Michael Ploug
Group leader
Ploug Group
Ole Maaløes Vej 5
2200 København N.
- 2024
- Published
CL-11 circulates in serum as functionally distinct isoforms
Sutta, A., Leemans, N. N., Ploug, Michael, Rosbjerg, A., del Agua Villa, C., Pérez-Alós, L., Cyranka, L., Vincek, A. S., de Garay, T., Rivera, K. & Bayarri-Olmos, R., 2024, In: FASEB Journal. 38, 5, e23543.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantification of lipoprotein lipase in mouse plasma with a sandwich enzyme-linked immunosorbent assay
Kimura, T., Miyashita, K., Fukamachi, I., Fukamachi, K., Ogura, K., Yokoyama, E., Tsunekawa, K., Nagasawa, T., Ploug, Michael, Yang, Y., Song, W., Young, S. G., Beigneux, A. P., Nakajima, K. & Murakami, M., 2024, In: Journal of Lipid Research. 65, 4, 7 p., 100532.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
Hypertriglyceridemia in Apoa5-/- mice results from reduced amounts of lipoprotein lipase in the capillary lumen
Yang, Y., Beigneux, A. P., Song, W., Nguyen, L. P., Jung, H., Tu, Y., Weston, T. A., Tran, C. M., Xie, K., Yu, R. G., Tran, A. P., Miyashita, K., Nakajima, K., Murakami, M., Chen, Y. Q., Zhen, E. Y., Kim, J. R., Kim, P. H., Birrane, G., Tontonoz, P. & 4 others, , 2023, In: Journal of Clinical Investigation. 133, 23, 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intracapillary LPL levels in brown adipose tissue, visualized with an antibody-based approach, are regulated by ANGPTL4 at thermoneutral temperatures
Song, W., Yang, Y., Heizer, P., Tu, Y., Weston, T. A., Kim, J. R., Munguia, P., Jung, H., Fong, J. L. C., Tran, C., Ploug, Michael, Beigneux, A. P., Young, S. G. & Fong, L. G., 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 8, 11 p., e2219833120.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inverse effects of APOC2 and ANGPTL4 on the conformational dynamics of lid-anchoring structures in lipoprotein lipase
Kumari, Anni, Grønnemose, A. L., Kristensen, Kristian Kølby, Winther, Anne-Marie Lund, Young, S. G., Jørgensen, T. J. D. & Ploug, Michael, 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 18, e2221888120.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Targeted imaging of uPAR expression in vivo with cyclic AE105 variants
Leth, Julie Maja, Newcombe, Estella Anne, Grønnemose, A. L., Jørgensen, Jesper Tranekjær, Qvist, K., Clausen, Anne Skovsbo, Knudsen, Line Bruhn Schneider, Kjær, Andreas, Kragelund, Birthe Brandt, Jørgensen, Thomas Jørgen Dyreborg & Ploug, Michael, 2023, In: Scientific Reports. 13, 17 p., 17248.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The lipoprotein lipase that is shuttled into capillaries by GPIHBP1 enters the glycocalyx where it mediates lipoprotein processing
Song, W., Beigneux, A. P., Weston, T. A., Chen, K., Yang, Y., Nguyen, L. P., Guagliardo, P., Jung, H., Tran, A. P., Tu, Y., Tran, C., Birrane, G., Miyashita, K., Nakajima, K., Murakami, M., Tontonoz, P., Jiang, H., Ploug, Michael, Fong, L. G. & Young, S. G., 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 44, 12 p., e2313825120.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
A protein of capillary endothelial cells, GPIHBP1, is crucial for plasma triglyceride metabolism
Young, S. G., Song, W., Yang, Y., Birrane, G., Jiang, H., Beigneux, A. P., Ploug, Michael & Fong, L. G., 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 36, 12 p., e2211136119.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ANGPTL4: a new mode in the regulation of intravascular lipolysis
Ploug, Michael, 2022, In: Current Opinion in Lipidology. 33, 2, p. 112-119Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Electrostatic sheathing of lipoprotein lipase is essential for its movement across capillary endothelial cells
Song, W., Beigneux, A. P., Winther, A. M. L., Kristensen, K. K., Grønnemose, A. L., Yang, Y., Tu, Y., Munguia, P., Morales, J., Jung, H., De Jong, P. J., Jung, C. J., Miyashita, K., Kimura, T., Nakajima, K., Murakami, M., Birrane, G., Jiang, H., Tontonoz, P., Ploug, M. & 2 others, , 2022, In: Journal of Clinical Investigation. 132, 5, 15 p., e157500.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
ANGPTL4 sensitizes lipoprotein lipase to PCSK3 cleavage by catalyzing its unfolding
Winther, Anne-Marie Lund, Kumari, Anni, Young, S. G. & Ploug, Michael, 2021, In: Journal of Lipid Research. 62, 2 p., 100071.Research output: Contribution to journal › Comment/debate › Research
- Published
Disorder in a two-domain neuronal Ca2+-binding protein regulates domain stability and dynamics using ligand mimicry
Staby, L., Kemplen, K. R., Stein, Amelie, Ploug, Michael, Clarke, J., Skriver, Karen, Heidarsson, P. O. & Kragelund, Birthe Brandt, 2021, In: Cellular and molecular life sciences : CMLS. 78, p. 2263-2278 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expression and one-step purification of active LPL contemplated by biophysical considerations
Winther, Anne-Marie Lund, Kristensen, Kristian Kølby, Kumari, Anni & Ploug, Michael, 2021, In: Journal of Lipid Research. 62, 13 p., 100149.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GPIHBP1 and ANGPTL4 Utilize Protein Disorder to Orchestrate Order in Plasma Triglyceride Metabolism and Regulate Compartmentalization of LPL Activity
Kristensen, Kristian Kølby, Leth-Espensen, K. Z., Kumari, Anni, Grønnemose, A. L., Winther, Anne-Marie Lund, Young, S. G. & Ploug, Michael, 2021, In: Frontiers in Cell and Developmental Biology. 9, 20 p., 702508.Research output: Contribution to journal › Review › Research › peer-review
- Published
IRDye800CW labeled uPAR-targeting peptide for fluorescence-guided glioblastoma surgery: Preclinical studies in orthotopic xenografts
Kurbegovic, Sorel, Stræde, Karina, Sørensen, K. K., Leth, Julie Maja, Willemoe, G. L., Christensen, Anders, Adams, Yvonne, Jensen, Anja Ramstedt, von Buchwald, Christian, Skjøth-rasmussen, J., Ploug, Michael, Jensen, Knud Jørgen & Kjær, Andreas, 2021, In: Theranostics. 11, 15, p. 7159-7174 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Optimization and Evaluation of Al18F Labeling Using a NOTA—or RESCA1-Conjugated AE105 Peptide Antagonist of uPAR
Jeppesen, T. E., Simón, M., Torp, J., Knudsen, Line Bruhn Schneider, Leth, Julie Maja, Crestey, F., Ploug, Michael, Jørgensen, Jesper Tranekjær, Madsen, J., Herth, Matthias Manfred & Kjær, Andreas, 2021, In: Frontiers in Nuclear Medicine. 1, 9 p., 799533.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Targeting the Urokinase-Type Plasminogen Activator Receptor (uPAR) in Human Diseases With a View to Non-invasive Imaging and Therapeutic Intervention
Leth, Julie Maja & Ploug, Michael, 2021, In: Frontiers in Cell and Developmental Biology. 9, 20 p., 732015.Research output: Contribution to journal › Review › Research › peer-review
- Published
The Importance of Lipoprotein Lipase Regulation in Atherosclerosis
Kumari, Anni, Kristensen, Kristian Kølby, Ploug, Michael & Winther, Anne-Marie Lund, 2021, In: Biomedicines. 9, 7, 24 p., 782.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Urokinase Receptor (uPAR) as a “Trojan Horse” in Targeted Cancer Therapy: Challenges and Opportunities
Metrangolo, Virginia, Ploug, Michael & Engelholm, Lars Henning, 2021, In: Cancers. 13, 21, 45 p., 5376.Research output: Contribution to journal › Review › Research › peer-review
- Published
The intrinsic instability of the hydrolase domain of lipoprotein lipase facilitates its inactivation by ANGPTL4-catalyzed unfolding
Leth-Espensen, K. Z., Kristensen, Kristian Kølby, Kumari, Anni, Winther, Anne-Marie Lund, Young, S. G., Jørgensen, T. J. D. & Ploug, Michael, 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 12, e2026650118.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
ANGPTL4 inactivates lipoprotein lipase by catalyzing the irreversible unfolding of LPL's hydrolase domain
Kristensen, Kristian Kølby, Leth-Espensen, K. Z., Young, S. G. & Ploug, Michael, 2020, In: Journal of Lipid Research. 61, 9, p. 1253Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chylomicronemia From GPIHBP1 Autoantibodies Successfully Treated With Rituximab: A Case Report
Lutz, J., Dunaj-Kazmierowska, M., Arcan, S., Kassner, U., Miyashita, K., Murakami, M., Ploug, Michael, Fong, L. G., Young, S. G., Nakajima, K. & Beigneux, A. P., 2020, In: Annals of Internal Medicine. 173, 9, p. 764-765Research output: Contribution to journal › Letter › Research › peer-review
- Published
Chylomicronemia from GPIHBP1 autoantibodies
Miyashita, K., Lutz, J., Hudgins, L. C., Toib, D., Ashraf, A. P., Song, W., Murakami, M., Nakajima, K., Ploug, Michael, Fong, L. G., Young, S. G. & Beigneux, A. P., 2020, In: Journal of Lipid Research. 61, 11, p. 1365-1376Research output: Contribution to journal › Review › Research › peer-review
- Published
Crystal Structures of Human C4.4A Reveal the Unique Association of Ly6/uPAR/α-neurotoxin Domain
Jiang, Y., Lin, L., Chen, S., Jiang, L., Kriegbaum, M. C., Gårdsvoll, Henrik, Hansen, L. V., Li, J., Ploug, Michael, Yuan, C. & Huang, M., 2020, In: International Journal of Biological Sciences. 16, 6, p. 981-993 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Determination of Binding Kinetics of Intrinsically Disordered Proteins by Surface Plasmon Resonance
Leth, Julie Maja & Ploug, Michael, 2020, Intrinsically Disorded Proteins. Kragelund, B. & Skriver, K. (eds.). Springer, Vol. 2141. p. 611-627 17 p. (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Efficient refolding and reconstitution of tissue factor into nanodiscs facilitates structural investigation of a multicomponent system on a lipid bilayer
Tidemand, Frederik Grønbæk, Østergaard, H., Ploug, Michael, Kragelund, Birthe Brandt & Arleth, Lise, 2020, In: Biochimica et Biophysica Acta - Biomembranes. 1862, 6, 10 p., 183214.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Helicobacter pylori Colonization Drives Urokinase Receptor (uPAR) Expression in Murine Gastric Epithelium During Early Pathogenesis
Alpízar-Alpízar, W., Skindersoe, M. E., Rasmussen, L., Kriegbaum, M. C., Christensen, I. J., Lund, I. K., Illemann, M., Laerum, O. D., Krogfelt, K. A., Andersen, L. P. & Ploug, Michael, 2020, In: Microorganisms. 8, 7, 1019.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intermittent chylomicronemia caused by intermittent GPIHBP1 autoantibodies
Ashraf, A. P., Miyashita, K., Nakajima, K., Murakami, M., Hegele, R. A., Ploug, Michael, Fong, L. G., Young, S. G. & Beigneux, A. P., 2020, In: Journal of Clinical Lipidology. 14, 2, p. 197-200Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Small-Molecule Inhibition of the uPAR uPA Interaction by Conformational Selection
Xu, D., Bum-Erdene, K., Leth, Julie Maja, Ghozayel, M. K., Ploug, Michael & Meroueh, S. O., 2020, In: ChemMedChem. 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The structural basis for monoclonal antibody 5D2 binding to the tryptophan-rich loop of lipoprotein lipase
Luz, J., Beigneux, A. P., Asamoto, D. K., He, C., Song, W., Allan, C. M., Morales, J. E., Tu, Y., Kwok, A., Cottle, T., Meiyappan, M., Fong, L. G., Kim, J., Ploug, Michael, Young, S. G. & Birrane, G., 2020, In: Journal of Lipid Research. 61, 10, p. 1347-1359Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Unfolding of monomeric lipoprotein lipase by ANGPTL4: Insight into the regulation of plasma triglyceride metabolism
Kristensen, Kristian Kølby, Leth-Espensen, K. Z., Mertens, H. D. T., Birrane, G., Meiyappan, M., Olivecrona, G., Jørgensen, T. J. D., Young, S. G. & Ploug, Michael, 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 8, p. 4337-4346Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Crystal structure of the unoccupied murine urokinase-type plasminogen activator receptor (uPAR) reveals a tightly packed DII-DIII unit
Liu, M., Hansen, G. H., Ploug, Michael, Hanlin, L., Jiang, L., Yuan, C., Li, J. & Huang, M., 2019, In: FEBS Letters. 593, 11, p. 1236-1247 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Did evolution create a flexible ligand-binding cavity in the urokinase receptor through deletion of a plesiotypic disulfide bond?
Leth, Julie Maja, Mertens, H. D. T., Leth-Espensen, K. Z., Jørgensen, T. J. D. & Ploug, Michael, 2019, In: The Journal of Biological Chemistry. 294, 18, p. 7403-7418 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evolution and Medical Significance of LU Domain-Containing Proteins
Leth, Julie Maja, Leth-Espensen, K. Z., Kristensen, Kristian Kølby, Kumari, Anni, Winther, Anne-Marie Lund, Young, S. G. & Ploug, Michael, 2019, In: International Journal of Molecular Sciences. 20, 11, p. 1-20 20 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
GPIHBP1 and Lipoprotein Lipase, Partners in Plasma Triglyceride Metabolism
Young, S. G., Fong, L. G., Beigneux, A. P., Allan, C. M., He, C., Jiang, H., Nakajima, K., Meiyappan, M., Birrane, G. & Ploug, Michael, 2019, In: Cell Metabolism. 30, 1, p. 51-65 15 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
GPIHBP1 autoantibody syndrome during interferon β1a treatment
Eguchi, J., Miyashita, K., Fukamachi, I., Nakajima, K., Murakami, M., Kawahara, Y., Yamashita, T., Ohta, Y., Abe, K., Nakatsuka, A., Mino, M., Takase, S., Okazaki, H., Hegele, R. A., Ploug, Michael, Hu, X., Wada, J., Young, S. G. & Beigneux, A. P., 2019, In: Journal of Clinical Lipidology. 13, 1, p. 62-69 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lipoprotein lipase is active as a monomer
Beigneux, A. P., Allan, C. M., Sandoval, N. P., Cho, G. W., Heizer, P. J., Jung, R. S., Stanhope, K. L., Havel, P. J., Birrane, G., Meiyappan, M., Gill, J. E., Murakami, M., Miyashita, K., Nakajima, K., Ploug, Michael, Fong, L. G. & Young, S. G., 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 13, p. 6319-6328 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
On the mechanism of angiopoietin-like protein 8 for control of lipoprotein lipase activity
Kovrov, O., Kristensen, Kristian Kølby, Larsson, E., Ploug, Michael & Olivecrona, G., 2019, In: Journal of Lipid Research. 60, 4, p. 783-793 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Origin and diversification of the plasminogen activation system among chordates
Chana-Muñoz, A., Jendroszek, A., Sønnichsen, M., Wang, T., Ploug, Michael, Jensen, J. K., Andreasen, P. A., Bendixen, C. & Panitz, F., 2019, In: BMC Evolutionary Biology. 19, 1, p. 1-17 17 p., 27.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Peptide disc mediated control of membrane protein orientation in supported lipid bilayers for surface-sensitive investigations
Luchini, A., Tidemand, Frederik Grønbæk, Johansen, Nicolai Tidemand, Campana, M., Sotres, J., Ploug, Michael, Cárdenas, M. & Arleth, Lise, 2019, In: Analytical Chemistry. 92, 1, p. 1081-1088Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure of the lipoprotein lipase-GPIHBP1 complex that mediates plasma triglyceride hydrolysis
Birrane, G., Beigneux, A. P., Dwyer, B., Strack-Logue, B., Kristensen, Kristian Kølby, Francone, O. L., Fong, L. G., Mertens, H. D. T., Pan, C. Q., Ploug, Michael, Young, S. G. & Meiyappan, M., 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 5, p. 1723-1732 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The PCNA interaction motifs revisited: thinking outside the PIP-box
Prestel, Andreas, Wichmann, N., Martins, J. M., Marabini, R., Kassem, N., Broendum, S. S., Otterlei, M., Nielsen, Olaf, Willemoës, Martin, Ploug, Michael, Boomsma, Wouter & Kragelund, Birthe Brandt, 2019, In: Cellular and Molecular Life Sciences. 76, 24, p. 4923-4943Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
NanoSIMS Analysis of Intravascular Lipolysis and Lipid Movement across Capillaries and into Cardiomyocytes
He, C., Weston, T. A., Jung, R. S., Heizer, P., Larsson, M., Hu, X., Allan, C. M., Tontonoz, P., Reue, K., Beigneux, A. P., Ploug, Michael, Holme, A., Kilburn, M., Guagliardo, P., Ford, D. A., Fong, L. G., Young, S. G. & Jiang, H., 1 May 2018, In: Cell Metabolism. 27, 5, p. 1055-1066.e3 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An enzyme-linked immunosorbent assay for measuring GPIHBP1 levels in human plasma or serum
Miyashita, K., Fukamachi, I., Nagao, M., Ishida, T., Kobayashi, J., Machida, T., Nakajima, K., Murakami, M., Ploug, Michael, Beigneux, A. P., Young, S. G. & Nakajima, K., Jan 2018, In: Journal of Clinical Lipidology. 12, 1, p. 203-210 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A disordered acidic domain in GPIHBP1 harboring a sulfated tyrosine regulates lipoprotein lipase
Kristensen, Kristian Kølby, Midtgaard, S. R., Mysling, S., Kovrov, O., Hansen, L. B., Skar-Gislinge, Nicholas, Beigneux, A. P., Kragelund, Birthe Brandt, Olivecrona, G., Young, S. G., Jørgensen, T. J. D., Fong, L. G. & Ploug, Michael, 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 26, p. E6020-E6029 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Expression and crystallographic studies of the D1D2 domains of C4.4A, a homologous protein to the urokinase receptor
Chen, S., Lin, L., Yuan, C., Gårdsvoll, Henrik, Kriegbaum, M. C., Ploug, Michael & Huang, M., 1 Aug 2017, In: Acta Crystallographica Section F: Structural Biology Communications. 73, 8, p. 486-490 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GPIHBP1 autoantibodies in a patient with unexplained chylomicronemia
Hu, X., Dallinga-Thie, G. M., Hovingh, G. K., Chang, S. Y., Sandoval, N. P., Dang, T. L. P., Fukamachi, I., Miyashita, K., Nakajima, K., Murakami, M., Fong, L. G., Ploug, Michael, Young, S. G. & Beigneux, A. P., 1 Jul 2017, In: Journal of Clinical Lipidology. 11, 4, p. 964-971 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Autoantibodies against GPIHBP1 as a Cause of Hypertriglyceridemia
Beigneux, A. P., Miyashita, K., Ploug, M., Blom, J. D., Ai, M., Linton, M. F., Khovidhunkit, W., Dufour, R., Garg, A., McMahon, M. A., Pullinger, C. R., Sandoval, N. P., Hu, X., Allan, C. M., Larsson, M., Machida, T., Murakami, M., Reue, K., Tontonoz, P., Goldberg, I. J. & 5 others, , 27 Apr 2017, In: New England Journal of Medicine. 376, 17, p. 1647-1658 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mobility of “HSPG-bound” LPL explains how LPL is able to reach GPIHBP1 on capillaries
Allan, C. M., Larsson, M., Jung, R. S., Ploug, Michael, Bensadoun, A., Beigneux, A. P., Fong, L. G. & Young, S. G., Jan 2017, In: Journal of Lipid Research. 58, 1, p. 216-225Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Monoclonal Antibodies That Bind to the Ly6 Domain of GPIHBP1 Abolish the Binding of LPL
Hu, X., Sleeman, M. W., Miyashita, K., Linton, M. F., Allan, C. M., He, C., Larsson, M., Tu, Y., Sandoval, N. P., Jung, R. S., Mapar, A., Machida, T., Murakami, M., Nakajima, K., Ploug, Michael, Fong, L. G., Young, S. G. & Beigneux, A. P., Jan 2017, In: Journal of Lipid Research. 58, p. 208-215 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expression of C4.4A in an in Vitro Human Tissue-Engineered Skin Model
Jacobsen, B., Larouche, D., Rochette-Drouin, O., Ploug, Michael & Germain, L., 2017, In: BioMed Research International. 2017, 9 p., 2403072.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
The angiopoietin-like protein ANGPTL4 catalyzes unfolding of the hydrolase domain in lipoprotein lipase and the endothelial membrane protein GPIHBP1 counteracts this unfolding
Mysling, S., Kristensen, K. K., Larsson, M., Kovrov, O., Bensadouen, A., Jørgensen, T. J. D., Olivecrona, G., Young, S. G. & Ploug, Michael, 8 Dec 2016, In: eLife. 5, 18 p., e20958.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A lipoprotein lipase (LPL)-specific monoclonal antibody, 88B8, that abolishes the binding of LPL to GPIHBP1
Allan, C. M., Larsson, M., Hu, X., He, C., Jung, R. S., Mapar, A., Voss, C., Miyashita, K., Machida, T., Murakami, M., Nakajima, K., Bensadoun, A., Ploug, Michael, Fong, L. G., Young, S. G. & Beigneux, A. P., Oct 2016, In: Journal of Lipid Research. 57, 10, p. 1889-1898Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tissue Inhibitor of Metalloproteinase-1 Is Confined to Tumor-Associated Myofibroblasts and Is Increased With Progression in Gastric Adenocarcinoma
Alpízar-Alpízar, W., Lærum, O. D., Christensen, I. J., Ovrebo, K., Skarstein, A., Høyer-Hansen, G., Ploug, Michael & Illemann, M., Aug 2016, In: Journal of Histochemistry and Cytochemistry. 64, 8, p. 483-94 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GPIHBP1 and Plasma Triglyceride Metabolism
Fong, L. G., Young, S. G., Beigneux, A. P., Bensadoun, A., Oberer, M., Jiang, H. & Ploug, Michael, Jul 2016, In: Trends in Endocrinology and Metabolism. 27, 7, p. 455-69 15 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
C4.4A gene ablation is compatible with normal epidermal development and causes modest overt phenotypes
Kriegbaum, M. C., Jacobsen, B., Fuchtbauer, A., Hansen, Gert Helge, Christensen, I. J., Friis, Carsten, Persson, M., Engelholm, Lars Henning, Madsen, A. N., Di Meo, I., Lund, I. K., Holst, Birgitte, Kjær, Andreas, Laerum, O. D., Fuchtbauer, E. & Ploug, Michael, 12 May 2016, In: Scientific Reports. 6, 25833.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Peptide-Based Optical uPAR Imaging for Surgery: In Vivo Testing of ICG-Glu-Glu-AE105
Stræde, Karina, Christensen, Anders, Persson, M., Ploug, Michael & Kjær, Andreas, 2016, In: PloS one. 11, 2, 15 p., e0147428.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The acidic domain of the endothelial membrane protein GPIHBP1 stabilizes lipoprotein lipase activity by preventing unfolding of its catalytic domain
Mysling, S., Kristensen, K. K., Larsson, M., Beigneux, A. P., Gårdsvoll, Henrik, Fong, L. G., Bensadouen, A., Jørgensen, T. J. D., Young, S. G. & Ploug, Michael, 2016, In: eLife. 5, 24 p., e12095.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Mapping the topographic epitope landscape on the urokinase plasminogen activator receptor (uPAR) by surface plasmon resonance and X-ray crystallography
Zhao, B., Gandhi, S., Yuan, C., Luo, Z., Li, R., Gårdsvoll, Henrik, de Lorenzi, V., Sidenius, N., Huang, M. & Ploug, Michael, Dec 2015, In: Data in Brief. 5, p. 107-13 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Heterogeneity in the properties of mutant secreted lymphocyte antigen 6/urokinase receptor-related protein 1 (SLURP1) in Mal de Meleda
Adeyo, O., Oberer, M., Ploug, Michael, Fong, L. G., Young, S. G. & Beigneux, A. P., Oct 2015, In: British Journal of Dermatology. 173, 4, p. 1066-9 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
New 177-lutetium labeled urokinase-type plasminogen activator receptor binding peptide conjugate, useful for treating cancer such as colorectal cancer, prostate cancer, neuroendocrine tumors, brain tumors, breast tumors and ovarian tumors
Kjær, Andreas, Persson, M. & Ploug, Michael, 8 Jul 2015, IPC No. C07K 16/ 30 A I, Patent No. CN104768573, Priority date 3 May 2013, Priority No. WO2013DK50126Research output: Patent
- Published
Urokinase receptor cleavage correlates with tumor volume in a transgenic mouse model of breast cancer
Thurison, T., Almholt, K., Gårdsvoll, Henrik, Ploug, Michael, Høyer-Hansen, G. & Lund, I. K., 25 Mar 2015, In: Molecular Carcinogenesis.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stabilizing a Flexible Interdomain Hinge Region Harboring the SMB Binding Site Drives uPAR into Its Closed Conformation
Zhao, B., Gandhi, S., Yuan, C., Luo, Z., Li, R., Gårdsvoll, Henrik, de Lorenzi, V., Sidenius, N., Huang, M. & Ploug, Michael, Mar 2015, In: Journal of Molecular Biology. 427, 6B, p. 1389-1403 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GPIHBP1 Missense Mutations Often Cause Multimerization of GPIHBP1 and Thereby Prevent Lipoprotein Lipase Binding
Beigneux, A. P., Fong, L. G., Bensadoun, A., Davies, B. S., Oberer, M., Gårdsvoll, Henrik, Ploug, Michael & Young, S. G., 2015, In: Circulation Research. 116, 4, p. 624-632 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
First-in-human uPAR PET: Imaging of Cancer Aggressiveness
Persson, M., Skovgaard, D., Brandt-Larsen, M., Christensen, C., Madsen, J., Nielsen, Carsten Haagen, Røndbjerg, T. T., Klausen, Thomas Levin, Holm, S., Loft, A., Berthelsen, A. K., Ploug, Michael, Pappot, H., Brasso, K., Kroman, Niels Thorndahl, Højgaard, Liselotte & Kjær, Andreas, 2015, In: Theranostics. 5, 12, p. 1303-16 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protein-binding RNA aptamers affect molecular interactions distantly from their binding sites
Dupont, D. M., Thuesen, C. K., Bøtkjær, K. A., Behrens, M. A., Dam, K., Sørensen, H. P., Pedersen, J., Ploug, Michael, Jensen, J. K. & Andreasen, P. A., 2015, In: PLOS ONE. 10, 4, 22 p., e0119207.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stepping up the tension in uPAR-mediated signaling by integrins
Ploug, Michael, 2015Research output: Other contribution › Net publication - Internet publication › Research
- 2014
- Published
C4.4A as a biomarker in pulmonary adenocarcinoma and squamous cell carcinoma
Jacobsen, B., Kriegbaum, M. C., Santoni Rugiu, Eric & Ploug, Michael, 10 Oct 2014, In: World Journal of Clinical Oncology. 5, 4, p. 621-32 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
uPAR Targeted Radionuclide Therapy with 177Lu-DOTA-AE105 Inhibits Dissemination of Metastatic Prostate Cancer
Persson, M., Stræde, Karina, Rasmussen, P., Brandt-Larsen, M., Madsen, J., Ploug, Michael & Kjær, Andreas, 4 Aug 2014, In: Molecular Pharmaceutics. 11, 8, p. 2796–2806 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multimerization of GPIHBP1 and Familial Chylomicronemia from a Serine-to-Cysteine Substitution in GPIHBP1's Ly6 Domain
Plengpanich, W., Young, S. G., Khovidhunkit, W., Bensadoun, A., Karnman, H., Ploug, Michael, Gardsvoll, H., Leung, C. S., Adeyo, O., Larsson, M., Muanpetch, S., Charoen, S., Fong, L. G., Niramitmahapanya, S. & Beigneux, A. P., 11 Jul 2014, In: The Journal of Biological Chemistry. 289, p. 19491-19499Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Electrochemical reduction of disulfide-containing proteins for hydrogen/deuterium exchange monitored by mass spectrometry
Mysling, S., Salbo, R., Ploug, Michael & Jørgensen, T. J. D., 7 Jan 2014, In: Analytical Chemistry. 86, 1, p. 340-5 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Administration of Recombinant Soluble Urokinase Receptor Per Se Is Not Sufficient to Induce Podocyte Alterations and Proteinuria in Mice
Cathelin, D., Placier, S., Ploug, Michael, Verpont, M., Vandermeersch, S., Luque, Y., Hertig, A., Rondeau, E. & Mesnard, L., 2014, In: Journal of the American Society of Nephrology. 25, 8, p. 1662-1668 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
C4.4A som biomarkør for solid tumorvækst og dårlig prognose i patienter med lungeadenokarcinom
Jacobsen, B., Santoni-Rugiu, E. & Ploug, Michael, 2014, In: Best Practice Onkologie. 4, p. 32-35Research output: Contribution to journal › Review › Research
- Published
Expression of the Ly6/uPAR-domain proteins C4.4A and Haldisin in non-invasive and invasive skin lesions
Kriegbaum, M. C., Clausen, O. P. F., Lærum, O. D. & Ploug, Michael, 2014, In: Journal of Histochemistry and Cytochemistry. 63, 2, p. 142-154 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tousled-like kinases phosphorylate Asf1 to promote histone supply during DNA replication
Kamalyukova, I. M., Young, C., Strømme, C. B., Ménard, Patrice, Jasencakova, Zuzana, Mejlvang, J., Ask, K., Ploug, Michael, Nielsen, Michael Lund, Jensen, O. N. & Groth, Anja, 2014, In: Nature Communications. 5, p. 3394Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
The urokinase receptor homolog Haldisin is a novel differentiation marker of stratum granulosum in squamous epithelia
Gårdsvoll, Henrik, Kriegbaum, M. C., Hertz, Emil Peter Thrane, Alpízar-Alpízar, W. & Ploug, Michael, Nov 2013, In: Journal of Histochemistry and Cytochemistry. 61, 11, p. 802-13 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Targeting of peptide conjugated magnetic nanoparticles to urokinase plasminogen activator receptor (uPAR) expressing cells
Hansen, L., Larsen, E. K. U., Nielsen, E. H., Iversen, F. H., Liu, Z., Thomsen, K. S., Pedersen, M., Skrydstrup, T., Nielsen, N. C., Ploug, Michael & Kjems, J., 7 Sep 2013, In: Nanoscale. 5, 17, p. 8192-201 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ly6/uPAR-related protein C4.4A as a marker of solid growth pattern and poor prognosis in lung adenocarcinoma
Jacobsen, B., Muley, T., Meister, M., Dienemann, H., Christensen, I. J., Santoni Rugiu, Eric, Lærum, O. D. & Ploug, Michael, Feb 2013, In: Journal of Thoracic Oncology. 8, 2, p. 152-60 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Improved PET Imaging of uPAR expression using new Cu-64-labeled cross-bridged peptide ligands: comparative in vitro and in vivo studies
Persson, M., Hosseini, M., Madsen, J., Jørgensen, T. J. D., Jensen, Knud Jørgen, Kjær, Andreas & Ploug, Michael, 2013, In: Theranostics. 3, 9, p. 618-632 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure-driven design of radionuclide tracers for non-invasive imaging of uPAR and targeted radiotherapy. The tale of a synthetic peptide antagonist
Ploug, Michael, 2013, In: Theranostics. 3, 7, p. 467-76 10 p.Research output: Contribution to journal › Review › Research › peer-review
- 2012
- Published
Targeting tumor cell invasion and dissemination in vivo by an aptamer that inhibits urokinase-type plasminogen activator through a novel multifunctional mechanism
Botkjaer, K. A., Deryugina, E. I., Dupont, D. M., Gårdsvoll, Henrik, Bekes, E. M., Thuesen, C. K., Chen, Z., Chen, Z., Ploug, Michael, Quigley, J. P. & Andreasen, P. A., Dec 2012, In: Molecular cancer research : MCR. 10, 12, p. 1532-43 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hydrogen/deuterium exchange mass spectrometry reveals specific changes in the local flexibility of plasminogen activator inhibitor 1 upon binding to the somatomedin B domain of vitronectin
Trelle, M. B., Hirschberg, D., Jansson, A., Ploug, Michael, Roepstorff, P., Andreasen, P. A. & Jørgensen, Thomas, 16 Oct 2012, In: Biochemistry. 51, 41, p. 8256-66 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
New peptide receptor radionuclide therapy of invasive cancer cells: in vivo studies using 177Lu-DOTA-AE105 targeting uPAR in human colorectal cancer xenografts
Persson, M., Rasmussen, P., Madsen, J., Ploug, Michael & Kjær, Andreas, Oct 2012, In: Nuclear Medicine and Biology. 39, 7, p. 962-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Erratum: Crystal structure of the urokinase receptor in a ligand-free form (Journal of Molecular Biology (2012) 416 (629-641))
Xu, X., Gårdsvoll, Henrik, Yuan, C., Lin, L., Ploug, Michael & Huang, M., 7 Sep 2012, In: Journal of Molecular Biology. 422, 1, 1 p.Research output: Contribution to journal › Comment/debate › Research
- Published
Expression of C4.4A in precursor lesions of pulmonary adenocarcinoma and squamous cell carcinoma
Jacobsen, B., Santoni Rugiu, Eric, Illemann, M., Kriegbaum, M. C., Laerum, O. D. & Ploug, Michael, 1 Jun 2012, In: International journal of cancer. Journal international du cancer. 130, 11, p. 2734-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
68Ga-labeling and in vivo evaluation of a uPAR binding DOTA- and NODAGA-conjugated peptide for PET imaging of invasive cancers
Persson, M., Madsen, J., Østergaard, S., Ploug, Michael & Kjær, Andreas, May 2012, In: Nuclear Medicine and Biology. 39, 4, p. 560-569 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Crystal structure of the urokinase receptor in a ligand-free form
Xu, X., Gårdsvoll, Henrik, Yuan, C., Lin, L., Ploug, Michael & Huang, M., 9 Mar 2012, In: Journal of Molecular Biology. 416, 5, p. 629-41 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
C4.4A er en ny biomarkør i ikke-småcellet lungekræft
Kriegbaum, M. C., Jacobsen, B., Santoni-Rugiu, E. & Ploug, Michael, 2012, In: Best Practice Onkologie. 2, 5, p. 58-61Research output: Contribution to journal › Review › Research
- Published
Quantitative PET of human urokinase-type plasminogen activator receptor with 64Cu-DOTA-AE105: implications for visualizing cancer invasion
Persson, M., Madsen, J., Østergaard, S., Wessel, Mette Munk, Jørgensen, Jesper Tranekjær, Stræde, Karina, Lehmann, C., Ploug, Michael & Kjær, Andreas, 2012, In: Journal of Nuclear Medicine. 53, 1, p. 138-45 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Urokinase-type plasminogen activator-like proteases in teleosts lack genuine receptor-binding epidermal growth factor-like domains
Bager, R., Kristensen, T. K., Jensen, J., Szczur, A., Christensen, A., Andersen, L., Johansen, J. S., Larsen, N., Baatrup, E., Huang, M., Ploug, Michael & Andreasen, P. A., 2012, In: The Journal of Biological Chemistry. 287, 33, p. 27526-27536 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
Rational targeting of the urokinase receptor (uPAR): development of antagonists and non-invasive imaging probes
Kriegbaum, M. C., Persson, M., Haldager, L., Alpizar, W. E. A., Jacobsen, B., Gårdsvoll, H., Kjær, Andreas & Ploug, Michael, Nov 2011, In: Current Drug Targets. 12, 12, p. 1711-1728 18 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Plasmodium ookinetes coopt mammalian plasminogen to invade the mosquito midgut
Ghosh, A. K., Coppens, I., Gårdsvoll, Henrik, Ploug, Michael & Jacobs-Lorena, M., 11 Oct 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 41, p. 17153-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Conformational regulation of urokinase receptor function: impact of receptor occupancy and epitope-mapped monoclonal antibodies on lamellipodia induction
Gårdsvoll, Henrik, Jacobsen, B., Kriegbaum, M. C., Behrendt, Niels, Engelholm, Lars Henning, Østergaard, S. & Ploug, Michael, 23 Sep 2011, In: The Journal of Biological Chemistry. 286, 38, p. 33544-56 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expression of C4.4A, a structural uPAR homolog, reflects squamous epithelial differentiation in the adult mouse and during embryogenesis
Kriegbaum, M. C., Jacobsen, B., Hald, A. & Ploug, Michael, 1 Feb 2011, In: Journal of Histochemistry and Cytochemistry. 59, 2, p. 188-201 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
C4.4A IS A PROGNOSTIC INDICATOR IN NON-SMALL CELL LUNG CANCER PATIENTS WITH ADENOCARCINOMAS
Jacobsen, B., Muley, T., Meister, M., Dienemann, H., Christensen, I. J., Santoni Rugiu, Eric, Laerum, O. D. & Ploug, Michael, 2011, In: Journal of Thoracic Oncology.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
C4.4A as a biomarker for poor prognosis in non-small cell lung cancer patients with adenocarcinomas
Jacobsen, B., Muley, T., Meister, M., Dienemann, H., Christensen, I. J., Santoni Rugiu, Eric, Laerum, O. D. & Ploug, Michael, 2011, In: European Journal of Cancer.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mimicry of the regulatory role of urokinase in lamellipodia formation by introduction of a non-native interdomain disulfide bond in its receptor
Gårdsvoll, Henrik, Kjærgaard, M., Jacobsen, B., Kriegbaum, M. C., Huang, M. & Ploug, Michael, 2011, In: Journal of Biological Chemistry. 286, 50, p. 43515-26 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteasernes veje og vildveje
Andreasen, P., Kjaer, A., Persson, M. & Ploug, Michael, 2011, In: Aktuel Naturvidenskab. 6, p. 24-27Research output: Contribution to journal › Review › Research
- 2010
- Published
INDUCTION AND/OR MAINTENANCE OF TUMOR DORMANCY BY DISRUPTION OF UROKINASE PLASMINOGEN ACTIVATOR RECEPTOR-INTEGRIN INTERACTION
Ossowski, L., Chaurasia, P., Aguirre-Ghiso Julio, A., Zhou, M. & Ploug, Michael, 30 Sep 2010, IPC No. G06G 7/ 60 A I, Patent No. US2010249184, Priority date 17 Mar 2008, Priority No. US20080531502Research output: Patent
- Published
Selective abrogation of the uPA-uPAR interaction in vivo reveals a novel role in suppression of fibrin-associated inflammation
Connolly, B. M., Choi, E. Y., Gårdsvoll, Henrik, Bey, A. L., Currie, B. M., Chavakis, T., Liu, S., Molinolo, A., Ploug, Michael, Leppla, S. H. & Bugge, T. V., 2 Sep 2010, In: Blood Weekly. 116, 9, p. 1593-603 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure-based engineering of species selectivity in the interaction between urokinase and its receptor: implication for preclinical cancer therapy
Lin, L., Gårdsvoll, Henrik, Huai, Q., Huang, M. & Ploug, Michael, 2 Apr 2010, In: Journal of Biological Chemistry. 285, 14, p. 10982-92 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
Specific recognition of the C-terminal end of A beta 42 by a high affinity monoclonal antibody
Axelsen, T. V., Holm, A., Birkelund, S., Christiansen, G., Ploug, Michael & Holm, I. E., Jul 2009, In: Molecular Immunology. 46, 11-12, p. 2267-73 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interactions of plasminogen activator inhibitor-1 with vitronectin involve an extensive binding surface and induce mutual conformational rearrangements
Blouse, G. E., Dupont, D. M., Schar, C. R., Jensen, J. K., Minor, K. H., Anagli, J. Y., Gårdsvoll, Henrik, Ploug, Michael, Peterson, C. B. & Andreasen, P. A., 3 Mar 2009, In: Biochemistry. 48, 8, p. 1723-35 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expression of C4.4A in precursor lesions of non-small cell lung cancer
Jacobsen, B., Santoni Rugiu, Eric, Illemann, M., Laerum, O. D. & Ploug, Michael, 2009, In: Journal of Thoracic Oncology.Research output: Contribution to journal › Journal article › Research › peer-review
PLAUR (Plasminogen activator, urokinase receptor
Jacobsen, B., Illemann, M. & Ploug, Michael, 2009Research output: Other contribution › Net publication - Internet publication › Research › peer-review
- 2008
- Published
Imaging of urokinase-type plasminogen activator receptor expression using a 64Cu-labeled linear peptide antagonist by microPET
Li, Z., Niu, G., Wang, H., He, L., Yang, L., Ploug, Michael & Chen, X., 1 Aug 2008, In: Clinical Cancer Research. 14, 15, p. 4758-66 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A composite role of vitronectin and urokinase in the modulation of cell morphology upon expression of the urokinase receptor
Hillig, T., Engelholm, Lars Henning, Ingvarsen, S., Madsen, Daniel Hargbøl, Gårdsvoll, Henrik, Larsen, J. K., Ploug, Michael, Danø, K., Kjøller, L. & Behrendt, Niels, 30 May 2008, In: Journal of Biological Chemistry. 283, 22, p. 15217-15223 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Altered expression of the urokinase receptor homologue, C4.4A, in invasive areas of human esophageal squamous cell carcinoma
Hansen, L. V., Laerum, O. D., Illemann, M., Nielsen, B. S. & Ploug, Michael, 15 Feb 2008, In: International Journal of Cancer. Supplement. 122, 4, p. 734-41 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hydrogen atom scrambling in selectively labeled anionic peptides upon collisional activation by MALDI tandem time-of-flight mass spectrometry
Bache, N., Rand, Kasper Dyrberg, Roepstorff, P., Ploug, Michael & Jørgensen, T., 2008, In: Journal of The American Society for Mass Spectrometry. 19, 12, p. 1719-25 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
LYPD3 (LY6/PLAUR domain containing 3
Jacobsen, B. & Ploug, Michael, 2008Research output: Other contribution › Net publication - Internet publication › Research › peer-review
Structure and inhibition of the urokinase-type plasminogen activator receptor(uPAR)
Jacobsen, B., Kjaergaard, M., Gårdsvoll, H. & Ploug, Michael, 2008, The Cancer Degradome: Proteases and Cancer Biology. Edwards, D., Høyer-Hansen, G., Blasi, F. & Sloane, B. L. (eds.). Springer Verlag, p. 699-719Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Structure and ligand interactions of the urokinase receptor (uPAR)
Kjærgaard, M., Hansen, L. V., Jacobsen, B., Gårdsvoll, H. & Ploug, Michael, 2008, In: Frontiers in Bioscience. 13, p. 5441-5461 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The urokinase receptor and its structural homologue C4.4A in human cancer: expression, prognosis and pharmacological inhibition
Jacobsen, B. & Ploug, Michael, 2008, In: Current Medicinal Chemistry. 15, 25, p. 2559-73 15 p.Research output: Contribution to journal › Review › Research › peer-review
- 2007
- Published
Tumour cell expression of C4.4A, a structural homologue of the urokinase receptor, correlates with poor prognosis in non-small cell lung cancer
Hansen, L. V., Skov, B. G., Ploug, Michael & Pappot, Helle, Nov 2007, In: Lung Cancer. 58, 2, p. 260-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mapping of the vitronectin-binding site on the urokinase receptor: involvement of a coherent receptor interface consisting of residues from both domain I and the flanking interdomain linker region
Gårdsvoll, Henrik & Ploug, Michael, 4 May 2007, In: The Journal of Biological Chemistry. 282, 18, p. 13561-72 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A new tagging system for production of recombinant proteins in Drosophila S2 cells using the third domain of the urokinase receptor
Gårdsvoll, Henrik, Hansen, L. V., Jørgensen, Thomas & Ploug, Michael, Apr 2007, In: Protein Expression and Purification. 52, 2, p. 384-94 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
One-step affinity purification of recombinant urokinase-type plasminogen activator receptor using a synthetic peptide developed by combinatorial chemistry
Jacobsen, B., Gårdsvoll, Henrik, Juhl Funch, G., Ostergaard, S., Barkholt, V. & Ploug, Michael, Apr 2007, In: Protein Expression and Purification. 52, 2, p. 286-96 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
- Published
Characterization of the functional epitope on the urokinase receptor. Complete alanine scanning mutagenesis supplemented by chemical cross-linking
Gårdsvoll, Henrik, Gilquin, B., Le Du, M. H., Ménèz, A., Jørgensen, Thomas & Ploug, Michael, 14 Jul 2006, In: The Journal of Biological Chemistry. 281, 28, p. 19260-72 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A region in urokinase plasminogen receptor domain III controlling a functional association with alpha5beta1 integrin and tumor growth
Chaurasia, P., Aguirre-Ghiso, J., Liang, O. D., Gardsvoll, H., Ploug, Michael & Ossowski, L., 26 May 2006, In: The Journal of Biological Chemistry. 281, 21, p. 14852-63 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Peptide antagonists of the human urokinase receptor and method for selecting them
Ploug, Michael, Oestergaard, S., Holst-Hansen, C., Stephens, R., Danoe, K. & Holm, A., 11 Apr 2006, IPC No. A61K 38/ 00 A N, Patent No. US7026282, Priority date 1 Jul 1999, Priority No. WO1999DK00377Research output: Patent
Plasminogen activation independent of uPA and tPA maintains wound healing in gene-deficient mice
Lund, L. R., Green, K. A., Stoop, A. A., Ploug, Michael, Almholt, K., Lilla, J., Nielsen, B. S., Christensen, I. J., Craik, C. S., Werb, Z., Danø, K. & Rømer, J., 2006, In: EMBO Journal. 25, 12, p. 2686-97 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2005
- Published
Collisional activation by MALDI tandem time-of-flight mass spectrometry induces intramolecular migration of amide hydrogens in protonated peptides
Jørgensen, Thomas, Bache, N., Roepstorff, P., Gårdsvoll, Henrik & Ploug, Michael, Dec 2005, In: Molecular and Cellular Proteomics. 4, 12, p. 1910-9 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Crystal structure of the human urokinase plasminogen activator receptor bound to an antagonist peptide
Llinas, P., Le Du, M. H., Gårdsvoll, Henrik, Danø, K., Ploug, Michael, Gilquin, B., Stura, E. A. & Ménèz, A., 4 May 2005, In: E M B O Journal. 24, 9, p. 1655-63 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intramolecular migration of amide hydrogens in protonated peptides upon collisional activation
Jørgensen, Thomas, Gårdsvoll, Henrik, Ploug, Michael & Roepstorff, P., 2 Mar 2005, In: Journal of the American Chemical Society. 127, 8, p. 2785-93 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasminogen activation and cancer
Danø, K., Behrendt, N., Hoyer-Hansen, G., Johnsen, M., Lund, L. R., Ploug, Michael & Nielsen, J. R., 2005, In: Thrombosis and Haemostasis. 93, 4, p. 676-681 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2004
- Published
Dynamics of urokinase receptor interaction with Peptide antagonists studied by amide hydrogen exchange and mass spectrometry
Jørgensen, Thomas, Gårdsvoll, Henrik, Danø, K., Roepstorff, P. & Ploug, Michael, 30 Nov 2004, In: Biochemistry. 43, 47, p. 15044-57 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
IMMUNOASSAYS FOR THE DETECTION OF UROKINASE RECEPTOR FORMS
Piironen, T., Hoeyer-Hansen, G., Bruenner, N., Ploug, Michael, List, K., Laursen, B., Danoe, K., Liljas, H., Haese, A., Hartwig, H., Toernblom, M. & Gustafsson, O., 18 Nov 2004, IPC No. G06F 19/ 20 A N, Patent No. WO2004099780, Priority date 6 May 2003, Priority No. DK20030000676Research output: Patent
- Published
Specific immunoassays for detection of intact and cleaved forms of the urokinase receptor
Piironen, T., Laursen, B., Pass, J., List, K., Gårdsvoll, Henrik, Ploug, Michael, Danø, K. & Høyer-Hansen, G., Nov 2004, In: Clinical Chemistry. 50, 11, p. 2059-68 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural analysis and tissue localization of human C4.4A: a protein homologue of the urokinase receptor
Hansen, L. V., Gårdsvoll, Henrik, Nielsen, B. S., Lund, L. R., Danø, K., Jensen, O. N. & Ploug, Michael, 15 Jun 2004, In: Biochemical Journal. 380, Pt 3, p. 845-57 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of low-glycosylated forms of soluble human urokinase receptor expressed in Drosophila Schneider 2 cells after deletion of glycosylation-sites
Gårdsvoll, Henrik, Werner, F., Søndergaard, Leif, Danø, K. & Ploug, Michael, 2004, In: Protein Expression and Purification. 34, 2, p. 284-295 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The urokinase receptor as a potential target in cancer therapy
Romer, J., Nielsen, B. S. & Ploug, Michael, 2004, In: Current Pharmaceutical Design. 10, 19, p. 2359-76 18 p.Research output: Contribution to journal › Review › Research › peer-review
- 2003
- Published
Urokinase-type plasminogen activator receptor
Dano, K., Blasi, F., Roldan, Ann, L., Cubellis, Maria, V., Masucci, Maria, T., Appella, E., Schleuning, W-D., Behrendt, N., Ronne, E., Kristensen, P., Pollanen, J., Salonen, E-M., Stephens, Ross, W., Tapiovaara, H., Vaheri, A., Moller Lisbeth, B., Ellis, V., Lund Leif, R., Ploug, M., Pyke, C. & 1 others, , 6 Feb 2003, IPC No. A61K 38/ 00 A N, Patent No. US2003027981, Priority date 8 Jan 2001, Priority No. US20010755109Research output: Patent
- Published
Structure-function relationships in the interaction between the urokinase-type plasminogen activator and its receptor
Ploug, Michael, 2003, In: Current Pharmaceutical Design. 9, 19, p. 1499-528 30 p.Research output: Contribution to journal › Review › Research › peer-review
- 2002
Structural analysis of the interaction between urokinase-type plasminogen activator and its receptor: a potential target for anti-invasive cancer therapy
Ploug, Michael, Gårdsvoll, Henrik, Jørgensen, T. J. D., Lønborg Hansen, L. & Danø, K., Apr 2002, In: Biochemical Society Transactions. 30, 2, p. 177-183 7 p.Research output: Contribution to journal › Review › Research › peer-review
- 2001
Peptide-derived antagonists of the urokinase receptor. Affinity maturation by combinatorial chemistry, identification of functional epitopes, and inhibitory effect on cancer cell intravasation
Ploug, Michael, Østergaard, S., Gårdsvoll, Henrik, Kovalski, K., Holst-Hansen, C., Holm, A., Ossowski, L. & Danø, K., 9 Oct 2001, In: Biochemistry. 40, 40, p. 12157-68 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
The murine receptor for urokinase-type plasminogen activator is primarily expressed in tissues actively undergoing remodeling
Solberg, H., Ploug, Michael, Høyer-Hansen, G., Nielsen, B. S. & Lund, L. R., Feb 2001, In: Journal of Histochemistry and Cytochemistry. 49, 2, p. 237-46 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2000
Plasminogen-independent initiation of the pro-urokinase activation cascade in vivo. Activation of pro-urokinase by glandular kallikrein (mGK-6) in plasminogen-deficient mice
List, K., Jensen, O. N., Bugge, T. H., Lund, L. R., Ploug, Michael, Danø, K. & Behrendt, Niels, 25 Jan 2000, In: Biochemistry. 39, 3, p. 508-15 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1999
Mapping part of the functional epitope for ligand binding on the receptor for urokinase-type plasminogen activator by site-directed mutagenesis
Gårdsvoll, Henrik, Danø, K. & Ploug, Michael, 31 Dec 1999, In: The Journal of Biological Chemistry. 274, 53, p. 37995-8003 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vectors and methods for recombinant production of uPA-binding fragments of the human urokinase-type plasminogen receptor (uPAR)
Danoe, K., Blasi, F., Roldan, Ann, L., Cubellis, Maria, V., Masucci, Maria, T., Appella, E., Schleuning, W-D., Behrendt, N., Rønne, E., Kristensen, P., Pollanen, J., Salonen, E-M., Stephens, Ross, W., Tapiovaara, H., Vaheri, A., Moeller, Lisbeth, B., Ellis, V., Lund, Leif, R., Ploug, M., Pyke, C. & 1 others, , 6 Apr 1999, IPC No. A61K 38/ 00 A N, Patent No. US5891664, Priority date 6 Oct 1994, Priority No. US19940319052Research output: Patent
- 1998
Identification of specific sites involved in ligand binding by photoaffinity labeling of the receptor for the urokinase-type plasminogen activator. Residues located at equivalent positions in uPAR domains I and III participate in the assembly of a composite ligand-binding site
Ploug, Michael, 24 Nov 1998, In: Biochemistry. 37, 47, p. 16494-505 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Glycosylation profile of a recombinant urokinase-type plasminogen activator receptor expressed in Chinese hamster ovary cells
Ploug, Michael, Rahbek-Nielsen, H., Nielsen, P. F., Roepstorff, P. & Dano, K., 29 May 1998, In: The Journal of Biological Chemistry. 273, 22, p. 13933-43 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Photoaffinity labeling of the human receptor for urokinase-type plasminogen activator using a decapeptide antagonist. Evidence for a composite ligand-binding site and a short interdomain separation
Ploug, Michael, Østergaard, S., Hansen, L. B. L., Holm, A. & Danø, K., 17 Mar 1998, In: Biochemistry. 37, 11, p. 3612-22 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1997
The intact urokinase receptor is required for efficient vitronectin binding: receptor cleavage prevents ligand interaction
Høyer-Hansen, G., Behrendt, Niels, Ploug, Michael, Danø, K. & Preissner, K. T., 22 Dec 1997, In: FEBS Letters. 420, 1, p. 79-85 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The rntact urokinase receptor is required for high affinity vitronectin binding: receptor cleavage prevents ligand interaction
GunillaHaver-Hansjan, Behrendt, Niels, Ploug, Michael, Dana, K. & Preissner, K. T., 1 Dec 1997, In: Fibrinolysis and Proteolysis. 11, SUPPL. 3, 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
Cell-surface acceleration of urokinase-catalyzed receptor cleavage
Høyer-Hansen, G., Ploug, Michael, Behrendt, Niels, Rønne, Elsebeth & Danø, K., 15 Jan 1997, In: European Journal of Biochemistry. 243, 1-2, p. 21-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
Structure, function and expression on blood and bone marrow cells of the urokinase-type plasminogen activator receptor, uPAR
Plesner, T., Behrendt, Niels & Ploug, Michael, 1997, In: Stem Cells. 15, 6, p. 398-408 11 p.Research output: Contribution to journal › Review › Research › peer-review
- 1996
uPA binding sites on domain 2+3 on uPAR and antibodies reactive therewith
Pessara, U., Weidle, U., Koenig, B., Kohnert, U., Bartke, I., Dano, K., Ploug, Michael & Ellis, V., 10 Jan 1996, IPC No. C12R 1/ 91 A N, Patent No. EP0691350, Priority date 8 Jul 1994, Priority No. DK19940000831Research output: Patent
Gene expression and function of the cellular receptor for uPA (uPAR)
Ellis, V., Ploug, Michael, Plesner, T. & Danø, K., 1996, Fibrinolysis in Disease. Glas-Greenwalt, P. (ed.). CRC Press, p. 30-42Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- 1995
Chemical modification of the urokinase-type plasminogen activator and its receptor using tetranitromethane. Evidence for the involvement of specific tyrosine residues in both molecules during receptor-ligand interaction
Ploug, Michael, Rahbek-Nielsen, H., Ellis, V., Roepstorff, P. & Danø, K., 3 Oct 1995, In: Biochemistry. 34, 39, p. 12524-34 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1994
Ligand interaction between urokinase-type plasminogen activator and its receptor probed with 8-anilino-1-naphthalenesulfonate. Evidence for a hydrophobic binding site exposed only on the intact receptor
Ploug, Michael, Ellis, V. & Danø, K., 2 Aug 1994, In: Biochemistry. 33, 30, p. 8991-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Structure-function relationships in the receptor for urokinase-type plasminogen activator. Comparison to other members of the Ly-6 family and snake venom alpha-neurotoxins
Ploug, Michael & Ellis, V., 1 Aug 1994, In: FEBS Letters. 349, 2, p. 163-8 6 p.Research output: Contribution to journal › Review › Research › peer-review
The receptor for urokinase-type plasminogen activator and urokinase is translocated from two distinct intracellular compartments to the plasma membrane on stimulation of human neutrophils
Plesner, T., Ploug, Michael, Ellis, V., Rønne, E., Høyer-Hansen, G., Wittrup, M., Pedersen, T. L., Tscherning, T., Danø, K. & Hansen, N. E., 1 Feb 1994, In: Blood. 83, 3, p. 808-15 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantitation of the receptor for urokinase plasminogen activator by enzyme-linked immunosorbent assay
Rønne, Elsebeth, Behrendt, Niels, Ploug, Michael, Nielsen, H. J., Wöllisch, E., Weidle, U., Danø, K. & Høyer-Hansen, G., 3 Jan 1994, In: Journal of Immunological Methods. 167, 1-2, p. 91-101 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
The urokinase receptor. Protein structure and role in plasminogen activation and cancer invasion
Danø, K., Behrendt, Niels, Brünner, N., Ellis, V., Ploug, Michael & Oyke, C., 1994, In: Fibrinolysis. 8, Supplement 1, p. 189-203Research output: Contribution to journal › Review › Research › peer-review
- 1993
Localization of the disulfide bonds in the NH2-terminal domain of the cellular receptor for human urokinase-type plasminogen activator. A domain structure belonging to a novel superfamily of glycolipid-anchored membrane proteins
Ploug, Michael, Kjalke, M., Rønne, E., Weidle, U., Høyer-Hansen, G. & Danø, K., 15 Aug 1993, In: The Journal of Biological Chemistry. 268, 23, p. 17539-46 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cellular receptor for urokinase-type plasminogen activator: protein structure
Behrendt, Niels, Ploug, Michael, Rønne, Elsebeth, Høyer-Hansen, G. & Danø, K., 1993, Methods of Enzymology. Vol. 223. p. 207-22 16 p. (Methods in Enzymology).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- 1992
Urokinase plasminogen activator cleaves its cell surface receptor releasing the ligand-binding domain
Høyer-Hansen, G., Rønne, E., Solberg, H., Behrendt, Niels, Ploug, Michael, Lund, L. R., Ellis, V. & Danø, K., 5 Sep 1992, In: The Journal of Biological Chemistry. 267, 25, p. 18224-18229 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
A soluble form of the glycolipid-anchored receptor for urokinase-type plasminogen activator is secreted from peripheral blood leukocytes from patients with paroxysmal nocturnal hemoglobinuria
Ploug, Michael, Eriksen, J., Plesner, T., Hansen, N. E. & Danø, K., 1 Sep 1992, In: European Journal of Biochemistry. 208, 2, p. 397-404 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Structural requirements for glycosyl-phosphatidylinositol-anchor attachment in the cellular receptor for urokinase plasminogen activator
Møller, L. B., Ploug, Michael & Blasi, F., 1 Sep 1992, In: European Journal of Biochemistry. 208, 2, p. 493-500 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Identification and characterization of the murine cell surface receptor for the urokinase-type plasminogen activator
Solberg, H., Løber, D., Eriksen, J., Ploug, Michael, Rønne, E., Behrendt, Niels, Danø, K. & Høyer-Hansen, G., 15 Apr 1992, In: European Journal of Biochemistry. 205, 2, p. 451-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
The receptor for urokinase-type plasminogen activator is deficient on peripheral blood leukocytes in patients with paroxysmal nocturnal hemoglobinuria
Ploug, Michael, Plesner, T., Rønne, E., Ellis, V., Høyer-Hansen, G., Hansen, N. E. & Danø, K., 15 Mar 1992, In: Blood. 79, 6, p. 1447-55 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
In situ alkylation of cysteine residues in a hydrophobic membrane protein immobilized on polyvinylidene difluoride membranes by electroblotting prior to microsequence and amino acid analysis
Ploug, Michael, Stoffer, B. B. & Jensen, A. L., Mar 1992, In: Electrophoresis. 13, 3, p. 148-53 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1991
- Published
Cell-induced potentiation of the plasminogen activation system is abolished by a monoclonal antibody that recognizes the NH2-terminal domain of the urokinase receptor
Rønne, Elsebeth, Behrendt, Niels, Ellis, V., Ploug, Michael, Danø, K. & Høyer-Hansen, G., 19 Aug 1991, In: FEBS Letters. 288, 1-2, p. 233-6 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
Protein structure and membrane anchorage of the cellular receptor for urokinase-type plasminogen activator
Ploug, Michael, Behrendt, Niels, Løber, D. & Danø, K., Jul 1991, In: Seminars in Thrombosis and Hemostasis. 17, 3, p. 183-93 11 p.Research output: Contribution to journal › Review › Research › peer-review
Cellular receptor for urokinase plasminogen activator. Carboxyl-terminal processing and membrane anchoring by glycosyl-phosphatidylinositol
Ploug, Michael, Rønne, E., Behrendt, Niels, Jensen, A. L., Blasi, F. & Danø, K., 25 Jan 1991, In: The Journal of Biological Chemistry. 266, 3, p. 1926-33 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1990
The human receptor for urokinase plasminogen activator. NH2-terminal amino acid sequence and glycosylation variants
Behrendt, Niels, Rønne, Elsebeth, Ploug, Michael, Petri, T., Løber, D., Nielsen, L. S., Schleuning, W. D., Blasi, F., Appella, E. & Danø, K., 15 Apr 1990, In: The Journal of Biological Chemistry. 265, 11, p. 6453-60 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
The urokinase receptor and regulation of cell surface plasminogen activation
Blasi, F., Cubellis, M. V., Masucci, M. T., Møller, L. B., Olson, D. P., Pedersen, N., Behrendt, Niels, Ellis, V., Ploug, Michael, Rønne, E. & Danø, K., 1990, In: Cell Differentation and Development. 32, 3, p. 247-54Research output: Contribution to journal › Journal article › Research
- 1989
Determination of amino acid compositions and NH2-terminal sequences of peptides electroblotted onto PVDF membranes from tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis: application to peptide mapping of human complement component C3
Ploug, Michael, Jensen, Asger Lundorff & Barkholt, V., 15 Aug 1989, In: Analytical Biochemistry. 181, 1, p. 33-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1988
- Published
Carbohydrate as covalent crosslink in human inter-alpha-trypsin inhibitor: a novel plasma protein structure
Jessen, T. E., Faarvang, K. L. & Ploug, Michael, 28 Mar 1988, In: FEBS Letters. 230, 1-2, p. 195-200 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1987
- Published
Localization and functional significance of a polymorphic determinant in the third component of human complement
Behrendt, Niels, Hansen, Ole, Ploug, Michael, Barkholt, V. & Koch, C., Oct 1987, In: Molecular Immunology. 24, 10, p. 1097-103 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1985
- Published
Hemolytic plate assay for quantification of active human complement component C3 using methylamine-treated plasma as complement source
Ploug, Michael, Jessen, T. E., Welinder, K. G. & Barkholt, V., 1 May 1985, In: Analytical Biochemistry. 146, 2, p. 411-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 33978213
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Structure of the lipoprotein lipase-GPIHBP1 complex that mediates plasma triglyceride hydrolysis
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IRDye800CW labeled uPAR-targeting peptide for fluorescence-guided glioblastoma surgery: Preclinical studies in orthotopic xenografts
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