Michael Ploug

Michael Ploug

Group leader


  1. 2012
  2. Published

    Targeting tumor cell invasion and dissemination in vivo by an aptamer that inhibits urokinase-type plasminogen activator through a novel multifunctional mechanism

    Botkjaer, K. A., Deryugina, E. I., Dupont, D. M., Gårdsvoll, Henrik, Bekes, E. M., Thuesen, C. K., Chen, Z., Chen, Z., Ploug, Michael, Quigley, J. P. & Andreasen, P. A., Dec 2012, In: Molecular cancer research : MCR. 10, 12, p. 1532-43 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Hydrogen/deuterium exchange mass spectrometry reveals specific changes in the local flexibility of plasminogen activator inhibitor 1 upon binding to the somatomedin B domain of vitronectin

    Trelle, M. B., Hirschberg, D., Jansson, A., Ploug, Michael, Roepstorff, P., Andreasen, P. A. & Jørgensen, Thomas, 16 Oct 2012, In: Biochemistry. 51, 41, p. 8256-66 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    New peptide receptor radionuclide therapy of invasive cancer cells: in vivo studies using 177Lu-DOTA-AE105 targeting uPAR in human colorectal cancer xenografts

    Persson, M., Rasmussen, P., Madsen, J., Ploug, Michael & Kjær, Andreas, Oct 2012, In: Nuclear Medicine and Biology. 39, 7, p. 962-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Erratum: Crystal structure of the urokinase receptor in a ligand-free form (Journal of Molecular Biology (2012) 416 (629-641))

    Xu, X., Gårdsvoll, Henrik, Yuan, C., Lin, L., Ploug, Michael & Huang, M., 7 Sep 2012, In: Journal of Molecular Biology. 422, 1, 1 p.

    Research output: Contribution to journalComment/debateResearch

  6. Published

    Expression of C4.4A in precursor lesions of pulmonary adenocarcinoma and squamous cell carcinoma

    Jacobsen, B., Santoni Rugiu, Eric, Illemann, M., Kriegbaum, M. C., Laerum, O. D. & Ploug, Michael, 1 Jun 2012, In: International journal of cancer. Journal international du cancer. 130, 11, p. 2734-9 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    68Ga-labeling and in vivo evaluation of a uPAR binding DOTA- and NODAGA-conjugated peptide for PET imaging of invasive cancers

    Persson, M., Madsen, J., Østergaard, S., Ploug, Michael & Kjær, Andreas, May 2012, In: Nuclear Medicine and Biology. 39, 4, p. 560-569 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Crystal structure of the urokinase receptor in a ligand-free form

    Xu, X., Gårdsvoll, Henrik, Yuan, C., Lin, L., Ploug, Michael & Huang, M., 9 Mar 2012, In: Journal of Molecular Biology. 416, 5, p. 629-41 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    C4.4A er en ny biomarkør i ikke-småcellet lungekræft

    Kriegbaum, M. C., Jacobsen, B., Santoni-Rugiu, E. & Ploug, Michael, 2012, In: Best Practice Onkologie. 2, 5, p. 58-61

    Research output: Contribution to journalReviewResearch

  10. Published

    Quantitative PET of human urokinase-type plasminogen activator receptor with 64Cu-DOTA-AE105: implications for visualizing cancer invasion

    Persson, M., Madsen, J., Østergaard, S., Wessel, Mette Munk, Jørgensen, Jesper Tranekjær, Stræde, Karina, Lehmann, C., Ploug, Michael & Kjær, Andreas, 2012, In: Journal of Nuclear Medicine. 53, 1, p. 138-45 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Urokinase-type plasminogen activator-like proteases in teleosts lack genuine receptor-binding epidermal growth factor-like domains

    Bager, R., Kristensen, T. K., Jensen, J., Szczur, A., Christensen, A., Andersen, L., Johansen, J. S., Larsen, N., Baatrup, E., Huang, M., Ploug, Michael & Andreasen, P. A., 2012, In: The Journal of Biological Chemistry. 287, 33, p. 27526-27536 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 33978213