Michael Ploug

Michael Ploug

Group leader

ORCID: 0000-0003-2215-4265

Publication year:
All
101 - 125 out of 171Page size: 25
  1. 2010
  2. Published

    Structure-based engineering of species selectivity in the interaction between urokinase and its receptor: implication for preclinical cancer therapy

    Lin, L., Gårdsvoll, Henrik, Huai, Q., Huang, M. & Ploug, Michael, 2 Apr 2010, In: Journal of Biological Chemistry. 285, 14, p. 10982-92 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. 2009
  4. Published

    Specific recognition of the C-terminal end of A beta 42 by a high affinity monoclonal antibody

    Axelsen, T. V., Holm, A., Birkelund, S., Christiansen, G., Ploug, Michael & Holm, I. E., Jul 2009, In: Molecular Immunology. 46, 11-12, p. 2267-73 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Interactions of plasminogen activator inhibitor-1 with vitronectin involve an extensive binding surface and induce mutual conformational rearrangements

    Blouse, G. E., Dupont, D. M., Schar, C. R., Jensen, J. K., Minor, K. H., Anagli, J. Y., Gårdsvoll, Henrik, Ploug, Michael, Peterson, C. B. & Andreasen, P. A., 3 Mar 2009, In: Biochemistry. 48, 8, p. 1723-35 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Expression of C4.4A in precursor lesions of non-small cell lung cancer

    Jacobsen, B., Santoni Rugiu, Eric, Illemann, M., Laerum, O. D. & Ploug, Michael, 2009, In: Journal of Thoracic Oncology.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. PLAUR (Plasminogen activator, urokinase receptor

    Jacobsen, B., Illemann, M. & Ploug, Michael, 2009

    Research output: Other contribution › Net publication - Internet publication › Research › peer-review

  8. 2008
  9. Published

    Imaging of urokinase-type plasminogen activator receptor expression using a 64Cu-labeled linear peptide antagonist by microPET

    Li, Z., Niu, G., Wang, H., He, L., Yang, L., Ploug, Michael & Chen, X., 1 Aug 2008, In: Clinical Cancer Research. 14, 15, p. 4758-66 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    A composite role of vitronectin and urokinase in the modulation of cell morphology upon expression of the urokinase receptor

    Hillig, T., Engelholm, Lars Henning, Ingvarsen, S., Madsen, Daniel Hargbøl, Gårdsvoll, Henrik, Larsen, J. K., Ploug, Michael, Danø, K., Kjøller, L. & Behrendt, Niels, 30 May 2008, In: Journal of Biological Chemistry. 283, 22, p. 15217-15223 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Altered expression of the urokinase receptor homologue, C4.4A, in invasive areas of human esophageal squamous cell carcinoma

    Hansen, L. V., Laerum, O. D., Illemann, M., Nielsen, B. S. & Ploug, Michael, 15 Feb 2008, In: International Journal of Cancer. Supplement. 122, 4, p. 734-41 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Hydrogen atom scrambling in selectively labeled anionic peptides upon collisional activation by MALDI tandem time-of-flight mass spectrometry

    Bache, N., Rand, Kasper Dyrberg, Roepstorff, P., Ploug, Michael & Jørgensen, T., 2008, In: Journal of The American Society for Mass Spectrometry. 19, 12, p. 1719-25 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. LYPD3 (LY6/PLAUR domain containing 3

    Jacobsen, B. & Ploug, Michael, 2008

    Research output: Other contribution › Net publication - Internet publication › Research › peer-review

  14. Structure and inhibition of the urokinase-type plasminogen activator receptor(uPAR)

    Jacobsen, B., Kjaergaard, M., Gårdsvoll, H. & Ploug, Michael, 2008, The Cancer Degradome: Proteases and Cancer Biology. Edwards, D., Høyer-Hansen, G., Blasi, F. & Sloane, B. L. (eds.). Springer Verlag, p. 699-719

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  15. Published

    Structure and ligand interactions of the urokinase receptor (uPAR)

    Kjærgaard, M., Hansen, L. V., Jacobsen, B., Gårdsvoll, H. & Ploug, Michael, 2008, In: Frontiers in Bioscience. 13, p. 5441-5461 21 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    The urokinase receptor and its structural homologue C4.4A in human cancer: expression, prognosis and pharmacological inhibition

    Jacobsen, B. & Ploug, Michael, 2008, In: Current Medicinal Chemistry. 15, 25, p. 2559-73 15 p.

    Research output: Contribution to journal › Review › Research › peer-review

  17. 2007
  18. Published

    Tumour cell expression of C4.4A, a structural homologue of the urokinase receptor, correlates with poor prognosis in non-small cell lung cancer

    Hansen, L. V., Skov, B. G., Ploug, Michael & Pappot, Helle, Nov 2007, In: Lung Cancer. 58, 2, p. 260-6 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Mapping of the vitronectin-binding site on the urokinase receptor: involvement of a coherent receptor interface consisting of residues from both domain I and the flanking interdomain linker region

    Gårdsvoll, Henrik & Ploug, Michael, 4 May 2007, In: The Journal of Biological Chemistry. 282, 18, p. 13561-72 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    A new tagging system for production of recombinant proteins in Drosophila S2 cells using the third domain of the urokinase receptor

    Gårdsvoll, Henrik, Hansen, L. V., Jørgensen, Thomas & Ploug, Michael, Apr 2007, In: Protein Expression and Purification. 52, 2, p. 384-94 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. One-step affinity purification of recombinant urokinase-type plasminogen activator receptor using a synthetic peptide developed by combinatorial chemistry

    Jacobsen, B., Gårdsvoll, Henrik, Juhl Funch, G., Ostergaard, S., Barkholt, V. & Ploug, Michael, Apr 2007, In: Protein Expression and Purification. 52, 2, p. 286-96 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. 2006
  23. Published

    Characterization of the functional epitope on the urokinase receptor. Complete alanine scanning mutagenesis supplemented by chemical cross-linking

    Gårdsvoll, Henrik, Gilquin, B., Le Du, M. H., Ménèz, A., Jørgensen, Thomas & Ploug, Michael, 14 Jul 2006, In: The Journal of Biological Chemistry. 281, 28, p. 19260-72 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    A region in urokinase plasminogen receptor domain III controlling a functional association with alpha5beta1 integrin and tumor growth

    Chaurasia, P., Aguirre-Ghiso, J., Liang, O. D., Gardsvoll, H., Ploug, Michael & Ossowski, L., 26 May 2006, In: The Journal of Biological Chemistry. 281, 21, p. 14852-63 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Peptide antagonists of the human urokinase receptor and method for selecting them

    Ploug, Michael, Oestergaard, S., Holst-Hansen, C., Stephens, R., Danoe, K. & Holm, A., 11 Apr 2006, IPC No. A61K 38/ 00 A N, Patent No. US7026282, Priority date 1 Jul 1999, Priority No. WO1999DK00377

    Research output: Patent

  26. Plasminogen activation independent of uPA and tPA maintains wound healing in gene-deficient mice

    Lund, L. R., Green, K. A., Stoop, A. A., Ploug, Michael, Almholt, K., Lilla, J., Nielsen, B. S., Christensen, I. J., Craik, C. S., Werb, Z., Danø, K. & Rømer, J., 2006, In: EMBO Journal. 25, 12, p. 2686-97 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. 2005
  28. Published

    Collisional activation by MALDI tandem time-of-flight mass spectrometry induces intramolecular migration of amide hydrogens in protonated peptides

    Jørgensen, Thomas, Bache, N., Roepstorff, P., Gårdsvoll, Henrik & Ploug, Michael, Dec 2005, In: Molecular and Cellular Proteomics. 4, 12, p. 1910-9 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Crystal structure of the human urokinase plasminogen activator receptor bound to an antagonist peptide

    Llinas, P., Le Du, M. H., Gårdsvoll, Henrik, Danø, K., Ploug, Michael, Gilquin, B., Stura, E. A. & Ménèz, A., 4 May 2005, In: E M B O Journal. 24, 9, p. 1655-63 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Intramolecular migration of amide hydrogens in protonated peptides upon collisional activation

    Jørgensen, Thomas, Gårdsvoll, Henrik, Ploug, Michael & Roepstorff, P., 2 Mar 2005, In: Journal of the American Chemical Society. 127, 8, p. 2785-93 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Plasminogen activation and cancer

    Danø, K., Behrendt, N., Hoyer-Hansen, G., Johnsen, M., Lund, L. R., Ploug, Michael & Nielsen, J. R., 2005, In: Thrombosis and Haemostasis. 93, 4, p. 676-681 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 33978213