Jesper Bøje Andersen

Jesper Bøje Andersen

Professor

ORCID: 0000-0003-1760-5244

Publication year:
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  1. 2004

  2. Interaction between the 2'-5' oligoadenylate synthetase-like protein p59 OASL and the transcriptional repressor methyl CpG-binding protein 1

    Andersen, Jesper Bøje, Strandbygård, D. J., Hartmann, R. & Justesen, J., Feb 2004, In: European Journal of Biochemistry. 271, 3, p. 628-36 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. 2006

  4. Stage-associated overexpression of the ubiquitin-like protein, ISG15, in bladder cancer

    Andersen, Jesper Bøje, Aaboe, M., Borden, E. C., Goloubeva, O. G., Hassel, B. A. & Orntoft, T. F., 22 May 2006, In: B J C. 94, 10, p. 1465-71 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. The interferon regulated ubiquitin-like protein, ISG15, in tumorigenesis: friend or foe?

    Andersen, Jesper Bøje & Hassel, B. A., Dec 2006, In: Cytokine & Growth Factor Reviews. 17, 6, p. 411-21 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

  6. 2007

  7. Post-transcriptional regulation of RNase-L expression is mediated by the 3'-untranslated region of its mRNA

    Li, X., Andersen, Jesper Bøje, Ezelle, H. J., Wilson, G. M. & Hassel, B. A., 16 Mar 2007, In: The Journal of Biological Chemistry. 282, 11, p. 7950-60 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Role of 2-5A-dependent RNase-L in senescence and longevity

    Andersen, Jesper Bøje, Li, X. L., Judge, C. S., Zhou, A., Jha, B. K., Shelby, S., Zhou, L., Silverman, R. H. & Hassel, B. A., 10 May 2007, In: Oncogene. 26, 21, p. 3081-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. 2008

  10. UBE1L causes lung cancer growth suppression by targeting cyclin D1

    Feng, Q., Sekula, D., Guo, Y., Liu, X., Black, C. C., Galimberti, F., Shah, S. J., Sempere, L. F., Memoli, V., Andersen, Jesper Bøje, Hassel, B. A., Dragnev, K. & Dmitrovsky, E., Dec 2008, In: Molecular Cancer Therapeutics. 7, 12, p. 3780-8 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. 2009

  12. Ribosomal protein mRNAs are primary targets of regulation in RNase-L-induced senescence

    Andersen, Jesper Bøje, Mazan-Mamczarz, K., Zhan, M., Gorospe, M. & Hassel, B. A., 2009, In: RNA Biology. 6, 3, p. 305-15 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Loss of miR-122 expression in liver cancer correlates with suppression of the hepatic phenotype and gain of metastatic properties

    Coulouarn, C., Factor, V. M., Andersen, Jesper Bøje, Durkin, M. E. & Thorgeirsson, S. S., 8 Oct 2009, In: Oncogene. 28, 40, p. 3526-36 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. 2010

  15. Loss of c-Met disrupts gene expression program required for G2/M progression during liver regeneration in mice

    Factor, V. M., Seo, D., Ishikawa, T., Kaposi-Novak, P., Marquardt, J. U., Andersen, Jesper Bøje, Conner, E. A. & Thorgeirsson, S. S., 2010, In: PLOS ONE. 5, 9

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Progenitor-derived hepatocellular carcinoma model in the rat

    Andersen, Jesper Bøje, Loi, R., Perra, A., Factor, V. M., Ledda-Columbano, G. M., Columbano, A. & Thorgeirsson, S. S., Apr 2010, In: Hepatology. 51, 4, p. 1401-9 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. An integrated genomic and epigenomic approach predicts therapeutic response to zebularine in human liver cancer

    Andersen, Jesper Bøje, Factor, V. M., Marquardt, J. U., Raggi, C., Lee, Y., Seo, D., Conner, E. A. & Thorgeirsson, S. S., 20 Oct 2010, In: Science Translational Medicine. 2, 54, p. 54ra77

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Definition of ubiquitination modulator COP1 as a novel therapeutic target in human hepatocellular carcinoma

    Lee, Y., Andersen, Jesper Bøje, Song, H., Judge, A. D., Seo, D., Ishikawa, T., Marquardt, J. U., Kitade, M., Durkin, M. E., Raggi, C., Woo, H. G., Conner, E. A., Avital, I., Maclachlan, I., Factor, V. M. & Thorgeirsson, S. S., 1 Nov 2010, In: Cancer Research. 70, 21, p. 8264-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. 2011

  20. Coactivation of AKT and β-catenin in mice rapidly induces formation of lipogenic liver tumors

    Stauffer, J. K., Scarzello, A. J., Andersen, Jesper Bøje, De Kluyver, R. L., Back, T. C., Weiss, J. M., Thorgeirsson, S. S. & Wiltrout, R. H., 1 Apr 2011, In: Cancer Research. 71, 7, p. 2718-27 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Human hepatic cancer stem cells are characterized by common stemness traits and diverse oncogenic pathways

    Marquardt, J. U., Raggi, C., Andersen, Jesper Bøje, Seo, D., Avital, I., Geller, D., Lee, Y., Kitade, M., Holczbauer, A., Gillen, M. C., Conner, E. A., Factor, V. M. & Thorgeirsson, S. S., 2 Sep 2011, In: Hepatology. 54, 3, p. 1031-42 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Notch signaling inhibits hepatocellular carcinoma following inactivation of the RB pathway

    Viatour, P., Ehmer, U., Saddic, L. A., Dorrell, C., Andersen, Jesper Bøje, Lin, C., Zmoos, A., Mazur, P. K., Schaffer, B. E., Ostermeier, A., Vogel, H., Sylvester, K. G., Thorgeirsson, S. S., Grompe, M. & Sage, J., 26 Sep 2011, In: The Journal of Experimental Medicine. 208, 10, p. 1963-76 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Molecular targeting of CSN5 in human hepatocellular carcinoma: a mechanism of therapeutic response

    Lee, Y., Judge, A. D., Seo, D., Kitade, M., Gómez-Quiroz, L. E., Ishikawa, T., Andersen, Jesper Bøje, Kim, B., Marquardt, J. U., Raggi, C., Avital, I., Conner, E. A., MacLachlan, I., Factor, V. M. & Thorgeirsson, S. S., 6 Oct 2011, In: Oncogene. 30, 40, p. 4175-84 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. 2012

  25. Genomic and genetic characterization of cholangiocarcinoma identifies therapeutic targets for tyrosine kinase inhibitors

    Andersen, Jesper Bøje, Spee, B., Blechacz, B. R., Avital, I., Komuta, M., Barbour, A., Conner, E. A., Gillen, M. C., Roskams, T., Roberts, L. R., Factor, V. M. & Thorgeirsson, S. S., Apr 2012, In: Gastroenterology. 142, 4, p. 1021-1031.e15

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Genetic profiling of intrahepatic cholangiocarcinoma

    Andersen, Jesper Bøje & Thorgeirsson, S. S., May 2012, In: Current Opinion in Gastroenterology. 28, 3, p. 266-72 7 p.

    Research output: Contribution to journal › Review › Research › peer-review

  27. mTOR inhibitors synergize on regression, reversal of gene expression, and autophagy in hepatocellular carcinoma

    Thomas, H. E., Mercer, C. A., Carnevalli, L. S., Park, J., Andersen, Jesper Bøje, Conner, E. A., Tanaka, K., Matsutani, T., Iwanami, A., Aronow, B. J., Manway, L., Maira, S. M., Thorgeirsson, S. S., Mischel, P. S., Thomas, G. & Kozma, S. C., 20 Jun 2012, In: Science Translational Medicine. 4, 139, p. 139ra84

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Next-Generation Sequencing: Application in Liver Cancer-Past, Present and Future?

    Marquardt, J. U. & Andersen, Jesper Bøje, 31 Aug 2012, In: Biology. 1, 2, p. 383-394 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Transcriptomic profiling reveals hepatic stem-like gene signatures and interplay of miR-200c and epithelial-mesenchymal transition in intrahepatic cholangiocarcinoma

    Oishi, N., Kumar, M. R., Roessler, S., Ji, J., Forgues, M., Budhu, A., Zhao, X., Andersen, Jesper Bøje, Ye, Q., Jia, H., Qin, L., Yamashita, T., Woo, H. G., Kim, Y. J., Kaneko, S., Tang, Z., Thorgeirsson, S. S. & Wang, X. W., Nov 2012, In: Hepatology. 56, 5, p. 1792-803 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. 2013
  31. Published

    Molecular constituents of the extracellular matrix in rat liver mounting a hepatic progenitor cell response for tissue repair

    Vestentoft, P. S., Jelnes, P., Andersen, Jesper Bøje, Tran, T. A. T., Jørgensen, T., Rasmussen, M., Lange, Jette Bornholdt, Grøvdal, L. M., Jensen, C. H., Vogel, Lotte, Thorgeirsson, S. S. & Bisgaard, Hanne Cathrine, 2013, In: Fibrogenesis & Tissue Repair. 6, 1, 15 p., 21.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Genomic decoding of intrahepatic cholangiocarcinoma reveals therapeutic opportunities

    Andersen, Jesper Bøje & Thorgeirsson, S. S., Apr 2013, In: Gastroenterology. 144, 4, p. 687-90 4 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  33. Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas

    Wang, P., Dong, Q., Zhang, C., Kuan, P-F., Liu, Y., Jeck, W. R., Andersen, J. B., Jiang, W., Savich, G. L., Tan, T-X., Auman, J. T., Hoskins, J. M., Misher, A. D., Moser, C. D., Yourstone, S. M., Kim, J. W., Cibulskis, K., Getz, G., Hunt, H. V., Thorgeirsson, S. S. & 6 others, Roberts, L. R., Ye, D., Guan, K., Xiong, Y., Qin, L. & Chiang, D. Y., 20 Jun 2013, In: Oncogene. 32, 25, p. 3091-100 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Modeling pathogenesis of primary liver cancer in lineage-specific mouse cell types

    Holczbauer, A., Factor, V. M., Andersen, Jesper Bøje, Marquardt, J. U., Kleiner, D. E., Raggi, C., Kitade, M., Seo, D., Akita, H., Durkin, M. E. & Thorgeirsson, S. S., Jul 2013, In: Gastroenterology. 145, 1, p. 221-31 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Specific fate decisions in adult hepatic progenitor cells driven by MET and EGFR signaling

    Kitade, M., Factor, V. M., Andersen, Jesper Bøje, Tomokuni, A., Kaji, K., Akita, H., Holczbauer, A., Seo, D., Marquardt, J. U., Conner, E. A., Lee, S., Lee, Y. & Thorgeirsson, S. S., 1 Aug 2013, In: Genes & Development. 27, 15, p. 1706-17 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Targeting the mTOR pathway in hepatocellular carcinoma: Current state and future trends

    Matter, M. S., Decaens, T., Andersen, Jesper Bøje & Thorgeirsson, S. S., 3 Dec 2013, In: Journal of Hepatology.

    Research output: Contribution to journal › Review › Research › peer-review

  37. 2014
  38. Published

    A perspective on molecular therapy in cholangiocarcinoma: present status and future directions

    Andersen, Jesper Bøje & Thorgeirsson, S. S., 2014, In: Hepatic Oncology. 1, 1, p. 143-157 15 p.

    Research output: Contribution to journal › Review › Research › peer-review

  39. Long noncoding RNA HOTTIP/HOXA13 expression is associated with disease progression and predicts outcome in hepatocellular carcinoma patients

    Quagliata, L., Matter, M. S., Piscuoglio, S., Arabi, L., Ruiz, C., Procino, A., Kovac, M., Moretti, F., Makowska, Z., Boldanova, T., Andersen, Jesper Bøje, Hämmerle, M., Tornillo, L., Heim, M. H., Diederichs, S., Cillo, C. & Terracciano, L. M., 2014, In: Hepatology. 59, 3, p. 911-923

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Epigenetic reprogramming modulates malignant properties of human liver cancer

    Raggi, C., Factor, V. M., Seo, D., Holczbauer, A., Gillen, M. C., Marquardt, J. U., Andersen, Jesper Bøje, Durkin, M. & Thorgeirsson, S. S., 21 Jan 2014, In: Hepatology.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Sequential transcriptome analysis of human liver cancer indicates late stage acquisition of malignant traits

    Marquardt, J. U., Seo, D., Andersen, Jesper Bøje, Gillen, M. C., Kim, M. S., Conner, E. A., Galle, P. R., Factor, V. M., Park, Y. N. & Thorgeirsson, S. S., Feb 2014, In: Journal of Hepatology. 60, 2, p. 346-53 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Antitumor effects in hepatocarcinoma of isoform-selective inhibition of HDAC2

    Lee, Y., Seo, D., Choi, K., Andersen, Jesper Bøje, Won, M., Kitade, M., Gomez-Quiroz, L. E., Judge, A. D., Marquardt, J. U., Raggi, C., Conner, E. A., MacLachlan, I., Factor, V. M. & Thorgeirsson, S., 23 Jun 2014, In: Cancer Research. 74, 17, p. 4752-4761 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    p53-Dependent Nestin Regulation Links Tumor Suppression to Cellular Plasticity in Liver Cancer

    Tschaharganeh, D. F., Xue, W., Calvisi, D. F., Evert, M., Michurina, T. V., Dow, L. E., Banito, A., Katz, S. F., Kastenhuber, E. R., Weissmueller, S., Huang, C., Lechel, A., Andersen, Jesper Bøje, Capper, D., Zender, L., Longerich, T., Enikolopov, G. & Lowe, S. W., 31 Jul 2014, In: Cell. 158, 3, p. 579-92 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Molecular pathogenesis of intrahepatic cholangiocarcinoma

    Andersen, Jesper Bøje, 1 Sep 2014, In: Journal of Hepato - Biliary - Pancreatic Sciences.

    Research output: Contribution to journal › Review › Research › peer-review

  45. Published

    MYC activates stem-like cell potential in hepatocarcinoma by a p53-dependent mechanism

    Akita, H., Marquardt, J. U., Durkin, M. E., Kitade, M., Seo, D., Conner, E. A., Andersen, Jesper Bøje, Factor, V. M. & Thorgeirsson, S. S., 4 Sep 2014, In: Cancer Research.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Impact of Microenvironment and Stem-Like Plasticity in Cholangiocarcinoma: Molecular Networks and Biological Concepts

    Raggi, C., Invernizzi, P. & Andersen, Jesper Bøje, 11 Sep 2014, In: Journal of Hepatology.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. 2015
  48. Published

    Functional and genetic deconstruction of the cellular origin in liver cancer

    Marquardt, J. U., Andersen, Jesper Bøje & Thorgeirsson, S. S., 2015, In: Nature Reviews. Cancer. 15, 11, p. 653-67 15 p.

    Research output: Contribution to journal › Review › Research › peer-review

  49. Published

    Stimulating translational research: several European life science institutions put their heads together

    Bentires-Alj, M., Rajan, A., van Harten, W., van Luenen, H. G. A. M., Kubicek, S., Andersen, Jesper Bøje, Saarela, J., Cook, S. J., Van Minnebruggen, G., Roman-Roman, S., Maurer, C., Erler, Janine & Bertero, M. G., 2015, In: Trends in Molecular Medicine. 21, 9, p. 525-527 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Fibrolamellar Hepatocellular Carcinoma: A Rare But Distinct Type of Liver Cancer

    Andersen, Jesper Bøje, 24 Feb 2015, In: Gastroenterology.

    Research output: Contribution to journal › Editorial › Research › peer-review

  51. Published

    Curcumin effectively inhibits oncogenic NF-kB signaling and restrains stemness features in liver cancer

    Marquardt, J. U., Gomez-Quiroz, L., Arreguin Camacho, L. O., Pinna, F., Lee, Y., Kitade, M., Domínguez, M. P., Castven, D., Breuhahn, K., Conner, E. A., Galle, P. R., Andersen, Jesper Bøje, Factor, V. M. & Thorgeirsson, S. S., 30 Apr 2015, In: Journal of Hepatology.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Liver cancer oncogenomics: opportunities and dilemmas for clinical applications

    Marquardt, J. U. & Andersen, Jesper Bøje, 11 Aug 2015, In: Hepatic Oncology. 2, 1, p. 79-93 15 p.

    Research output: Contribution to journal › Review › Research › peer-review

  53. Published

    Transcriptional, post-transcriptional and chromatin-associated regulation of pri-miRNAs, pre-miRNAs and moRNAs

    Nepal, C., Coolen, M., Hadzhiev, Y., Cussigh, D., Mydel, P., Steen, V. M., Carninci, P., Andersen, Jesper Bøje, Bally-Cuif, L., Müller, F. & Lenhard, B., 15 Dec 2015, In: Nucleic Acids Research. 44, 11, p. 3070-3081 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. 2016

  55. A Gene Expression Signature Associated With Overall Survival in Patients With Hepatocellular Carcinoma Suggests a New Treatment Strategy

    Gillet, J., Andersen, Jesper Bøje, Madigan, J. P., Varma, S., Bagni, R. K., Powell, K., Burgan, W. E., Wu, C., Calcagno, A. M., Ambudkar, S. V., Thorgeirsson, S. S. & Gottesman, M., 2016, In: Molecular Pharmacology. 89, 2, p. 263-272 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    Molecular Pathogenesis and Current Therapy in Intrahepatic Cholangiocarcinoma

    Høgdall, Dan Taksony Solyom, O'Rourke, Colm, Taranta, A., NP Oliveira, D. & Andersen, Jesper Bøje, 2016, In: Digestive Diseases. 34, 4, p. 440-51 12 p.

    Research output: Contribution to journal › Review › Research › peer-review

  57. Published

    DNMT1 is a Required Genomic Regulator for Murine Liver Histogenesis and Regeneration

    Kaji, K., Factor, V. M., Andersen, Jesper Bøje, Durkin, M. E., Tomokuni, A., Marquardt, J. U., Matter, M. S., Hoang, T., Conner, E. A. & Thorgeirsson, S. S., 21 Mar 2016, In: Hepatology. 64, 2, p. 582–598 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    Heterogeneity Among Liver Cancer—A Hurdle to Optimizing Therapy

    Birkbak, N. J. & Andersen, Jesper Bøje, Apr 2016, In: Gastroenterology. 150, 4, p. 818–821 4 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  59. Published

    Cholangiocarcinoma: current knowledge and future perspectives consensus statement from the European Network for the Study of Cholangiocarcinoma (ENS-CCA)

    Banales, J. M., Cardinale, V., Carpino, G., Marzioni, M., Andersen, J. B., Invernizzi, P., Lind, G. E., Folseraas, T., Forbes, S. J., Fouassier, L., Geier, A., Calvisi, D. F., Mertens, J. C., Trauner, M., Benedetti, A., Maroni, L., Vaquero, J., Macias, R. I. R., Raggi, C., Perugorria, M. J. & 4 others, Gaudio, E., Boberg, K. M., Marin, J. J. G. & Alvaro, D., May 2016, In: Nature Reviews. Gastroenterology & Hepatology. 13, 5, p. 261-80 20 p.

    Research output: Contribution to journal › Review › Research › peer-review

  60. Published

    Expert consensus document: Cholangiocarcinoma: current knowledge and future perspectives consensus statement from the European Network for the Study of Cholangiocarcinoma (ENS-CCA)

    Banales, J. M., Cardinale, V., Carpino, G., Marzioni, M., Andersen, J. B., Invernizzi, P., Lind, G. E., Folseraas, T., Forbes, S. J., Fouassier, L., Geier, A., Calvisi, D. F., Mertens, J. C., Trauner, M., Benedetti, A., Maroni, L., Vaquero, J., Macias, R. I. R., Raggi, C., Perugorria, M. J. & 4 others, Gaudio, E., Boberg, K. M., Marin, J. J. G. & Alvaro, D., May 2016, In: Nature Reviews. Gastroenterology & Hepatology. 13, 5, p. 261-280 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    Oncogenic driver genes and the inflammatory microenvironment dictate liver tumor phenotype

    Matter, M. S., Marquardt, J. U., Andersen, Jesper Bøje, Quintavalle, C., Korokhov, N., Stauffer, J. K., Kaji, K., Decaens, T., Quagliata, L., Elloumi, F., Hoang, T., Molinolo, A., Conner, E. A., Weber, A., Heikenwalder, M., Factor, V. M. & Thorgeirsson, S. S., Jun 2016, In: Hepatology. 63, 6, p. 1888-1899 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    Correction:p53-Dependent Nestin Regulation Links Tumor Suppression to Cellular Plasticity in Liver Cancer

    Tschaharganeh, D. F., Xue, W., Calvisi, D. F., Evert, M., Michurina, T. V., Dow, L. E., Banito, A., Katz, S. F., Kastenhuber, E. R., Weissmueller, S., Huang, C., Lechel, A., Andersen, Jesper Bøje, Capper, D., Zender, L., Longerich, T., Enikolopov, G. & Lowe, S. W., 2 Jun 2016, In: Cell. 165, 6, p. 1546-1547 2 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

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ID: 93714085