Lund Group

The aim of the laboratory is to unveil fundamental biological mechanisms and understand how these become perturbed during diseases, most prominently cancer, with the ambition that our findings may contribute to the development of clinical tools.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

  • Translational control through ribosome heterogeneity and functional specialization.
  • Regulation of translation by site-specific ribosomal RNA methylation.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Selected publications

Translational control through ribosome heterogeneity and functional specialization. David M. Gay, Anders H. Lund, Martin D. Jansson.(2021).

    The lncRNA MIR31HG regulates the senescence associated secretory phenotype. Montes, M., Lubas, M., Arendrup, F.S., Mentz, B., Rohatgi, N., Tumas, S., Harder, L.M., Skanderup, A.J., Andersen, J.S., and A.H. Lund. (2021).

    Regulation of translation by site-specific ribosomal RNA methylation. Jansson, M.D., Häfner, S.J., Altinel, K., Tehler, D.E., Krogh, N., Jacobsen, E., Andersen, J.V., Andersen, K.L., Ménard, P., Nielsen, H., and A.H. Lund. (2020). Preprint.

    Repeat RNAs associate with replication forks and post-replicative DNA. Gylling, H.M., Gonzalez-Aguilera, C., Smith, M.A., Kaczorowski, D.C., Groth, A., and A.H. Lund. (2020). RNA. doi:

    10.1261/rna.074757.120.

    A high-throughput screen identifies the long noncoding RNA DRAIC as a regulator of autophagy.

    Tiessen, I., Abildgaard, M.H., Lubas, M., Gylling, H.M. Steinhauer, C., Pietras, E.J., Diederichs, S., Frankel, L.B*. and A.H. Lund* (2019). Oncogene, doi: 10.1038/s41388-019-0783-9.

    Eukaryotic translation initiation factor 5A mediates translational control of autophagy via ATG3. Lubas, M., Harder, L.M., Kumsta, C., Tiessen, I., Hansen, M., Andersen, J.S., Lund, A.H.* and Frankel, L.B.* (2018). (*Co-corresponding authors). EMBO Reports, doi: 10.15252/embr.201846072.

    Emerging connections between RNA and autophagy. Frankel, L.B., Lubas, M. and A.H. Lund (2016).. Autophagy. doi:10.1080/15548627.2016.1222992.

    All publications 

     

     

     

     

     

     

     

     

     

     

     

     

     

    Molecular hijacking: Cancer gene re-programs ‘protein factories’ to stimulate cell growth

    23.11.2021

    The ribosomes, the ‘protein factories’ in our cells, can be altered by cancer genes, a new study from the University of Copenhagen shows.

    PUBLICATION SPOTLIGHT - The long non-coding RNA MIR31HG regulates the senescence associated secretory phenotype

    27.04.2021

    By Marta Montes Resano, Assistant professor, Lund Group.

    Distinguished Investigator Grant for Anders H. Lund


    04.04.2018

    Professor and group leader Anders H. Lund has received a Distinguished Investigator grant of DKK 10 

    Overraskelser i arvemassen


    27.02.2016

    Article published in Weekendavisen (in Danish) on the importance of junk DNA. 

    2 BRIC researchers awarded Sapere Aude grants


    23.06.2015

    Group Leader, Professor Anders H. Lund and Group Leader, Associate Professor Jesper B. Andersen have  

    Nyt molekyle spiller vigtig rolle i forståelsen af kræft

    09.04.2015

    Article published on Videnskab.dk (in Danish) which unveils the function of a novel molecule,