Michael Ploug

Michael Ploug

Group leader

ORCID: 0000-0003-2215-4265

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  1. Published

    Heterogeneity in the properties of mutant secreted lymphocyte antigen 6/urokinase receptor-related protein 1 (SLURP1) in Mal de Meleda

    Adeyo, O., Oberer, M., Ploug, Michael, Fong, L. G., Young, S. G. & Beigneux, A. P., Oct 2015, In: British Journal of Dermatology. 173, 4, p. 1066-9 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    A lipoprotein lipase (LPL)-specific monoclonal antibody, 88B8, that abolishes the binding of LPL to GPIHBP1

    Allan, C. M., Larsson, M., Hu, X., He, C., Jung, R. S., Mapar, A., Voss, C., Miyashita, K., Machida, T., Murakami, M., Nakajima, K., Bensadoun, A., Ploug, Michael, Fong, L. G., Young, S. G. & Beigneux, A. P., Oct 2016, In: Journal of Lipid Research. 57, 10, p. 1889-1898

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Mobility of “HSPG-bound” LPL explains how LPL is able to reach GPIHBP1 on capillaries

    Allan, C. M., Larsson, M., Jung, R. S., Ploug, Michael, Bensadoun, A., Beigneux, A. P., Fong, L. G. & Young, S. G., Jan 2017, In: Journal of Lipid Research. 58, 1, p. 216-225

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Tissue Inhibitor of Metalloproteinase-1 Is Confined to Tumor-Associated Myofibroblasts and Is Increased With Progression in Gastric Adenocarcinoma

    Alpízar-Alpízar, W., Lærum, O. D., Christensen, I. J., Ovrebo, K., Skarstein, A., Høyer-Hansen, G., Ploug, Michael & Illemann, M., Aug 2016, In: Journal of Histochemistry and Cytochemistry. 64, 8, p. 483-94 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Helicobacter pylori Colonization Drives Urokinase Receptor (uPAR) Expression in Murine Gastric Epithelium During Early Pathogenesis

    Alpízar-Alpízar, W., Skindersoe, M. E., Rasmussen, L., Kriegbaum, M. C., Christensen, I. J., Lund, I. K., Illemann, M., Laerum, O. D., Krogfelt, K. A., Andersen, L. P. & Ploug, Michael, 2020, In: Microorganisms. 8, 7, 1019.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Proteasernes veje og vildveje

    Andreasen, P., Kjaer, A., Persson, M. & Ploug, Michael, 2011, In: Aktuel Naturvidenskab. 6, p. 24-27

    Research output: Contribution to journal › Review › Research

  7. Published

    Intermittent chylomicronemia caused by intermittent GPIHBP1 autoantibodies

    Ashraf, A. P., Miyashita, K., Nakajima, K., Murakami, M., Hegele, R. A., Ploug, Michael, Fong, L. G., Young, S. G. & Beigneux, A. P., 2020, In: Journal of Clinical Lipidology. 14, 2, p. 197-200

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Specific recognition of the C-terminal end of A beta 42 by a high affinity monoclonal antibody

    Axelsen, T. V., Holm, A., Birkelund, S., Christiansen, G., Ploug, Michael & Holm, I. E., Jul 2009, In: Molecular Immunology. 46, 11-12, p. 2267-73 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Hydrogen atom scrambling in selectively labeled anionic peptides upon collisional activation by MALDI tandem time-of-flight mass spectrometry

    Bache, N., Rand, Kasper Dyrberg, Roepstorff, P., Ploug, Michael & Jørgensen, T., 2008, In: Journal of The American Society for Mass Spectrometry. 19, 12, p. 1719-25 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Urokinase-type plasminogen activator-like proteases in teleosts lack genuine receptor-binding epidermal growth factor-like domains

    Bager, R., Kristensen, T. K., Jensen, J., Szczur, A., Christensen, A., Andersen, L., Johansen, J. S., Larsen, N., Baatrup, E., Huang, M., Ploug, Michael & Andreasen, P. A., 2012, In: The Journal of Biological Chemistry. 287, 33, p. 27526-27536 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Cellular receptor for urokinase-type plasminogen activator: protein structure

    Behrendt, Niels, Ploug, Michael, Rønne, Elsebeth, Høyer-Hansen, G. & Danø, K., 1993, Methods of Enzymology. Vol. 223. p. 207-22 16 p. (Methods in Enzymology).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  12. Published

    Localization and functional significance of a polymorphic determinant in the third component of human complement

    Behrendt, Niels, Hansen, Ole, Ploug, Michael, Barkholt, V. & Koch, C., Oct 1987, In: Molecular Immunology. 24, 10, p. 1097-103 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. The human receptor for urokinase plasminogen activator. NH2-terminal amino acid sequence and glycosylation variants

    Behrendt, Niels, Rønne, Elsebeth, Ploug, Michael, Petri, T., Løber, D., Nielsen, L. S., Schleuning, W. D., Blasi, F., Appella, E. & Danø, K., 15 Apr 1990, In: The Journal of Biological Chemistry. 265, 11, p. 6453-60 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Autoantibodies against GPIHBP1 as a Cause of Hypertriglyceridemia

    Beigneux, A. P., Miyashita, K., Ploug, M., Blom, J. D., Ai, M., Linton, M. F., Khovidhunkit, W., Dufour, R., Garg, A., McMahon, M. A., Pullinger, C. R., Sandoval, N. P., Hu, X., Allan, C. M., Larsson, M., Machida, T., Murakami, M., Reue, K., Tontonoz, P., Goldberg, I. J. & 5 others, Moulin, P., Charrière, S., Fong, L. G., Nakajima, K. & Young, S. G., 27 Apr 2017, In: New England Journal of Medicine. 376, 17, p. 1647-1658 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Lipoprotein lipase is active as a monomer

    Beigneux, A. P., Allan, C. M., Sandoval, N. P., Cho, G. W., Heizer, P. J., Jung, R. S., Stanhope, K. L., Havel, P. J., Birrane, G., Meiyappan, M., Gill, J. E., Murakami, M., Miyashita, K., Nakajima, K., Ploug, Michael, Fong, L. G. & Young, S. G., 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 13, p. 6319-6328 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    GPIHBP1 Missense Mutations Often Cause Multimerization of GPIHBP1 and Thereby Prevent Lipoprotein Lipase Binding

    Beigneux, A. P., Fong, L. G., Bensadoun, A., Davies, B. S., Oberer, M., Gårdsvoll, Henrik, Ploug, Michael & Young, S. G., 2015, In: Circulation Research. 116, 4, p. 624-632 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Structure of the lipoprotein lipase-GPIHBP1 complex that mediates plasma triglyceride hydrolysis

    Birrane, G., Beigneux, A. P., Dwyer, B., Strack-Logue, B., Kristensen, Kristian Kølby, Francone, O. L., Fong, L. G., Mertens, H. D. T., Pan, C. Q., Ploug, Michael, Young, S. G. & Meiyappan, M., 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 5, p. 1723-1732 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. The urokinase receptor and regulation of cell surface plasminogen activation

    Blasi, F., Cubellis, M. V., Masucci, M. T., Møller, L. B., Olson, D. P., Pedersen, N., Behrendt, Niels, Ellis, V., Ploug, Michael, Rønne, E. & Danø, K., 1990, In: Cell Differentation and Development. 32, 3, p. 247-54

    Research output: Contribution to journal › Journal article › Research

  19. Published

    Interactions of plasminogen activator inhibitor-1 with vitronectin involve an extensive binding surface and induce mutual conformational rearrangements

    Blouse, G. E., Dupont, D. M., Schar, C. R., Jensen, J. K., Minor, K. H., Anagli, J. Y., Gårdsvoll, Henrik, Ploug, Michael, Peterson, C. B. & Andreasen, P. A., 3 Mar 2009, In: Biochemistry. 48, 8, p. 1723-35 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Targeting tumor cell invasion and dissemination in vivo by an aptamer that inhibits urokinase-type plasminogen activator through a novel multifunctional mechanism

    Botkjaer, K. A., Deryugina, E. I., Dupont, D. M., Gårdsvoll, Henrik, Bekes, E. M., Thuesen, C. K., Chen, Z., Chen, Z., Ploug, Michael, Quigley, J. P. & Andreasen, P. A., Dec 2012, In: Molecular cancer research : MCR. 10, 12, p. 1532-43 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Administration of Recombinant Soluble Urokinase Receptor Per Se Is Not Sufficient to Induce Podocyte Alterations and Proteinuria in Mice

    Cathelin, D., Placier, S., Ploug, Michael, Verpont, M., Vandermeersch, S., Luque, Y., Hertig, A., Rondeau, E. & Mesnard, L., 2014, In: Journal of the American Society of Nephrology. 25, 8, p. 1662-1668 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Origin and diversification of the plasminogen activation system among chordates

    Chana-Muñoz, A., Jendroszek, A., Sønnichsen, M., Wang, T., Ploug, Michael, Jensen, J. K., Andreasen, P. A., Bendixen, C. & Panitz, F., 2019, In: BMC Evolutionary Biology. 19, 1, p. 1-17 17 p., 27.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    A region in urokinase plasminogen receptor domain III controlling a functional association with alpha5beta1 integrin and tumor growth

    Chaurasia, P., Aguirre-Ghiso, J., Liang, O. D., Gardsvoll, H., Ploug, Michael & Ossowski, L., 26 May 2006, In: The Journal of Biological Chemistry. 281, 21, p. 14852-63 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Expression and crystallographic studies of the D1D2 domains of C4.4A, a homologous protein to the urokinase receptor

    Chen, S., Lin, L., Yuan, C., Gårdsvoll, Henrik, Kriegbaum, M. C., Ploug, Michael & Huang, M., 1 Aug 2017, In: Acta Crystallographica Section F: Structural Biology Communications. 73, 8, p. 486-490 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Selective abrogation of the uPA-uPAR interaction in vivo reveals a novel role in suppression of fibrin-associated inflammation

    Connolly, B. M., Choi, E. Y., Gårdsvoll, Henrik, Bey, A. L., Currie, B. M., Chavakis, T., Liu, S., Molinolo, A., Ploug, Michael, Leppla, S. H. & Bugge, T. V., 2 Sep 2010, In: Blood Weekly. 116, 9, p. 1593-603 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 33978213