Michael Ploug

Michael Ploug

Group leader


  1. 2019
  2. Published

    Structure of the lipoprotein lipase-GPIHBP1 complex that mediates plasma triglyceride hydrolysis

    Birrane, G., Beigneux, A. P., Dwyer, B., Strack-Logue, B., Kristensen, Kristian Kølby, Francone, O. L., Fong, L. G., Mertens, H. D. T., Pan, C. Q., Ploug, Michael, Young, S. G. & Meiyappan, M., 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 5, p. 1723-1732 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    The PCNA interaction motifs revisited: thinking outside the PIP-box

    Prestel, Andreas, Wichmann, N., Martins, J. M., Marabini, R., Kassem, N., Broendum, S. S., Otterlei, M., Nielsen, Olaf, Willemoës, Martin, Ploug, Michael, Boomsma, Wouter & Kragelund, Birthe Brandt, 2019, In: Cellular and Molecular Life Sciences. 76, 24, p. 4923-4943

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. 2018
  5. Published

    NanoSIMS Analysis of Intravascular Lipolysis and Lipid Movement across Capillaries and into Cardiomyocytes

    He, C., Weston, T. A., Jung, R. S., Heizer, P., Larsson, M., Hu, X., Allan, C. M., Tontonoz, P., Reue, K., Beigneux, A. P., Ploug, Michael, Holme, A., Kilburn, M., Guagliardo, P., Ford, D. A., Fong, L. G., Young, S. G. & Jiang, H., 1 May 2018, In: Cell Metabolism. 27, 5, p. 1055-1066.e3 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    An enzyme-linked immunosorbent assay for measuring GPIHBP1 levels in human plasma or serum

    Miyashita, K., Fukamachi, I., Nagao, M., Ishida, T., Kobayashi, J., Machida, T., Nakajima, K., Murakami, M., Ploug, Michael, Beigneux, A. P., Young, S. G. & Nakajima, K., Jan 2018, In: Journal of Clinical Lipidology. 12, 1, p. 203-210 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    A disordered acidic domain in GPIHBP1 harboring a sulfated tyrosine regulates lipoprotein lipase

    Kristensen, Kristian Kølby, Midtgaard, S. R., Mysling, S., Kovrov, O., Hansen, L. B., Skar-Gislinge, Nicholas, Beigneux, A. P., Kragelund, Birthe Brandt, Olivecrona, G., Young, S. G., Jørgensen, T. J. D., Fong, L. G. & Ploug, Michael, 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 26, p. E6020-E6029 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 2017
  9. Published

    Expression and crystallographic studies of the D1D2 domains of C4.4A, a homologous protein to the urokinase receptor

    Chen, S., Lin, L., Yuan, C., Gårdsvoll, Henrik, Kriegbaum, M. C., Ploug, Michael & Huang, M., 1 Aug 2017, In: Acta Crystallographica Section F: Structural Biology Communications. 73, 8, p. 486-490 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    GPIHBP1 autoantibodies in a patient with unexplained chylomicronemia

    Hu, X., Dallinga-Thie, G. M., Hovingh, G. K., Chang, S. Y., Sandoval, N. P., Dang, T. L. P., Fukamachi, I., Miyashita, K., Nakajima, K., Murakami, M., Fong, L. G., Ploug, Michael, Young, S. G. & Beigneux, A. P., 1 Jul 2017, In: Journal of Clinical Lipidology. 11, 4, p. 964-971 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Autoantibodies against GPIHBP1 as a Cause of Hypertriglyceridemia

    Beigneux, A. P., Miyashita, K., Ploug, M., Blom, J. D., Ai, M., Linton, M. F., Khovidhunkit, W., Dufour, R., Garg, A., McMahon, M. A., Pullinger, C. R., Sandoval, N. P., Hu, X., Allan, C. M., Larsson, M., Machida, T., Murakami, M., Reue, K., Tontonoz, P., Goldberg, I. J. & 5 others, Moulin, P., Charrière, S., Fong, L. G., Nakajima, K. & Young, S. G., 27 Apr 2017, In: New England Journal of Medicine. 376, 17, p. 1647-1658 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Mobility of “HSPG-bound” LPL explains how LPL is able to reach GPIHBP1 on capillaries

    Allan, C. M., Larsson, M., Jung, R. S., Ploug, Michael, Bensadoun, A., Beigneux, A. P., Fong, L. G. & Young, S. G., Jan 2017, In: Journal of Lipid Research. 58, 1, p. 216-225

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Monoclonal Antibodies That Bind to the Ly6 Domain of GPIHBP1 Abolish the Binding of LPL

    Hu, X., Sleeman, M. W., Miyashita, K., Linton, M. F., Allan, C. M., He, C., Larsson, M., Tu, Y., Sandoval, N. P., Jung, R. S., Mapar, A., Machida, T., Murakami, M., Nakajima, K., Ploug, Michael, Fong, L. G., Young, S. G. & Beigneux, A. P., Jan 2017, In: Journal of Lipid Research. 58, p. 208-215 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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