Vectors and methods for recombinant production of uPA-binding fragments of the human urokinase-type plasminogen receptor (uPAR)
Research output: Patent
Activation of plasminogen to plasma is inhibited by preventing the binding of a receptor binding form of urokinase-type plasminogen activator to a urokinase-type plasminogen activator receptor in a mammal, thereby preventing the urokinase-type plasminogen activator from converting plasminogen into plasmin. DNA fragments which encode for soluble, active fragments of the urokinase-type plasminogen activator are provided.
| Original language | English |
|---|---|
| IPC | A61K 38/ 00 A N |
| Patent number | US5891664 |
| Country/Territory | Denmark |
| Priority date | 06/10/1994 |
| Priority number | US19940319052 |
| Publication status | Published - 6 Apr 1999 |
ID: 178221407