Michael Ploug

Michael Ploug

Group leader


  1. 2024
  2. Published

    CL-11 circulates in serum as functionally distinct isoforms

    Sutta, A., Leemans, N. N., Ploug, Michael, Rosbjerg, A., del Agua Villa, C., Pérez-Alós, L., Cyranka, L., Vincek, A. S., de Garay, T., Rivera, K. & Bayarri-Olmos, R., 2024, In: FASEB Journal. 38, 5, e23543.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Quantification of lipoprotein lipase in mouse plasma with a sandwich enzyme-linked immunosorbent assay

    Kimura, T., Miyashita, K., Fukamachi, I., Fukamachi, K., Ogura, K., Yokoyama, E., Tsunekawa, K., Nagasawa, T., Ploug, Michael, Yang, Y., Song, W., Young, S. G., Beigneux, A. P., Nakajima, K. & Murakami, M., 2024, In: Journal of Lipid Research. 65, 4, 7 p., 100532.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. 2023
  5. Published

    Hypertriglyceridemia in Apoa5-/- mice results from reduced amounts of lipoprotein lipase in the capillary lumen

    Yang, Y., Beigneux, A. P., Song, W., Nguyen, L. P., Jung, H., Tu, Y., Weston, T. A., Tran, C. M., Xie, K., Yu, R. G., Tran, A. P., Miyashita, K., Nakajima, K., Murakami, M., Chen, Y. Q., Zhen, E. Y., Kim, J. R., Kim, P. H., Birrane, G., Tontonoz, P. & 4 others, Ploug, Michael, Konrad, R. J., Fong, L. G. & Young, S. G., 2023, In: Journal of Clinical Investigation. 133, 23, 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Intracapillary LPL levels in brown adipose tissue, visualized with an antibody-based approach, are regulated by ANGPTL4 at thermoneutral temperatures

    Song, W., Yang, Y., Heizer, P., Tu, Y., Weston, T. A., Kim, J. R., Munguia, P., Jung, H., Fong, J. L. C., Tran, C., Ploug, Michael, Beigneux, A. P., Young, S. G. & Fong, L. G., 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 8, 11 p., e2219833120.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Inverse effects of APOC2 and ANGPTL4 on the conformational dynamics of lid-anchoring structures in lipoprotein lipase

    Kumari, Anni, Grønnemose, A. L., Kristensen, Kristian Kølby, Winther, Anne-Marie Lund, Young, S. G., Jørgensen, T. J. D. & Ploug, Michael, 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 18, e2221888120.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Targeted imaging of uPAR expression in vivo with cyclic AE105 variants

    Leth, Julie Maja, Newcombe, Estella Anne, Grønnemose, A. L., Jørgensen, Jesper Tranekjær, Qvist, K., Clausen, Anne Skovsbo, Knudsen, Line Bruhn Schneider, Kjær, Andreas, Kragelund, Birthe Brandt, Jørgensen, Thomas Jørgen Dyreborg & Ploug, Michael, 2023, In: Scientific Reports. 13, 17 p., 17248.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    The lipoprotein lipase that is shuttled into capillaries by GPIHBP1 enters the glycocalyx where it mediates lipoprotein processing

    Song, W., Beigneux, A. P., Weston, T. A., Chen, K., Yang, Y., Nguyen, L. P., Guagliardo, P., Jung, H., Tran, A. P., Tu, Y., Tran, C., Birrane, G., Miyashita, K., Nakajima, K., Murakami, M., Tontonoz, P., Jiang, H., Ploug, Michael, Fong, L. G. & Young, S. G., 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 44, 12 p., e2313825120.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2022
  11. Published

    A protein of capillary endothelial cells, GPIHBP1, is crucial for plasma triglyceride metabolism

    Young, S. G., Song, W., Yang, Y., Birrane, G., Jiang, H., Beigneux, A. P., Ploug, Michael & Fong, L. G., 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 36, 12 p., e2211136119.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    ANGPTL4: a new mode in the regulation of intravascular lipolysis

    Ploug, Michael, 2022, In: Current Opinion in Lipidology. 33, 2, p. 112-119

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Electrostatic sheathing of lipoprotein lipase is essential for its movement across capillary endothelial cells

    Song, W., Beigneux, A. P., Winther, A. M. L., Kristensen, K. K., Grønnemose, A. L., Yang, Y., Tu, Y., Munguia, P., Morales, J., Jung, H., De Jong, P. J., Jung, C. J., Miyashita, K., Kimura, T., Nakajima, K., Murakami, M., Birrane, G., Jiang, H., Tontonoz, P., Ploug, M. & 2 others, Fong, L. G. & Young, S. G., 2022, In: Journal of Clinical Investigation. 132, 5, 15 p., e157500.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. 2021
  15. Published

    ANGPTL4 sensitizes lipoprotein lipase to PCSK3 cleavage by catalyzing its unfolding

    Winther, Anne-Marie Lund, Kumari, Anni, Young, S. G. & Ploug, Michael, 2021, In: Journal of Lipid Research. 62, 2 p., 100071.

    Research output: Contribution to journalComment/debateResearch

  16. Published

    Disorder in a two-domain neuronal Ca2+-binding protein regulates domain stability and dynamics using ligand mimicry

    Staby, L., Kemplen, K. R., Stein, Amelie, Ploug, Michael, Clarke, J., Skriver, Karen, Heidarsson, P. O. & Kragelund, Birthe Brandt, 2021, In: Cellular and molecular life sciences : CMLS. 78, p. 2263-2278 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Expression and one-step purification of active LPL contemplated by biophysical considerations

    Winther, Anne-Marie Lund, Kristensen, Kristian Kølby, Kumari, Anni & Ploug, Michael, 2021, In: Journal of Lipid Research. 62, 13 p., 100149.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    GPIHBP1 and ANGPTL4 Utilize Protein Disorder to Orchestrate Order in Plasma Triglyceride Metabolism and Regulate Compartmentalization of LPL Activity

    Kristensen, Kristian Kølby, Leth-Espensen, K. Z., Kumari, Anni, Grønnemose, A. L., Winther, Anne-Marie Lund, Young, S. G. & Ploug, Michael, 2021, In: Frontiers in Cell and Developmental Biology. 9, 20 p., 702508.

    Research output: Contribution to journalReviewResearchpeer-review

  19. Published

    IRDye800CW labeled uPAR-targeting peptide for fluorescence-guided glioblastoma surgery: Preclinical studies in orthotopic xenografts

    Kurbegovic, Sorel, Stræde, Karina, Sørensen, K. K., Leth, Julie Maja, Willemoe, G. L., Christensen, Anders, Adams, Yvonne, Jensen, Anja Ramstedt, von Buchwald, Christian, Skjøth-rasmussen, J., Ploug, Michael, Jensen, Knud Jørgen & Kjær, Andreas, 2021, In: Theranostics. 11, 15, p. 7159-7174 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Optimization and Evaluation of Al18F Labeling Using a NOTA—or RESCA1-Conjugated AE105 Peptide Antagonist of uPAR

    Jeppesen, T. E., Simón, M., Torp, J., Knudsen, Line Bruhn Schneider, Leth, Julie Maja, Crestey, F., Ploug, Michael, Jørgensen, Jesper Tranekjær, Madsen, J., Herth, Matthias Manfred & Kjær, Andreas, 2021, In: Frontiers in Nuclear Medicine. 1, 9 p., 799533.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Targeting the Urokinase-Type Plasminogen Activator Receptor (uPAR) in Human Diseases With a View to Non-invasive Imaging and Therapeutic Intervention

    Leth, Julie Maja & Ploug, Michael, 2021, In: Frontiers in Cell and Developmental Biology. 9, 20 p., 732015.

    Research output: Contribution to journalReviewResearchpeer-review

  22. Published

    The Importance of Lipoprotein Lipase Regulation in Atherosclerosis

    Kumari, Anni, Kristensen, Kristian Kølby, Ploug, Michael & Winther, Anne-Marie Lund, 2021, In: Biomedicines. 9, 7, 24 p., 782.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    The Urokinase Receptor (uPAR) as a “Trojan Horse” in Targeted Cancer Therapy: Challenges and Opportunities

    Metrangolo, Virginia, Ploug, Michael & Engelholm, Lars Henning, 2021, In: Cancers. 13, 21, 45 p., 5376.

    Research output: Contribution to journalReviewResearchpeer-review

  24. Published

    The intrinsic instability of the hydrolase domain of lipoprotein lipase facilitates its inactivation by ANGPTL4-catalyzed unfolding

    Leth-Espensen, K. Z., Kristensen, Kristian Kølby, Kumari, Anni, Winther, Anne-Marie Lund, Young, S. G., Jørgensen, T. J. D. & Ploug, Michael, 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 12, e2026650118.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. 2020
  26. Published

    ANGPTL4 inactivates lipoprotein lipase by catalyzing the irreversible unfolding of LPL's hydrolase domain

    Kristensen, Kristian Kølby, Leth-Espensen, K. Z., Young, S. G. & Ploug, Michael, 2020, In: Journal of Lipid Research. 61, 9, p. 1253

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Chylomicronemia From GPIHBP1 Autoantibodies Successfully Treated With Rituximab: A Case Report

    Lutz, J., Dunaj-Kazmierowska, M., Arcan, S., Kassner, U., Miyashita, K., Murakami, M., Ploug, Michael, Fong, L. G., Young, S. G., Nakajima, K. & Beigneux, A. P., 2020, In: Annals of Internal Medicine. 173, 9, p. 764-765

    Research output: Contribution to journalLetterResearchpeer-review

  28. Published

    Chylomicronemia from GPIHBP1 autoantibodies

    Miyashita, K., Lutz, J., Hudgins, L. C., Toib, D., Ashraf, A. P., Song, W., Murakami, M., Nakajima, K., Ploug, Michael, Fong, L. G., Young, S. G. & Beigneux, A. P., 2020, In: Journal of Lipid Research. 61, 11, p. 1365-1376

    Research output: Contribution to journalReviewResearchpeer-review

  29. Published

    Crystal Structures of Human C4.4A Reveal the Unique Association of Ly6/uPAR/α-neurotoxin Domain

    Jiang, Y., Lin, L., Chen, S., Jiang, L., Kriegbaum, M. C., Gårdsvoll, Henrik, Hansen, L. V., Li, J., Ploug, Michael, Yuan, C. & Huang, M., 2020, In: International Journal of Biological Sciences. 16, 6, p. 981-993 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Determination of Binding Kinetics of Intrinsically Disordered Proteins by Surface Plasmon Resonance

    Leth, Julie Maja & Ploug, Michael, 2020, Intrinsically Disorded Proteins. Kragelund, B. & Skriver, K. (eds.). Springer, Vol. 2141. p. 611-627 17 p. (Methods in molecular biology (Clifton, N.J.)).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  31. Published

    Efficient refolding and reconstitution of tissue factor into nanodiscs facilitates structural investigation of a multicomponent system on a lipid bilayer

    Tidemand, Frederik Grønbæk, Østergaard, H., Ploug, Michael, Kragelund, Birthe Brandt & Arleth, Lise, 2020, In: Biochimica et Biophysica Acta - Biomembranes. 1862, 6, 10 p., 183214.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Helicobacter pylori Colonization Drives Urokinase Receptor (uPAR) Expression in Murine Gastric Epithelium During Early Pathogenesis

    Alpízar-Alpízar, W., Skindersoe, M. E., Rasmussen, L., Kriegbaum, M. C., Christensen, I. J., Lund, I. K., Illemann, M., Laerum, O. D., Krogfelt, K. A., Andersen, L. P. & Ploug, Michael, 2020, In: Microorganisms. 8, 7, 1019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Intermittent chylomicronemia caused by intermittent GPIHBP1 autoantibodies

    Ashraf, A. P., Miyashita, K., Nakajima, K., Murakami, M., Hegele, R. A., Ploug, Michael, Fong, L. G., Young, S. G. & Beigneux, A. P., 2020, In: Journal of Clinical Lipidology. 14, 2, p. 197-200

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Small-Molecule Inhibition of the uPAR uPA Interaction by Conformational Selection

    Xu, D., Bum-Erdene, K., Leth, Julie Maja, Ghozayel, M. K., Ploug, Michael & Meroueh, S. O., 2020, In: ChemMedChem. 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    The structural basis for monoclonal antibody 5D2 binding to the tryptophan-rich loop of lipoprotein lipase

    Luz, J., Beigneux, A. P., Asamoto, D. K., He, C., Song, W., Allan, C. M., Morales, J. E., Tu, Y., Kwok, A., Cottle, T., Meiyappan, M., Fong, L. G., Kim, J., Ploug, Michael, Young, S. G. & Birrane, G., 2020, In: Journal of Lipid Research. 61, 10, p. 1347-1359

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Unfolding of monomeric lipoprotein lipase by ANGPTL4: Insight into the regulation of plasma triglyceride metabolism

    Kristensen, Kristian Kølby, Leth-Espensen, K. Z., Mertens, H. D. T., Birrane, G., Meiyappan, M., Olivecrona, G., Jørgensen, T. J. D., Young, S. G. & Ploug, Michael, 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 8, p. 4337-4346

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. 2019
  38. Published

    Crystal structure of the unoccupied murine urokinase-type plasminogen activator receptor (uPAR) reveals a tightly packed DII-DIII unit

    Liu, M., Hansen, G. H., Ploug, Michael, Hanlin, L., Jiang, L., Yuan, C., Li, J. & Huang, M., 2019, In: FEBS Letters. 593, 11, p. 1236-1247 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Did evolution create a flexible ligand-binding cavity in the urokinase receptor through deletion of a plesiotypic disulfide bond?

    Leth, Julie Maja, Mertens, H. D. T., Leth-Espensen, K. Z., Jørgensen, T. J. D. & Ploug, Michael, 2019, In: The Journal of Biological Chemistry. 294, 18, p. 7403-7418 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Evolution and Medical Significance of LU Domain-Containing Proteins

    Leth, Julie Maja, Leth-Espensen, K. Z., Kristensen, Kristian Kølby, Kumari, Anni, Winther, Anne-Marie Lund, Young, S. G. & Ploug, Michael, 2019, In: International Journal of Molecular Sciences. 20, 11, p. 1-20 20 p.

    Research output: Contribution to journalReviewResearchpeer-review

  41. Published

    GPIHBP1 and Lipoprotein Lipase, Partners in Plasma Triglyceride Metabolism

    Young, S. G., Fong, L. G., Beigneux, A. P., Allan, C. M., He, C., Jiang, H., Nakajima, K., Meiyappan, M., Birrane, G. & Ploug, Michael, 2019, In: Cell Metabolism. 30, 1, p. 51-65 15 p.

    Research output: Contribution to journalReviewResearchpeer-review

  42. Published

    GPIHBP1 autoantibody syndrome during interferon β1a treatment

    Eguchi, J., Miyashita, K., Fukamachi, I., Nakajima, K., Murakami, M., Kawahara, Y., Yamashita, T., Ohta, Y., Abe, K., Nakatsuka, A., Mino, M., Takase, S., Okazaki, H., Hegele, R. A., Ploug, Michael, Hu, X., Wada, J., Young, S. G. & Beigneux, A. P., 2019, In: Journal of Clinical Lipidology. 13, 1, p. 62-69 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Lipoprotein lipase is active as a monomer

    Beigneux, A. P., Allan, C. M., Sandoval, N. P., Cho, G. W., Heizer, P. J., Jung, R. S., Stanhope, K. L., Havel, P. J., Birrane, G., Meiyappan, M., Gill, J. E., Murakami, M., Miyashita, K., Nakajima, K., Ploug, Michael, Fong, L. G. & Young, S. G., 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 13, p. 6319-6328 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    On the mechanism of angiopoietin-like protein 8 for control of lipoprotein lipase activity

    Kovrov, O., Kristensen, Kristian Kølby, Larsson, E., Ploug, Michael & Olivecrona, G., 2019, In: Journal of Lipid Research. 60, 4, p. 783-793 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Origin and diversification of the plasminogen activation system among chordates

    Chana-Muñoz, A., Jendroszek, A., Sønnichsen, M., Wang, T., Ploug, Michael, Jensen, J. K., Andreasen, P. A., Bendixen, C. & Panitz, F., 2019, In: BMC Evolutionary Biology. 19, 1, p. 1-17 17 p., 27.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Peptide disc mediated control of membrane protein orientation in supported lipid bilayers for surface-sensitive investigations

    Luchini, A., Tidemand, Frederik Grønbæk, Johansen, Nicolai Tidemand, Campana, M., Sotres, J., Ploug, Michael, Cárdenas, M. & Arleth, Lise, 2019, In: Analytical Chemistry. 92, 1, p. 1081-1088

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Structure of the lipoprotein lipase-GPIHBP1 complex that mediates plasma triglyceride hydrolysis

    Birrane, G., Beigneux, A. P., Dwyer, B., Strack-Logue, B., Kristensen, Kristian Kølby, Francone, O. L., Fong, L. G., Mertens, H. D. T., Pan, C. Q., Ploug, Michael, Young, S. G. & Meiyappan, M., 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 5, p. 1723-1732 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    The PCNA interaction motifs revisited: thinking outside the PIP-box

    Prestel, Andreas, Wichmann, N., Martins, J. M., Marabini, R., Kassem, N., Broendum, S. S., Otterlei, M., Nielsen, Olaf, Willemoës, Martin, Ploug, Michael, Boomsma, Wouter & Kragelund, Birthe Brandt, 2019, In: Cellular and Molecular Life Sciences. 76, 24, p. 4923-4943

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. 2018
  50. Published

    NanoSIMS Analysis of Intravascular Lipolysis and Lipid Movement across Capillaries and into Cardiomyocytes

    He, C., Weston, T. A., Jung, R. S., Heizer, P., Larsson, M., Hu, X., Allan, C. M., Tontonoz, P., Reue, K., Beigneux, A. P., Ploug, Michael, Holme, A., Kilburn, M., Guagliardo, P., Ford, D. A., Fong, L. G., Young, S. G. & Jiang, H., 1 May 2018, In: Cell Metabolism. 27, 5, p. 1055-1066.e3 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    An enzyme-linked immunosorbent assay for measuring GPIHBP1 levels in human plasma or serum

    Miyashita, K., Fukamachi, I., Nagao, M., Ishida, T., Kobayashi, J., Machida, T., Nakajima, K., Murakami, M., Ploug, Michael, Beigneux, A. P., Young, S. G. & Nakajima, K., Jan 2018, In: Journal of Clinical Lipidology. 12, 1, p. 203-210 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    A disordered acidic domain in GPIHBP1 harboring a sulfated tyrosine regulates lipoprotein lipase

    Kristensen, Kristian Kølby, Midtgaard, S. R., Mysling, S., Kovrov, O., Hansen, L. B., Skar-Gislinge, Nicholas, Beigneux, A. P., Kragelund, Birthe Brandt, Olivecrona, G., Young, S. G., Jørgensen, T. J. D., Fong, L. G. & Ploug, Michael, 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 26, p. E6020-E6029 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. 2017
  54. Published

    Expression and crystallographic studies of the D1D2 domains of C4.4A, a homologous protein to the urokinase receptor

    Chen, S., Lin, L., Yuan, C., Gårdsvoll, Henrik, Kriegbaum, M. C., Ploug, Michael & Huang, M., 1 Aug 2017, In: Acta Crystallographica Section F: Structural Biology Communications. 73, 8, p. 486-490 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    GPIHBP1 autoantibodies in a patient with unexplained chylomicronemia

    Hu, X., Dallinga-Thie, G. M., Hovingh, G. K., Chang, S. Y., Sandoval, N. P., Dang, T. L. P., Fukamachi, I., Miyashita, K., Nakajima, K., Murakami, M., Fong, L. G., Ploug, Michael, Young, S. G. & Beigneux, A. P., 1 Jul 2017, In: Journal of Clinical Lipidology. 11, 4, p. 964-971 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Autoantibodies against GPIHBP1 as a Cause of Hypertriglyceridemia

    Beigneux, A. P., Miyashita, K., Ploug, M., Blom, J. D., Ai, M., Linton, M. F., Khovidhunkit, W., Dufour, R., Garg, A., McMahon, M. A., Pullinger, C. R., Sandoval, N. P., Hu, X., Allan, C. M., Larsson, M., Machida, T., Murakami, M., Reue, K., Tontonoz, P., Goldberg, I. J. & 5 others, Moulin, P., Charrière, S., Fong, L. G., Nakajima, K. & Young, S. G., 27 Apr 2017, In: New England Journal of Medicine. 376, 17, p. 1647-1658 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Mobility of “HSPG-bound” LPL explains how LPL is able to reach GPIHBP1 on capillaries

    Allan, C. M., Larsson, M., Jung, R. S., Ploug, Michael, Bensadoun, A., Beigneux, A. P., Fong, L. G. & Young, S. G., Jan 2017, In: Journal of Lipid Research. 58, 1, p. 216-225

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Monoclonal Antibodies That Bind to the Ly6 Domain of GPIHBP1 Abolish the Binding of LPL

    Hu, X., Sleeman, M. W., Miyashita, K., Linton, M. F., Allan, C. M., He, C., Larsson, M., Tu, Y., Sandoval, N. P., Jung, R. S., Mapar, A., Machida, T., Murakami, M., Nakajima, K., Ploug, Michael, Fong, L. G., Young, S. G. & Beigneux, A. P., Jan 2017, In: Journal of Lipid Research. 58, p. 208-215 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Expression of C4.4A in an in Vitro Human Tissue-Engineered Skin Model

    Jacobsen, B., Larouche, D., Rochette-Drouin, O., Ploug, Michael & Germain, L., 2017, In: BioMed Research International. 2017, 9 p., 2403072.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. 2016
  61. Published

    The angiopoietin-like protein ANGPTL4 catalyzes unfolding of the hydrolase domain in lipoprotein lipase and the endothelial membrane protein GPIHBP1 counteracts this unfolding

    Mysling, S., Kristensen, K. K., Larsson, M., Kovrov, O., Bensadouen, A., Jørgensen, T. J. D., Olivecrona, G., Young, S. G. & Ploug, Michael, 8 Dec 2016, In: eLife. 5, 18 p., e20958.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    A lipoprotein lipase (LPL)-specific monoclonal antibody, 88B8, that abolishes the binding of LPL to GPIHBP1

    Allan, C. M., Larsson, M., Hu, X., He, C., Jung, R. S., Mapar, A., Voss, C., Miyashita, K., Machida, T., Murakami, M., Nakajima, K., Bensadoun, A., Ploug, Michael, Fong, L. G., Young, S. G. & Beigneux, A. P., Oct 2016, In: Journal of Lipid Research. 57, 10, p. 1889-1898

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Tissue Inhibitor of Metalloproteinase-1 Is Confined to Tumor-Associated Myofibroblasts and Is Increased With Progression in Gastric Adenocarcinoma

    Alpízar-Alpízar, W., Lærum, O. D., Christensen, I. J., Ovrebo, K., Skarstein, A., Høyer-Hansen, G., Ploug, Michael & Illemann, M., Aug 2016, In: Journal of Histochemistry and Cytochemistry. 64, 8, p. 483-94 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    GPIHBP1 and Plasma Triglyceride Metabolism

    Fong, L. G., Young, S. G., Beigneux, A. P., Bensadoun, A., Oberer, M., Jiang, H. & Ploug, Michael, Jul 2016, In: Trends in Endocrinology and Metabolism. 27, 7, p. 455-69 15 p.

    Research output: Contribution to journalReviewResearchpeer-review

  65. Published

    C4.4A gene ablation is compatible with normal epidermal development and causes modest overt phenotypes

    Kriegbaum, M. C., Jacobsen, B., Fuchtbauer, A., Hansen, Gert Helge, Christensen, I. J., Friis, Carsten, Persson, M., Engelholm, Lars Henning, Madsen, A. N., Di Meo, I., Lund, I. K., Holst, Birgitte, Kjær, Andreas, Laerum, O. D., Fuchtbauer, E. & Ploug, Michael, 12 May 2016, In: Scientific Reports. 6, 25833.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Peptide-Based Optical uPAR Imaging for Surgery: In Vivo Testing of ICG-Glu-Glu-AE105

    Stræde, Karina, Christensen, Anders, Persson, M., Ploug, Michael & Kjær, Andreas, 2016, In: PloS one. 11, 2, 15 p., e0147428.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    The acidic domain of the endothelial membrane protein GPIHBP1 stabilizes lipoprotein lipase activity by preventing unfolding of its catalytic domain

    Mysling, S., Kristensen, K. K., Larsson, M., Beigneux, A. P., Gårdsvoll, Henrik, Fong, L. G., Bensadouen, A., Jørgensen, T. J. D., Young, S. G. & Ploug, Michael, 2016, In: eLife. 5, 24 p., e12095.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. 2015
  69. Published

    Mapping the topographic epitope landscape on the urokinase plasminogen activator receptor (uPAR) by surface plasmon resonance and X-ray crystallography

    Zhao, B., Gandhi, S., Yuan, C., Luo, Z., Li, R., Gårdsvoll, Henrik, de Lorenzi, V., Sidenius, N., Huang, M. & Ploug, Michael, Dec 2015, In: Data in Brief. 5, p. 107-13 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Heterogeneity in the properties of mutant secreted lymphocyte antigen 6/urokinase receptor-related protein 1 (SLURP1) in Mal de Meleda

    Adeyo, O., Oberer, M., Ploug, Michael, Fong, L. G., Young, S. G. & Beigneux, A. P., Oct 2015, In: British Journal of Dermatology. 173, 4, p. 1066-9 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published
  72. Published

    Urokinase receptor cleavage correlates with tumor volume in a transgenic mouse model of breast cancer

    Thurison, T., Almholt, K., Gårdsvoll, Henrik, Ploug, Michael, Høyer-Hansen, G. & Lund, I. K., 25 Mar 2015, In: Molecular Carcinogenesis.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Stabilizing a Flexible Interdomain Hinge Region Harboring the SMB Binding Site Drives uPAR into Its Closed Conformation

    Zhao, B., Gandhi, S., Yuan, C., Luo, Z., Li, R., Gårdsvoll, Henrik, de Lorenzi, V., Sidenius, N., Huang, M. & Ploug, Michael, Mar 2015, In: Journal of Molecular Biology. 427, 6B, p. 1389-1403 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    GPIHBP1 Missense Mutations Often Cause Multimerization of GPIHBP1 and Thereby Prevent Lipoprotein Lipase Binding

    Beigneux, A. P., Fong, L. G., Bensadoun, A., Davies, B. S., Oberer, M., Gårdsvoll, Henrik, Ploug, Michael & Young, S. G., 2015, In: Circulation Research. 116, 4, p. 624-632 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    First-in-human uPAR PET: Imaging of Cancer Aggressiveness

    Persson, M., Skovgaard, D., Brandt-Larsen, M., Christensen, C., Madsen, J., Nielsen, Carsten Haagen, Røndbjerg, T. T., Klausen, Thomas Levin, Holm, S., Loft, A., Berthelsen, A. K., Ploug, Michael, Pappot, H., Brasso, K., Kroman, Niels Thorndahl, Højgaard, Liselotte & Kjær, Andreas, 2015, In: Theranostics. 5, 12, p. 1303-16 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Protein-binding RNA aptamers affect molecular interactions distantly from their binding sites

    Dupont, D. M., Thuesen, C. K., Bøtkjær, K. A., Behrens, M. A., Dam, K., Sørensen, H. P., Pedersen, J., Ploug, Michael, Jensen, J. K. & Andreasen, P. A., 2015, In: PLOS ONE. 10, 4, 22 p., e0119207.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Stepping up the tension in uPAR-mediated signaling by integrins

    Ploug, Michael, 2015

    Research output: Other contributionNet publication - Internet publicationResearch

  78. 2014
  79. Published

    C4.4A as a biomarker in pulmonary adenocarcinoma and squamous cell carcinoma

    Jacobsen, B., Kriegbaum, M. C., Santoni Rugiu, Eric & Ploug, Michael, 10 Oct 2014, In: World Journal of Clinical Oncology. 5, 4, p. 621-32 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    uPAR Targeted Radionuclide Therapy with 177Lu-DOTA-AE105 Inhibits Dissemination of Metastatic Prostate Cancer

    Persson, M., Stræde, Karina, Rasmussen, P., Brandt-Larsen, M., Madsen, J., Ploug, Michael & Kjær, Andreas, 4 Aug 2014, In: Molecular Pharmaceutics. 11, 8, p. 2796–2806 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    Multimerization of GPIHBP1 and Familial Chylomicronemia from a Serine-to-Cysteine Substitution in GPIHBP1's Ly6 Domain

    Plengpanich, W., Young, S. G., Khovidhunkit, W., Bensadoun, A., Karnman, H., Ploug, Michael, Gardsvoll, H., Leung, C. S., Adeyo, O., Larsson, M., Muanpetch, S., Charoen, S., Fong, L. G., Niramitmahapanya, S. & Beigneux, A. P., 11 Jul 2014, In: The Journal of Biological Chemistry. 289, p. 19491-19499

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Electrochemical reduction of disulfide-containing proteins for hydrogen/deuterium exchange monitored by mass spectrometry

    Mysling, S., Salbo, R., Ploug, Michael & Jørgensen, T. J. D., 7 Jan 2014, In: Analytical Chemistry. 86, 1, p. 340-5 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Administration of Recombinant Soluble Urokinase Receptor Per Se Is Not Sufficient to Induce Podocyte Alterations and Proteinuria in Mice

    Cathelin, D., Placier, S., Ploug, Michael, Verpont, M., Vandermeersch, S., Luque, Y., Hertig, A., Rondeau, E. & Mesnard, L., 2014, In: Journal of the American Society of Nephrology. 25, 8, p. 1662-1668 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    C4.4A som biomarkør for solid tumorvækst og dårlig prognose i patienter med lungeadenokarcinom

    Jacobsen, B., Santoni-Rugiu, E. & Ploug, Michael, 2014, In: Best Practice Onkologie. 4, p. 32-35

    Research output: Contribution to journalReviewResearch

  85. Published

    Expression of the Ly6/uPAR-domain proteins C4.4A and Haldisin in non-invasive and invasive skin lesions

    Kriegbaum, M. C., Clausen, O. P. F., Lærum, O. D. & Ploug, Michael, 2014, In: Journal of Histochemistry and Cytochemistry. 63, 2, p. 142-154 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Tousled-like kinases phosphorylate Asf1 to promote histone supply during DNA replication

    Kamalyukova, I. M., Young, C., Strømme, C. B., Ménard, Patrice, Jasencakova, Zuzana, Mejlvang, J., Ask, K., Ploug, Michael, Nielsen, Michael Lund, Jensen, O. N. & Groth, Anja, 2014, In: Nature Communications. 5, p. 3394

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. 2013
  88. Published

    The urokinase receptor homolog Haldisin is a novel differentiation marker of stratum granulosum in squamous epithelia

    Gårdsvoll, Henrik, Kriegbaum, M. C., Hertz, Emil Peter Thrane, Alpízar-Alpízar, W. & Ploug, Michael, Nov 2013, In: Journal of Histochemistry and Cytochemistry. 61, 11, p. 802-13 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Targeting of peptide conjugated magnetic nanoparticles to urokinase plasminogen activator receptor (uPAR) expressing cells

    Hansen, L., Larsen, E. K. U., Nielsen, E. H., Iversen, F. H., Liu, Z., Thomsen, K. S., Pedersen, M., Skrydstrup, T., Nielsen, N. C., Ploug, Michael & Kjems, J., 7 Sep 2013, In: Nanoscale. 5, 17, p. 8192-201 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Ly6/uPAR-related protein C4.4A as a marker of solid growth pattern and poor prognosis in lung adenocarcinoma

    Jacobsen, B., Muley, T., Meister, M., Dienemann, H., Christensen, I. J., Santoni Rugiu, Eric, Lærum, O. D. & Ploug, Michael, Feb 2013, In: Journal of Thoracic Oncology. 8, 2, p. 152-60 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Improved PET Imaging of uPAR expression using new Cu-64-labeled cross-bridged peptide ligands: comparative in vitro and in vivo studies

    Persson, M., Hosseini, M., Madsen, J., Jørgensen, T. J. D., Jensen, Knud Jørgen, Kjær, Andreas & Ploug, Michael, 2013, In: Theranostics. 3, 9, p. 618-632 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Structure-driven design of radionuclide tracers for non-invasive imaging of uPAR and targeted radiotherapy. The tale of a synthetic peptide antagonist

    Ploug, Michael, 2013, In: Theranostics. 3, 7, p. 467-76 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

  93. 2012
  94. Published

    Targeting tumor cell invasion and dissemination in vivo by an aptamer that inhibits urokinase-type plasminogen activator through a novel multifunctional mechanism

    Botkjaer, K. A., Deryugina, E. I., Dupont, D. M., Gårdsvoll, Henrik, Bekes, E. M., Thuesen, C. K., Chen, Z., Chen, Z., Ploug, Michael, Quigley, J. P. & Andreasen, P. A., Dec 2012, In: Molecular cancer research : MCR. 10, 12, p. 1532-43 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Hydrogen/deuterium exchange mass spectrometry reveals specific changes in the local flexibility of plasminogen activator inhibitor 1 upon binding to the somatomedin B domain of vitronectin

    Trelle, M. B., Hirschberg, D., Jansson, A., Ploug, Michael, Roepstorff, P., Andreasen, P. A. & Jørgensen, Thomas, 16 Oct 2012, In: Biochemistry. 51, 41, p. 8256-66 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    New peptide receptor radionuclide therapy of invasive cancer cells: in vivo studies using 177Lu-DOTA-AE105 targeting uPAR in human colorectal cancer xenografts

    Persson, M., Rasmussen, P., Madsen, J., Ploug, Michael & Kjær, Andreas, Oct 2012, In: Nuclear Medicine and Biology. 39, 7, p. 962-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    Erratum: Crystal structure of the urokinase receptor in a ligand-free form (Journal of Molecular Biology (2012) 416 (629-641))

    Xu, X., Gårdsvoll, Henrik, Yuan, C., Lin, L., Ploug, Michael & Huang, M., 7 Sep 2012, In: Journal of Molecular Biology. 422, 1, 1 p.

    Research output: Contribution to journalComment/debateResearch

  98. Published

    Expression of C4.4A in precursor lesions of pulmonary adenocarcinoma and squamous cell carcinoma

    Jacobsen, B., Santoni Rugiu, Eric, Illemann, M., Kriegbaum, M. C., Laerum, O. D. & Ploug, Michael, 1 Jun 2012, In: International journal of cancer. Journal international du cancer. 130, 11, p. 2734-9 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    68Ga-labeling and in vivo evaluation of a uPAR binding DOTA- and NODAGA-conjugated peptide for PET imaging of invasive cancers

    Persson, M., Madsen, J., Østergaard, S., Ploug, Michael & Kjær, Andreas, May 2012, In: Nuclear Medicine and Biology. 39, 4, p. 560-569 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Crystal structure of the urokinase receptor in a ligand-free form

    Xu, X., Gårdsvoll, Henrik, Yuan, C., Lin, L., Ploug, Michael & Huang, M., 9 Mar 2012, In: Journal of Molecular Biology. 416, 5, p. 629-41 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  101. Published

    C4.4A er en ny biomarkør i ikke-småcellet lungekræft

    Kriegbaum, M. C., Jacobsen, B., Santoni-Rugiu, E. & Ploug, Michael, 2012, In: Best Practice Onkologie. 2, 5, p. 58-61

    Research output: Contribution to journalReviewResearch

  102. Published

    Quantitative PET of human urokinase-type plasminogen activator receptor with 64Cu-DOTA-AE105: implications for visualizing cancer invasion

    Persson, M., Madsen, J., Østergaard, S., Wessel, Mette Munk, Jørgensen, Jesper Tranekjær, Stræde, Karina, Lehmann, C., Ploug, Michael & Kjær, Andreas, 2012, In: Journal of Nuclear Medicine. 53, 1, p. 138-45 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  103. Published

    Urokinase-type plasminogen activator-like proteases in teleosts lack genuine receptor-binding epidermal growth factor-like domains

    Bager, R., Kristensen, T. K., Jensen, J., Szczur, A., Christensen, A., Andersen, L., Johansen, J. S., Larsen, N., Baatrup, E., Huang, M., Ploug, Michael & Andreasen, P. A., 2012, In: The Journal of Biological Chemistry. 287, 33, p. 27526-27536 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  104. 2011
  105. Published

    Rational targeting of the urokinase receptor (uPAR): development of antagonists and non-invasive imaging probes

    Kriegbaum, M. C., Persson, M., Haldager, L., Alpizar, W. E. A., Jacobsen, B., Gårdsvoll, H., Kjær, Andreas & Ploug, Michael, Nov 2011, In: Current Drug Targets. 12, 12, p. 1711-1728 18 p.

    Research output: Contribution to journalReviewResearchpeer-review

  106. Published

    Plasmodium ookinetes coopt mammalian plasminogen to invade the mosquito midgut

    Ghosh, A. K., Coppens, I., Gårdsvoll, Henrik, Ploug, Michael & Jacobs-Lorena, M., 11 Oct 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 41, p. 17153-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  107. Published

    Conformational regulation of urokinase receptor function: impact of receptor occupancy and epitope-mapped monoclonal antibodies on lamellipodia induction

    Gårdsvoll, Henrik, Jacobsen, B., Kriegbaum, M. C., Behrendt, Niels, Engelholm, Lars Henning, Østergaard, S. & Ploug, Michael, 23 Sep 2011, In: The Journal of Biological Chemistry. 286, 38, p. 33544-56 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  108. Published

    Expression of C4.4A, a structural uPAR homolog, reflects squamous epithelial differentiation in the adult mouse and during embryogenesis

    Kriegbaum, M. C., Jacobsen, B., Hald, A. & Ploug, Michael, 1 Feb 2011, In: Journal of Histochemistry and Cytochemistry. 59, 2, p. 188-201 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  109. Published

    C4.4A IS A PROGNOSTIC INDICATOR IN NON-SMALL CELL LUNG CANCER PATIENTS WITH ADENOCARCINOMAS

    Jacobsen, B., Muley, T., Meister, M., Dienemann, H., Christensen, I. J., Santoni Rugiu, Eric, Laerum, O. D. & Ploug, Michael, 2011, In: Journal of Thoracic Oncology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  110. Published

    C4.4A as a biomarker for poor prognosis in non-small cell lung cancer patients with adenocarcinomas

    Jacobsen, B., Muley, T., Meister, M., Dienemann, H., Christensen, I. J., Santoni Rugiu, Eric, Laerum, O. D. & Ploug, Michael, 2011, In: European Journal of Cancer.

    Research output: Contribution to journalJournal articleResearchpeer-review

  111. Published

    Mimicry of the regulatory role of urokinase in lamellipodia formation by introduction of a non-native interdomain disulfide bond in its receptor

    Gårdsvoll, Henrik, Kjærgaard, M., Jacobsen, B., Kriegbaum, M. C., Huang, M. & Ploug, Michael, 2011, In: Journal of Biological Chemistry. 286, 50, p. 43515-26 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  112. Published

    Proteasernes veje og vildveje

    Andreasen, P., Kjaer, A., Persson, M. & Ploug, Michael, 2011, In: Aktuel Naturvidenskab. 6, p. 24-27

    Research output: Contribution to journalReviewResearch

  113. 2010
  114. Published

    INDUCTION AND/OR MAINTENANCE OF TUMOR DORMANCY BY DISRUPTION OF UROKINASE PLASMINOGEN ACTIVATOR RECEPTOR-INTEGRIN INTERACTION

    Ossowski, L., Chaurasia, P., Aguirre-Ghiso Julio, A., Zhou, M. & Ploug, Michael, 30 Sep 2010, IPC No. G06G 7/ 60 A I, Patent No. US2010249184, Priority date 17 Mar 2008, Priority No. US20080531502

    Research output: Patent

  115. Published

    Selective abrogation of the uPA-uPAR interaction in vivo reveals a novel role in suppression of fibrin-associated inflammation

    Connolly, B. M., Choi, E. Y., Gårdsvoll, Henrik, Bey, A. L., Currie, B. M., Chavakis, T., Liu, S., Molinolo, A., Ploug, Michael, Leppla, S. H. & Bugge, T. V., 2 Sep 2010, In: Blood Weekly. 116, 9, p. 1593-603 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  116. Published

    Structure-based engineering of species selectivity in the interaction between urokinase and its receptor: implication for preclinical cancer therapy

    Lin, L., Gårdsvoll, Henrik, Huai, Q., Huang, M. & Ploug, Michael, 2 Apr 2010, In: Journal of Biological Chemistry. 285, 14, p. 10982-92 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  117. 2009
  118. Published

    Specific recognition of the C-terminal end of A beta 42 by a high affinity monoclonal antibody

    Axelsen, T. V., Holm, A., Birkelund, S., Christiansen, G., Ploug, Michael & Holm, I. E., Jul 2009, In: Molecular Immunology. 46, 11-12, p. 2267-73 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  119. Published

    Interactions of plasminogen activator inhibitor-1 with vitronectin involve an extensive binding surface and induce mutual conformational rearrangements

    Blouse, G. E., Dupont, D. M., Schar, C. R., Jensen, J. K., Minor, K. H., Anagli, J. Y., Gårdsvoll, Henrik, Ploug, Michael, Peterson, C. B. & Andreasen, P. A., 3 Mar 2009, In: Biochemistry. 48, 8, p. 1723-35 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  120. Published

    Expression of C4.4A in precursor lesions of non-small cell lung cancer

    Jacobsen, B., Santoni Rugiu, Eric, Illemann, M., Laerum, O. D. & Ploug, Michael, 2009, In: Journal of Thoracic Oncology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  121. PLAUR (Plasminogen activator, urokinase receptor

    Jacobsen, B., Illemann, M. & Ploug, Michael, 2009

    Research output: Other contributionNet publication - Internet publicationResearchpeer-review

  122. 2008
  123. Published

    Imaging of urokinase-type plasminogen activator receptor expression using a 64Cu-labeled linear peptide antagonist by microPET

    Li, Z., Niu, G., Wang, H., He, L., Yang, L., Ploug, Michael & Chen, X., 1 Aug 2008, In: Clinical Cancer Research. 14, 15, p. 4758-66 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  124. Published

    A composite role of vitronectin and urokinase in the modulation of cell morphology upon expression of the urokinase receptor

    Hillig, T., Engelholm, Lars Henning, Ingvarsen, S., Madsen, Daniel Hargbøl, Gårdsvoll, Henrik, Larsen, J. K., Ploug, Michael, Danø, K., Kjøller, L. & Behrendt, Niels, 30 May 2008, In: Journal of Biological Chemistry. 283, 22, p. 15217-15223 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  125. Published

    Altered expression of the urokinase receptor homologue, C4.4A, in invasive areas of human esophageal squamous cell carcinoma

    Hansen, L. V., Laerum, O. D., Illemann, M., Nielsen, B. S. & Ploug, Michael, 15 Feb 2008, In: International Journal of Cancer. Supplement. 122, 4, p. 734-41 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  126. Published

    Hydrogen atom scrambling in selectively labeled anionic peptides upon collisional activation by MALDI tandem time-of-flight mass spectrometry

    Bache, N., Rand, Kasper Dyrberg, Roepstorff, P., Ploug, Michael & Jørgensen, T., 2008, In: Journal of The American Society for Mass Spectrometry. 19, 12, p. 1719-25 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  127. LYPD3 (LY6/PLAUR domain containing 3

    Jacobsen, B. & Ploug, Michael, 2008

    Research output: Other contributionNet publication - Internet publicationResearchpeer-review

  128. Structure and inhibition of the urokinase-type plasminogen activator receptor(uPAR)

    Jacobsen, B., Kjaergaard, M., Gårdsvoll, H. & Ploug, Michael, 2008, The Cancer Degradome: Proteases and Cancer Biology. Edwards, D., Høyer-Hansen, G., Blasi, F. & Sloane, B. L. (eds.). Springer Verlag, p. 699-719

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  129. Published

    Structure and ligand interactions of the urokinase receptor (uPAR)

    Kjærgaard, M., Hansen, L. V., Jacobsen, B., Gårdsvoll, H. & Ploug, Michael, 2008, In: Frontiers in Bioscience. 13, p. 5441-5461 21 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  130. Published

    The urokinase receptor and its structural homologue C4.4A in human cancer: expression, prognosis and pharmacological inhibition

    Jacobsen, B. & Ploug, Michael, 2008, In: Current Medicinal Chemistry. 15, 25, p. 2559-73 15 p.

    Research output: Contribution to journalReviewResearchpeer-review

  131. 2007
  132. Published

    Tumour cell expression of C4.4A, a structural homologue of the urokinase receptor, correlates with poor prognosis in non-small cell lung cancer

    Hansen, L. V., Skov, B. G., Ploug, Michael & Pappot, Helle, Nov 2007, In: Lung Cancer. 58, 2, p. 260-6 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  133. Published

    Mapping of the vitronectin-binding site on the urokinase receptor: involvement of a coherent receptor interface consisting of residues from both domain I and the flanking interdomain linker region

    Gårdsvoll, Henrik & Ploug, Michael, 4 May 2007, In: The Journal of Biological Chemistry. 282, 18, p. 13561-72 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  134. Published

    A new tagging system for production of recombinant proteins in Drosophila S2 cells using the third domain of the urokinase receptor

    Gårdsvoll, Henrik, Hansen, L. V., Jørgensen, Thomas & Ploug, Michael, Apr 2007, In: Protein Expression and Purification. 52, 2, p. 384-94 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  135. One-step affinity purification of recombinant urokinase-type plasminogen activator receptor using a synthetic peptide developed by combinatorial chemistry

    Jacobsen, B., Gårdsvoll, Henrik, Juhl Funch, G., Ostergaard, S., Barkholt, V. & Ploug, Michael, Apr 2007, In: Protein Expression and Purification. 52, 2, p. 286-96 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  136. 2006
  137. Published

    Characterization of the functional epitope on the urokinase receptor. Complete alanine scanning mutagenesis supplemented by chemical cross-linking

    Gårdsvoll, Henrik, Gilquin, B., Le Du, M. H., Ménèz, A., Jørgensen, Thomas & Ploug, Michael, 14 Jul 2006, In: The Journal of Biological Chemistry. 281, 28, p. 19260-72 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  138. Published

    A region in urokinase plasminogen receptor domain III controlling a functional association with alpha5beta1 integrin and tumor growth

    Chaurasia, P., Aguirre-Ghiso, J., Liang, O. D., Gardsvoll, H., Ploug, Michael & Ossowski, L., 26 May 2006, In: The Journal of Biological Chemistry. 281, 21, p. 14852-63 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  139. Published

    Peptide antagonists of the human urokinase receptor and method for selecting them

    Ploug, Michael, Oestergaard, S., Holst-Hansen, C., Stephens, R., Danoe, K. & Holm, A., 11 Apr 2006, IPC No. A61K 38/ 00 A N, Patent No. US7026282, Priority date 1 Jul 1999, Priority No. WO1999DK00377

    Research output: Patent

  140. Plasminogen activation independent of uPA and tPA maintains wound healing in gene-deficient mice

    Lund, L. R., Green, K. A., Stoop, A. A., Ploug, Michael, Almholt, K., Lilla, J., Nielsen, B. S., Christensen, I. J., Craik, C. S., Werb, Z., Danø, K. & Rømer, J., 2006, In: EMBO Journal. 25, 12, p. 2686-97 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  141. 2005
  142. Published

    Collisional activation by MALDI tandem time-of-flight mass spectrometry induces intramolecular migration of amide hydrogens in protonated peptides

    Jørgensen, Thomas, Bache, N., Roepstorff, P., Gårdsvoll, Henrik & Ploug, Michael, Dec 2005, In: Molecular and Cellular Proteomics. 4, 12, p. 1910-9 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  143. Published

    Crystal structure of the human urokinase plasminogen activator receptor bound to an antagonist peptide

    Llinas, P., Le Du, M. H., Gårdsvoll, Henrik, Danø, K., Ploug, Michael, Gilquin, B., Stura, E. A. & Ménèz, A., 4 May 2005, In: E M B O Journal. 24, 9, p. 1655-63 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  144. Published

    Intramolecular migration of amide hydrogens in protonated peptides upon collisional activation

    Jørgensen, Thomas, Gårdsvoll, Henrik, Ploug, Michael & Roepstorff, P., 2 Mar 2005, In: Journal of the American Chemical Society. 127, 8, p. 2785-93 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  145. Published

    Plasminogen activation and cancer

    Danø, K., Behrendt, N., Hoyer-Hansen, G., Johnsen, M., Lund, L. R., Ploug, Michael & Nielsen, J. R., 2005, In: Thrombosis and Haemostasis. 93, 4, p. 676-681 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  146. 2004
  147. Published

    Dynamics of urokinase receptor interaction with Peptide antagonists studied by amide hydrogen exchange and mass spectrometry

    Jørgensen, Thomas, Gårdsvoll, Henrik, Danø, K., Roepstorff, P. & Ploug, Michael, 30 Nov 2004, In: Biochemistry. 43, 47, p. 15044-57 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  148. Published

    IMMUNOASSAYS FOR THE DETECTION OF UROKINASE RECEPTOR FORMS

    Piironen, T., Hoeyer-Hansen, G., Bruenner, N., Ploug, Michael, List, K., Laursen, B., Danoe, K., Liljas, H., Haese, A., Hartwig, H., Toernblom, M. & Gustafsson, O., 18 Nov 2004, IPC No. G06F 19/ 20 A N, Patent No. WO2004099780, Priority date 6 May 2003, Priority No. DK20030000676

    Research output: Patent

  149. Published

    Specific immunoassays for detection of intact and cleaved forms of the urokinase receptor

    Piironen, T., Laursen, B., Pass, J., List, K., Gårdsvoll, Henrik, Ploug, Michael, Danø, K. & Høyer-Hansen, G., Nov 2004, In: Clinical Chemistry. 50, 11, p. 2059-68 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  150. Published

    Structural analysis and tissue localization of human C4.4A: a protein homologue of the urokinase receptor

    Hansen, L. V., Gårdsvoll, Henrik, Nielsen, B. S., Lund, L. R., Danø, K., Jensen, O. N. & Ploug, Michael, 15 Jun 2004, In: Biochemical Journal. 380, Pt 3, p. 845-57 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  151. Published

    Characterization of low-glycosylated forms of soluble human urokinase receptor expressed in Drosophila Schneider 2 cells after deletion of glycosylation-sites

    Gårdsvoll, Henrik, Werner, F., Søndergaard, Leif, Danø, K. & Ploug, Michael, 2004, In: Protein Expression and Purification. 34, 2, p. 284-295 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  152. Published

    The urokinase receptor as a potential target in cancer therapy

    Romer, J., Nielsen, B. S. & Ploug, Michael, 2004, In: Current Pharmaceutical Design. 10, 19, p. 2359-76 18 p.

    Research output: Contribution to journalReviewResearchpeer-review

  153. 2003
  154. Published

    Urokinase-type plasminogen activator receptor

    Dano, K., Blasi, F., Roldan, Ann, L., Cubellis, Maria, V., Masucci, Maria, T., Appella, E., Schleuning, W-D., Behrendt, N., Ronne, E., Kristensen, P., Pollanen, J., Salonen, E-M., Stephens, Ross, W., Tapiovaara, H., Vaheri, A., Moller Lisbeth, B., Ellis, V., Lund Leif, R., Ploug, M., Pyke, C. & 1 others, Patthy, L., 6 Feb 2003, IPC No. A61K 38/ 00 A N, Patent No. US2003027981, Priority date 8 Jan 2001, Priority No. US20010755109

    Research output: Patent

  155. Published

    Structure-function relationships in the interaction between the urokinase-type plasminogen activator and its receptor

    Ploug, Michael, 2003, In: Current Pharmaceutical Design. 9, 19, p. 1499-528 30 p.

    Research output: Contribution to journalReviewResearchpeer-review

  156. 2002
  157. Structural analysis of the interaction between urokinase-type plasminogen activator and its receptor: a potential target for anti-invasive cancer therapy

    Ploug, Michael, Gårdsvoll, Henrik, Jørgensen, T. J. D., Lønborg Hansen, L. & Danø, K., Apr 2002, In: Biochemical Society Transactions. 30, 2, p. 177-183 7 p.

    Research output: Contribution to journalReviewResearchpeer-review

  158. 2001
  159. Peptide-derived antagonists of the urokinase receptor. Affinity maturation by combinatorial chemistry, identification of functional epitopes, and inhibitory effect on cancer cell intravasation

    Ploug, Michael, Østergaard, S., Gårdsvoll, Henrik, Kovalski, K., Holst-Hansen, C., Holm, A., Ossowski, L. & Danø, K., 9 Oct 2001, In: Biochemistry. 40, 40, p. 12157-68 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  160. The murine receptor for urokinase-type plasminogen activator is primarily expressed in tissues actively undergoing remodeling

    Solberg, H., Ploug, Michael, Høyer-Hansen, G., Nielsen, B. S. & Lund, L. R., Feb 2001, In: Journal of Histochemistry and Cytochemistry. 49, 2, p. 237-46 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  161. 2000
  162. Plasminogen-independent initiation of the pro-urokinase activation cascade in vivo. Activation of pro-urokinase by glandular kallikrein (mGK-6) in plasminogen-deficient mice

    List, K., Jensen, O. N., Bugge, T. H., Lund, L. R., Ploug, Michael, Danø, K. & Behrendt, Niels, 25 Jan 2000, In: Biochemistry. 39, 3, p. 508-15 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  163. 1999
  164. Mapping part of the functional epitope for ligand binding on the receptor for urokinase-type plasminogen activator by site-directed mutagenesis

    Gårdsvoll, Henrik, Danø, K. & Ploug, Michael, 31 Dec 1999, In: The Journal of Biological Chemistry. 274, 53, p. 37995-8003 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  165. Published

    Vectors and methods for recombinant production of uPA-binding fragments of the human urokinase-type plasminogen receptor (uPAR)

    Danoe, K., Blasi, F., Roldan, Ann, L., Cubellis, Maria, V., Masucci, Maria, T., Appella, E., Schleuning, W-D., Behrendt, N., Rønne, E., Kristensen, P., Pollanen, J., Salonen, E-M., Stephens, Ross, W., Tapiovaara, H., Vaheri, A., Moeller, Lisbeth, B., Ellis, V., Lund, Leif, R., Ploug, M., Pyke, C. & 1 others, Patthy, L., 6 Apr 1999, IPC No. A61K 38/ 00 A N, Patent No. US5891664, Priority date 6 Oct 1994, Priority No. US19940319052

    Research output: Patent

  166. 1998
  167. Glycosylation profile of a recombinant urokinase-type plasminogen activator receptor expressed in Chinese hamster ovary cells

    Ploug, Michael, Rahbek-Nielsen, H., Nielsen, P. F., Roepstorff, P. & Dano, K., 29 May 1998, In: The Journal of Biological Chemistry. 273, 22, p. 13933-43 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  168. Photoaffinity labeling of the human receptor for urokinase-type plasminogen activator using a decapeptide antagonist. Evidence for a composite ligand-binding site and a short interdomain separation

    Ploug, Michael, Østergaard, S., Hansen, L. B. L., Holm, A. & Danø, K., 17 Mar 1998, In: Biochemistry. 37, 11, p. 3612-22 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  169. 1997
  170. The intact urokinase receptor is required for efficient vitronectin binding: receptor cleavage prevents ligand interaction

    Høyer-Hansen, G., Behrendt, Niels, Ploug, Michael, Danø, K. & Preissner, K. T., 22 Dec 1997, In: FEBS Letters. 420, 1, p. 79-85 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  171. Published

    The rntact urokinase receptor is required for high affinity vitronectin binding: receptor cleavage prevents ligand interaction

    GunillaHaver-Hansjan, Behrendt, Niels, Ploug, Michael, Dana, K. & Preissner, K. T., 1 Dec 1997, In: Fibrinolysis and Proteolysis. 11, SUPPL. 3, 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  172. Cell-surface acceleration of urokinase-catalyzed receptor cleavage

    Høyer-Hansen, G., Ploug, Michael, Behrendt, Niels, Rønne, Elsebeth & Danø, K., 15 Jan 1997, In: European Journal of Biochemistry. 243, 1-2, p. 21-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  173. Structure, function and expression on blood and bone marrow cells of the urokinase-type plasminogen activator receptor, uPAR

    Plesner, T., Behrendt, Niels & Ploug, Michael, 1997, In: Stem Cells. 15, 6, p. 398-408 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  174. 1996
  175. uPA binding sites on domain 2+3 on uPAR and antibodies reactive therewith

    Pessara, U., Weidle, U., Koenig, B., Kohnert, U., Bartke, I., Dano, K., Ploug, Michael & Ellis, V., 10 Jan 1996, IPC No. C12R 1/ 91 A N, Patent No. EP0691350, Priority date 8 Jul 1994, Priority No. DK19940000831

    Research output: Patent

  176. Gene expression and function of the cellular receptor for uPA (uPAR)

    Ellis, V., Ploug, Michael, Plesner, T. & Danø, K., 1996, Fibrinolysis in Disease. Glas-Greenwalt, P. (ed.). CRC Press, p. 30-42

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  177. 1995
  178. Chemical modification of the urokinase-type plasminogen activator and its receptor using tetranitromethane. Evidence for the involvement of specific tyrosine residues in both molecules during receptor-ligand interaction

    Ploug, Michael, Rahbek-Nielsen, H., Ellis, V., Roepstorff, P. & Danø, K., 3 Oct 1995, In: Biochemistry. 34, 39, p. 12524-34 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  179. 1994
  180. Ligand interaction between urokinase-type plasminogen activator and its receptor probed with 8-anilino-1-naphthalenesulfonate. Evidence for a hydrophobic binding site exposed only on the intact receptor

    Ploug, Michael, Ellis, V. & Danø, K., 2 Aug 1994, In: Biochemistry. 33, 30, p. 8991-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  181. Structure-function relationships in the receptor for urokinase-type plasminogen activator. Comparison to other members of the Ly-6 family and snake venom alpha-neurotoxins

    Ploug, Michael & Ellis, V., 1 Aug 1994, In: FEBS Letters. 349, 2, p. 163-8 6 p.

    Research output: Contribution to journalReviewResearchpeer-review

  182. The receptor for urokinase-type plasminogen activator and urokinase is translocated from two distinct intracellular compartments to the plasma membrane on stimulation of human neutrophils

    Plesner, T., Ploug, Michael, Ellis, V., Rønne, E., Høyer-Hansen, G., Wittrup, M., Pedersen, T. L., Tscherning, T., Danø, K. & Hansen, N. E., 1 Feb 1994, In: Blood. 83, 3, p. 808-15 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  183. Published

    Quantitation of the receptor for urokinase plasminogen activator by enzyme-linked immunosorbent assay

    Rønne, Elsebeth, Behrendt, Niels, Ploug, Michael, Nielsen, H. J., Wöllisch, E., Weidle, U., Danø, K. & Høyer-Hansen, G., 3 Jan 1994, In: Journal of Immunological Methods. 167, 1-2, p. 91-101 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  184. The urokinase receptor. Protein structure and role in plasminogen activation and cancer invasion

    Danø, K., Behrendt, Niels, Brünner, N., Ellis, V., Ploug, Michael & Oyke, C., 1994, In: Fibrinolysis. 8, Supplement 1, p. 189-203

    Research output: Contribution to journalReviewResearchpeer-review

  185. 1993
  186. Localization of the disulfide bonds in the NH2-terminal domain of the cellular receptor for human urokinase-type plasminogen activator. A domain structure belonging to a novel superfamily of glycolipid-anchored membrane proteins

    Ploug, Michael, Kjalke, M., Rønne, E., Weidle, U., Høyer-Hansen, G. & Danø, K., 15 Aug 1993, In: The Journal of Biological Chemistry. 268, 23, p. 17539-46 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  187. Published

    Cellular receptor for urokinase-type plasminogen activator: protein structure

    Behrendt, Niels, Ploug, Michael, Rønne, Elsebeth, Høyer-Hansen, G. & Danø, K., 1993, Methods of Enzymology. Vol. 223. p. 207-22 16 p. (Methods in Enzymology).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  188. 1992
  189. Urokinase plasminogen activator cleaves its cell surface receptor releasing the ligand-binding domain

    Høyer-Hansen, G., Rønne, E., Solberg, H., Behrendt, Niels, Ploug, Michael, Lund, L. R., Ellis, V. & Danø, K., 5 Sep 1992, In: The Journal of Biological Chemistry. 267, 25, p. 18224-18229 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  190. A soluble form of the glycolipid-anchored receptor for urokinase-type plasminogen activator is secreted from peripheral blood leukocytes from patients with paroxysmal nocturnal hemoglobinuria

    Ploug, Michael, Eriksen, J., Plesner, T., Hansen, N. E. & Danø, K., 1 Sep 1992, In: European Journal of Biochemistry. 208, 2, p. 397-404 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  191. Structural requirements for glycosyl-phosphatidylinositol-anchor attachment in the cellular receptor for urokinase plasminogen activator

    Møller, L. B., Ploug, Michael & Blasi, F., 1 Sep 1992, In: European Journal of Biochemistry. 208, 2, p. 493-500 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  192. Identification and characterization of the murine cell surface receptor for the urokinase-type plasminogen activator

    Solberg, H., Løber, D., Eriksen, J., Ploug, Michael, Rønne, E., Behrendt, Niels, Danø, K. & Høyer-Hansen, G., 15 Apr 1992, In: European Journal of Biochemistry. 205, 2, p. 451-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  193. The receptor for urokinase-type plasminogen activator is deficient on peripheral blood leukocytes in patients with paroxysmal nocturnal hemoglobinuria

    Ploug, Michael, Plesner, T., Rønne, E., Ellis, V., Høyer-Hansen, G., Hansen, N. E. & Danø, K., 15 Mar 1992, In: Blood. 79, 6, p. 1447-55 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  194. In situ alkylation of cysteine residues in a hydrophobic membrane protein immobilized on polyvinylidene difluoride membranes by electroblotting prior to microsequence and amino acid analysis

    Ploug, Michael, Stoffer, B. B. & Jensen, A. L., Mar 1992, In: Electrophoresis. 13, 3, p. 148-53 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  195. 1991
  196. Published

    Cell-induced potentiation of the plasminogen activation system is abolished by a monoclonal antibody that recognizes the NH2-terminal domain of the urokinase receptor

    Rønne, Elsebeth, Behrendt, Niels, Ellis, V., Ploug, Michael, Danø, K. & Høyer-Hansen, G., 19 Aug 1991, In: FEBS Letters. 288, 1-2, p. 233-6 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  197. Protein structure and membrane anchorage of the cellular receptor for urokinase-type plasminogen activator

    Ploug, Michael, Behrendt, Niels, Løber, D. & Danø, K., Jul 1991, In: Seminars in Thrombosis and Hemostasis. 17, 3, p. 183-93 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  198. Cellular receptor for urokinase plasminogen activator. Carboxyl-terminal processing and membrane anchoring by glycosyl-phosphatidylinositol

    Ploug, Michael, Rønne, E., Behrendt, Niels, Jensen, A. L., Blasi, F. & Danø, K., 25 Jan 1991, In: The Journal of Biological Chemistry. 266, 3, p. 1926-33 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  199. 1990
  200. The human receptor for urokinase plasminogen activator. NH2-terminal amino acid sequence and glycosylation variants

    Behrendt, Niels, Rønne, Elsebeth, Ploug, Michael, Petri, T., Løber, D., Nielsen, L. S., Schleuning, W. D., Blasi, F., Appella, E. & Danø, K., 15 Apr 1990, In: The Journal of Biological Chemistry. 265, 11, p. 6453-60 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  201. The urokinase receptor and regulation of cell surface plasminogen activation

    Blasi, F., Cubellis, M. V., Masucci, M. T., Møller, L. B., Olson, D. P., Pedersen, N., Behrendt, Niels, Ellis, V., Ploug, Michael, Rønne, E. & Danø, K., 1990, In: Cell Differentation and Development. 32, 3, p. 247-54

    Research output: Contribution to journalJournal articleResearch

  202. 1989
  203. 1988
  204. Published

    Carbohydrate as covalent crosslink in human inter-alpha-trypsin inhibitor: a novel plasma protein structure

    Jessen, T. E., Faarvang, K. L. & Ploug, Michael, 28 Mar 1988, In: FEBS Letters. 230, 1-2, p. 195-200 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  205. 1987
  206. Published

    Localization and functional significance of a polymorphic determinant in the third component of human complement

    Behrendt, Niels, Hansen, Ole, Ploug, Michael, Barkholt, V. & Koch, C., Oct 1987, In: Molecular Immunology. 24, 10, p. 1097-103 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  207. 1985
  208. Published

    Hemolytic plate assay for quantification of active human complement component C3 using methylamine-treated plasma as complement source

    Ploug, Michael, Jessen, T. E., Welinder, K. G. & Barkholt, V., 1 May 1985, In: Analytical Biochemistry. 146, 2, p. 411-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 33978213