopic xenografts
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