Jesper Bøje Andersen
Professor
Andersen Group
Ole Maaløes Vej 5
2200 København N.
- 2004
Interaction between the 2'-5' oligoadenylate synthetase-like protein p59 OASL and the transcriptional repressor methyl CpG-binding protein 1
Andersen, Jesper Bøje, Strandbygård, D. J., Hartmann, R. & Justesen, J., Feb 2004, In: European Journal of Biochemistry. 271, 3, p. 628-36 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
Stage-associated overexpression of the ubiquitin-like protein, ISG15, in bladder cancer
Andersen, Jesper Bøje, Aaboe, M., Borden, E. C., Goloubeva, O. G., Hassel, B. A. & Orntoft, T. F., 22 May 2006, In: B J C. 94, 10, p. 1465-71 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
The interferon regulated ubiquitin-like protein, ISG15, in tumorigenesis: friend or foe?
Andersen, Jesper Bøje & Hassel, B. A., Dec 2006, In: Cytokine & Growth Factor Reviews. 17, 6, p. 411-21 11 p.Research output: Contribution to journal › Review › Research › peer-review
- 2007
Post-transcriptional regulation of RNase-L expression is mediated by the 3'-untranslated region of its mRNA
Li, X., Andersen, Jesper Bøje, Ezelle, H. J., Wilson, G. M. & Hassel, B. A., 16 Mar 2007, In: The Journal of Biological Chemistry. 282, 11, p. 7950-60 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Role of 2-5A-dependent RNase-L in senescence and longevity
Andersen, Jesper Bøje, Li, X. L., Judge, C. S., Zhou, A., Jha, B. K., Shelby, S., Zhou, L., Silverman, R. H. & Hassel, B. A., 10 May 2007, In: Oncogene. 26, 21, p. 3081-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
UBE1L causes lung cancer growth suppression by targeting cyclin D1
Feng, Q., Sekula, D., Guo, Y., Liu, X., Black, C. C., Galimberti, F., Shah, S. J., Sempere, L. F., Memoli, V., Andersen, Jesper Bøje, Hassel, B. A., Dragnev, K. & Dmitrovsky, E., Dec 2008, In: Molecular Cancer Therapeutics. 7, 12, p. 3780-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
Ribosomal protein mRNAs are primary targets of regulation in RNase-L-induced senescence
Andersen, Jesper Bøje, Mazan-Mamczarz, K., Zhan, M., Gorospe, M. & Hassel, B. A., 2009, In: RNA Biology. 6, 3, p. 305-15 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Loss of miR-122 expression in liver cancer correlates with suppression of the hepatic phenotype and gain of metastatic properties
Coulouarn, C., Factor, V. M., Andersen, Jesper Bøje, Durkin, M. E. & Thorgeirsson, S. S., 8 Oct 2009, In: Oncogene. 28, 40, p. 3526-36 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
Loss of c-Met disrupts gene expression program required for G2/M progression during liver regeneration in mice
Factor, V. M., Seo, D., Ishikawa, T., Kaposi-Novak, P., Marquardt, J. U., Andersen, Jesper Bøje, Conner, E. A. & Thorgeirsson, S. S., 2010, In: PLOS ONE. 5, 9Research output: Contribution to journal › Journal article › Research › peer-review
Progenitor-derived hepatocellular carcinoma model in the rat
Andersen, Jesper Bøje, Loi, R., Perra, A., Factor, V. M., Ledda-Columbano, G. M., Columbano, A. & Thorgeirsson, S. S., Apr 2010, In: Hepatology. 51, 4, p. 1401-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
An integrated genomic and epigenomic approach predicts therapeutic response to zebularine in human liver cancer
Andersen, Jesper Bøje, Factor, V. M., Marquardt, J. U., Raggi, C., Lee, Y., Seo, D., Conner, E. A. & Thorgeirsson, S. S., 20 Oct 2010, In: Science Translational Medicine. 2, 54, p. 54ra77Research output: Contribution to journal › Journal article › Research › peer-review
Definition of ubiquitination modulator COP1 as a novel therapeutic target in human hepatocellular carcinoma
Lee, Y., Andersen, Jesper Bøje, Song, H., Judge, A. D., Seo, D., Ishikawa, T., Marquardt, J. U., Kitade, M., Durkin, M. E., Raggi, C., Woo, H. G., Conner, E. A., Avital, I., Maclachlan, I., Factor, V. M. & Thorgeirsson, S. S., 1 Nov 2010, In: Cancer Research. 70, 21, p. 8264-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
Coactivation of AKT and β-catenin in mice rapidly induces formation of lipogenic liver tumors
Stauffer, J. K., Scarzello, A. J., Andersen, Jesper Bøje, De Kluyver, R. L., Back, T. C., Weiss, J. M., Thorgeirsson, S. S. & Wiltrout, R. H., 1 Apr 2011, In: Cancer Research. 71, 7, p. 2718-27 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Human hepatic cancer stem cells are characterized by common stemness traits and diverse oncogenic pathways
Marquardt, J. U., Raggi, C., Andersen, Jesper Bøje, Seo, D., Avital, I., Geller, D., Lee, Y., Kitade, M., Holczbauer, A., Gillen, M. C., Conner, E. A., Factor, V. M. & Thorgeirsson, S. S., 2 Sep 2011, In: Hepatology. 54, 3, p. 1031-42 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Notch signaling inhibits hepatocellular carcinoma following inactivation of the RB pathway
Viatour, P., Ehmer, U., Saddic, L. A., Dorrell, C., Andersen, Jesper Bøje, Lin, C., Zmoos, A., Mazur, P. K., Schaffer, B. E., Ostermeier, A., Vogel, H., Sylvester, K. G., Thorgeirsson, S. S., Grompe, M. & Sage, J., 26 Sep 2011, In: The Journal of Experimental Medicine. 208, 10, p. 1963-76 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
Molecular targeting of CSN5 in human hepatocellular carcinoma: a mechanism of therapeutic response
Lee, Y., Judge, A. D., Seo, D., Kitade, M., Gómez-Quiroz, L. E., Ishikawa, T., Andersen, Jesper Bøje, Kim, B., Marquardt, J. U., Raggi, C., Avital, I., Conner, E. A., MacLachlan, I., Factor, V. M. & Thorgeirsson, S. S., 6 Oct 2011, In: Oncogene. 30, 40, p. 4175-84 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
Genomic and genetic characterization of cholangiocarcinoma identifies therapeutic targets for tyrosine kinase inhibitors
Andersen, Jesper Bøje, Spee, B., Blechacz, B. R., Avital, I., Komuta, M., Barbour, A., Conner, E. A., Gillen, M. C., Roskams, T., Roberts, L. R., Factor, V. M. & Thorgeirsson, S. S., Apr 2012, In: Gastroenterology. 142, 4, p. 1021-1031.e15Research output: Contribution to journal › Journal article › Research › peer-review
Genetic profiling of intrahepatic cholangiocarcinoma
Andersen, Jesper Bøje & Thorgeirsson, S. S., May 2012, In: Current Opinion in Gastroenterology. 28, 3, p. 266-72 7 p.Research output: Contribution to journal › Review › Research › peer-review
mTOR inhibitors synergize on regression, reversal of gene expression, and autophagy in hepatocellular carcinoma
Thomas, H. E., Mercer, C. A., Carnevalli, L. S., Park, J., Andersen, Jesper Bøje, Conner, E. A., Tanaka, K., Matsutani, T., Iwanami, A., Aronow, B. J., Manway, L., Maira, S. M., Thorgeirsson, S. S., Mischel, P. S., Thomas, G. & Kozma, S. C., 20 Jun 2012, In: Science Translational Medicine. 4, 139, p. 139ra84Research output: Contribution to journal › Journal article › Research › peer-review
Next-Generation Sequencing: Application in Liver Cancer-Past, Present and Future?
Marquardt, J. U. & Andersen, Jesper Bøje, 31 Aug 2012, In: Biology. 1, 2, p. 383-394 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Transcriptomic profiling reveals hepatic stem-like gene signatures and interplay of miR-200c and epithelial-mesenchymal transition in intrahepatic cholangiocarcinoma
Oishi, N., Kumar, M. R., Roessler, S., Ji, J., Forgues, M., Budhu, A., Zhao, X., Andersen, Jesper Bøje, Ye, Q., Jia, H., Qin, L., Yamashita, T., Woo, H. G., Kim, Y. J., Kaneko, S., Tang, Z., Thorgeirsson, S. S. & Wang, X. W., Nov 2012, In: Hepatology. 56, 5, p. 1792-803 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
Molecular constituents of the extracellular matrix in rat liver mounting a hepatic progenitor cell response for tissue repair
Vestentoft, P. S., Jelnes, P., Andersen, Jesper Bøje, Tran, T. A. T., Jørgensen, T., Rasmussen, M., Lange, Jette Bornholdt, Grøvdal, L. M., Jensen, C. H., Vogel, Lotte, Thorgeirsson, S. S. & Bisgaard, Hanne Cathrine, 2013, In: Fibrogenesis & Tissue Repair. 6, 1, 15 p., 21.Research output: Contribution to journal › Journal article › Research › peer-review
Genomic decoding of intrahepatic cholangiocarcinoma reveals therapeutic opportunities
Andersen, Jesper Bøje & Thorgeirsson, S. S., Apr 2013, In: Gastroenterology. 144, 4, p. 687-90 4 p.Research output: Contribution to journal › Editorial › Research › peer-review
Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas
Wang, P., Dong, Q., Zhang, C., Kuan, P-F., Liu, Y., Jeck, W. R., Andersen, J. B., Jiang, W., Savich, G. L., Tan, T-X., Auman, J. T., Hoskins, J. M., Misher, A. D., Moser, C. D., Yourstone, S. M., Kim, J. W., Cibulskis, K., Getz, G., Hunt, H. V., Thorgeirsson, S. S. & 6 others, , 20 Jun 2013, In: Oncogene. 32, 25, p. 3091-100 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Modeling pathogenesis of primary liver cancer in lineage-specific mouse cell types
Holczbauer, A., Factor, V. M., Andersen, Jesper Bøje, Marquardt, J. U., Kleiner, D. E., Raggi, C., Kitade, M., Seo, D., Akita, H., Durkin, M. E. & Thorgeirsson, S. S., Jul 2013, In: Gastroenterology. 145, 1, p. 221-31 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Specific fate decisions in adult hepatic progenitor cells driven by MET and EGFR signaling
Kitade, M., Factor, V. M., Andersen, Jesper Bøje, Tomokuni, A., Kaji, K., Akita, H., Holczbauer, A., Seo, D., Marquardt, J. U., Conner, E. A., Lee, S., Lee, Y. & Thorgeirsson, S. S., 1 Aug 2013, In: Genes & Development. 27, 15, p. 1706-17 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Targeting the mTOR pathway in hepatocellular carcinoma: Current state and future trends
Matter, M. S., Decaens, T., Andersen, Jesper Bøje & Thorgeirsson, S. S., 3 Dec 2013, In: Journal of Hepatology.Research output: Contribution to journal › Review › Research › peer-review
- 2014
- Published
A perspective on molecular therapy in cholangiocarcinoma: present status and future directions
Andersen, Jesper Bøje & Thorgeirsson, S. S., 2014, In: Hepatic Oncology. 1, 1, p. 143-157 15 p.Research output: Contribution to journal › Review › Research › peer-review
Long noncoding RNA HOTTIP/HOXA13 expression is associated with disease progression and predicts outcome in hepatocellular carcinoma patients
Quagliata, L., Matter, M. S., Piscuoglio, S., Arabi, L., Ruiz, C., Procino, A., Kovac, M., Moretti, F., Makowska, Z., Boldanova, T., Andersen, Jesper Bøje, Hämmerle, M., Tornillo, L., Heim, M. H., Diederichs, S., Cillo, C. & Terracciano, L. M., 2014, In: Hepatology. 59, 3, p. 911-923Research output: Contribution to journal › Journal article › Research › peer-review
Epigenetic reprogramming modulates malignant properties of human liver cancer
Raggi, C., Factor, V. M., Seo, D., Holczbauer, A., Gillen, M. C., Marquardt, J. U., Andersen, Jesper Bøje, Durkin, M. & Thorgeirsson, S. S., 21 Jan 2014, In: Hepatology.Research output: Contribution to journal › Journal article › Research › peer-review
Sequential transcriptome analysis of human liver cancer indicates late stage acquisition of malignant traits
Marquardt, J. U., Seo, D., Andersen, Jesper Bøje, Gillen, M. C., Kim, M. S., Conner, E. A., Galle, P. R., Factor, V. M., Park, Y. N. & Thorgeirsson, S. S., Feb 2014, In: Journal of Hepatology. 60, 2, p. 346-53 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Antitumor effects in hepatocarcinoma of isoform-selective inhibition of HDAC2
Lee, Y., Seo, D., Choi, K., Andersen, Jesper Bøje, Won, M., Kitade, M., Gomez-Quiroz, L. E., Judge, A. D., Marquardt, J. U., Raggi, C., Conner, E. A., MacLachlan, I., Factor, V. M. & Thorgeirsson, S., 23 Jun 2014, In: Cancer Research. 74, 17, p. 4752-4761 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
p53-Dependent Nestin Regulation Links Tumor Suppression to Cellular Plasticity in Liver Cancer
Tschaharganeh, D. F., Xue, W., Calvisi, D. F., Evert, M., Michurina, T. V., Dow, L. E., Banito, A., Katz, S. F., Kastenhuber, E. R., Weissmueller, S., Huang, C., Lechel, A., Andersen, Jesper Bøje, Capper, D., Zender, L., Longerich, T., Enikolopov, G. & Lowe, S. W., 31 Jul 2014, In: Cell. 158, 3, p. 579-92 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular pathogenesis of intrahepatic cholangiocarcinoma
Andersen, Jesper Bøje, 1 Sep 2014, In: Journal of Hepato - Biliary - Pancreatic Sciences.Research output: Contribution to journal › Review › Research › peer-review
- Published
MYC activates stem-like cell potential in hepatocarcinoma by a p53-dependent mechanism
Akita, H., Marquardt, J. U., Durkin, M. E., Kitade, M., Seo, D., Conner, E. A., Andersen, Jesper Bøje, Factor, V. M. & Thorgeirsson, S. S., 4 Sep 2014, In: Cancer Research.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of Microenvironment and Stem-Like Plasticity in Cholangiocarcinoma: Molecular Networks and Biological Concepts
Raggi, C., Invernizzi, P. & Andersen, Jesper Bøje, 11 Sep 2014, In: Journal of Hepatology.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Functional and genetic deconstruction of the cellular origin in liver cancer
Marquardt, J. U., Andersen, Jesper Bøje & Thorgeirsson, S. S., 2015, In: Nature Reviews. Cancer. 15, 11, p. 653-67 15 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Stimulating translational research: several European life science institutions put their heads together
Bentires-Alj, M., Rajan, A., van Harten, W., van Luenen, H. G. A. M., Kubicek, S., Andersen, Jesper Bøje, Saarela, J., Cook, S. J., Van Minnebruggen, G., Roman-Roman, S., Maurer, C., Erler, Janine & Bertero, M. G., 2015, In: Trends in Molecular Medicine. 21, 9, p. 525-527 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fibrolamellar Hepatocellular Carcinoma: A Rare But Distinct Type of Liver Cancer
Andersen, Jesper Bøje, 24 Feb 2015, In: Gastroenterology.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Curcumin effectively inhibits oncogenic NF-kB signaling and restrains stemness features in liver cancer
Marquardt, J. U., Gomez-Quiroz, L., Arreguin Camacho, L. O., Pinna, F., Lee, Y., Kitade, M., Domínguez, M. P., Castven, D., Breuhahn, K., Conner, E. A., Galle, P. R., Andersen, Jesper Bøje, Factor, V. M. & Thorgeirsson, S. S., 30 Apr 2015, In: Journal of Hepatology.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Liver cancer oncogenomics: opportunities and dilemmas for clinical applications
Marquardt, J. U. & Andersen, Jesper Bøje, 11 Aug 2015, In: Hepatic Oncology. 2, 1, p. 79-93 15 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Transcriptional, post-transcriptional and chromatin-associated regulation of pri-miRNAs, pre-miRNAs and moRNAs
Nepal, C., Coolen, M., Hadzhiev, Y., Cussigh, D., Mydel, P., Steen, V. M., Carninci, P., Andersen, Jesper Bøje, Bally-Cuif, L., Müller, F. & Lenhard, B., 15 Dec 2015, In: Nucleic Acids Research. 44, 11, p. 3070-3081 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
A Gene Expression Signature Associated With Overall Survival in Patients With Hepatocellular Carcinoma Suggests a New Treatment Strategy
Gillet, J., Andersen, Jesper Bøje, Madigan, J. P., Varma, S., Bagni, R. K., Powell, K., Burgan, W. E., Wu, C., Calcagno, A. M., Ambudkar, S. V., Thorgeirsson, S. S. & Gottesman, M., 2016, In: Molecular Pharmacology. 89, 2, p. 263-272 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular Pathogenesis and Current Therapy in Intrahepatic Cholangiocarcinoma
Høgdall, Dan Taksony Solyom, O'Rourke, Colm, Taranta, A., NP Oliveira, D. & Andersen, Jesper Bøje, 2016, In: Digestive Diseases. 34, 4, p. 440-51 12 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
DNMT1 is a Required Genomic Regulator for Murine Liver Histogenesis and Regeneration
Kaji, K., Factor, V. M., Andersen, Jesper Bøje, Durkin, M. E., Tomokuni, A., Marquardt, J. U., Matter, M. S., Hoang, T., Conner, E. A. & Thorgeirsson, S. S., 21 Mar 2016, In: Hepatology. 64, 2, p. 582–598 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Heterogeneity Among Liver Cancer—A Hurdle to Optimizing Therapy
Birkbak, N. J. & Andersen, Jesper Bøje, Apr 2016, In: Gastroenterology. 150, 4, p. 818–821 4 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Cholangiocarcinoma: current knowledge and future perspectives consensus statement from the European Network for the Study of Cholangiocarcinoma (ENS-CCA)
Banales, J. M., Cardinale, V., Carpino, G., Marzioni, M., Andersen, J. B., Invernizzi, P., Lind, G. E., Folseraas, T., Forbes, S. J., Fouassier, L., Geier, A., Calvisi, D. F., Mertens, J. C., Trauner, M., Benedetti, A., Maroni, L., Vaquero, J., Macias, R. I. R., Raggi, C., Perugorria, M. J. & 4 others, , May 2016, In: Nature Reviews. Gastroenterology & Hepatology. 13, 5, p. 261-80 20 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Expert consensus document: Cholangiocarcinoma: current knowledge and future perspectives consensus statement from the European Network for the Study of Cholangiocarcinoma (ENS-CCA)
Banales, J. M., Cardinale, V., Carpino, G., Marzioni, M., Andersen, J. B., Invernizzi, P., Lind, G. E., Folseraas, T., Forbes, S. J., Fouassier, L., Geier, A., Calvisi, D. F., Mertens, J. C., Trauner, M., Benedetti, A., Maroni, L., Vaquero, J., Macias, R. I. R., Raggi, C., Perugorria, M. J. & 4 others, , May 2016, In: Nature Reviews. Gastroenterology & Hepatology. 13, 5, p. 261-280 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oncogenic driver genes and the inflammatory microenvironment dictate liver tumor phenotype
Matter, M. S., Marquardt, J. U., Andersen, Jesper Bøje, Quintavalle, C., Korokhov, N., Stauffer, J. K., Kaji, K., Decaens, T., Quagliata, L., Elloumi, F., Hoang, T., Molinolo, A., Conner, E. A., Weber, A., Heikenwalder, M., Factor, V. M. & Thorgeirsson, S. S., Jun 2016, In: Hepatology. 63, 6, p. 1888-1899 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Correction:p53-Dependent Nestin Regulation Links Tumor Suppression to Cellular Plasticity in Liver Cancer
Tschaharganeh, D. F., Xue, W., Calvisi, D. F., Evert, M., Michurina, T. V., Dow, L. E., Banito, A., Katz, S. F., Kastenhuber, E. R., Weissmueller, S., Huang, C., Lechel, A., Andersen, Jesper Bøje, Capper, D., Zender, L., Longerich, T., Enikolopov, G. & Lowe, S. W., 2 Jun 2016, In: Cell. 165, 6, p. 1546-1547 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
ID: 93714085
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Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles - correction
Research output: Contribution to journal › Comment/debate › Research › peer-review
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A Pan-Cancer Analysis Reveals High-Frequency Genetic Alterations in Mediators of Signaling by the TGF-β Superfamily
Research output: Contribution to journal › Journal article › Research › peer-review
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MIR21 drives resistance to Heat Shock Protein 90 inhibition in cholangiocarcinoma
Research output: Contribution to journal › Journal article › Research › peer-review
Published